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Champions Oncology (CSBR)
NASDAQ:CSBR

Champions Oncology (CSBR) AI Stock Analysis

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CSBR

Champions Oncology

(NASDAQ:CSBR)

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Neutral 61 (OpenAI - 4o)
Rating:61Neutral
Price Target:
$7.50
▲(12.95% Upside)
The overall stock score of 61 reflects a balanced view of Champions Oncology's current position. The most significant factor is the company's financial performance, which shows profitability improvements but is weighed down by high leverage and cash flow challenges. Technical analysis supports a slightly bullish outlook, while the earnings call provides optimism with strong revenue growth and strategic investments. However, the high P/E ratio suggests overvaluation, limiting upside potential.
Positive Factors
Revenue Growth
The 11% YoY revenue growth indicates strong market demand and effective sales strategies, supporting long-term business expansion.
Improved Gross Margin
Higher gross margins reflect improved operational efficiencies, enhancing profitability and competitive positioning over time.
Strategic Investments
Investments in data platforms can drive innovation and strengthen partnerships, positioning the company for future growth.
Negative Factors
High Leverage
Significant leverage increases financial risk, potentially impacting the company's ability to invest in growth opportunities.
Cash Flow Challenges
Negative cash flow from operations can strain liquidity, limiting the company's ability to finance new projects without external funding.
Declining Revenue Growth
Negative revenue growth suggests challenges in maintaining market share, which could hinder long-term financial performance.

Champions Oncology (CSBR) vs. SPDR S&P 500 ETF (SPY)

Champions Oncology Business Overview & Revenue Model

Company DescriptionChampions Oncology (CSBR) is a biotechnology company that specializes in personalized medicine, particularly in the field of oncology. The company develops advanced technology platforms, including its proprietary TumorGraft® technology, which allows for the creation of patient-derived tumor models for use in drug development and treatment selection. By providing solutions that enhance the understanding of cancer biology and treatment responses, Champions Oncology serves pharmaceutical companies, academic institutions, and healthcare providers globally.
How the Company Makes MoneyChampions Oncology generates revenue primarily through its services related to tumor models and personalized medicine solutions. The company earns money from its TumorGraft platform by offering preclinical services to pharmaceutical companies, which include drug efficacy testing and biomarker studies. Additionally, the company has established partnerships with various pharmaceutical firms that may involve collaborative research agreements and licensing deals, contributing to its revenue streams. The company also provides consulting services and engages in strategic collaborations that can enhance its earnings potential. Overall, its revenue model is centered on providing high-value, data-driven insights that help accelerate the drug development process for oncology therapies.

Champions Oncology Key Performance Indicators (KPIs)

Any
Any
Revenue By Segment
Revenue By Segment
Breaks down revenue by different business segments, highlighting which areas are driving growth and profitability. This can indicate strategic focus and potential areas for expansion or risk.
Chart InsightsChampions Oncology's Pharmacology Services segment shows a recent uptick, but Personalized Oncology Services have stagnated, indicating a strategic shift. The TOS License segment's emergence is notable, contributing significantly to recent revenue. The latest earnings call highlights a revenue rebound driven by the TOS business and data platform, despite challenges like flat year-over-year revenue and declining gross margins. The company is optimistic about future growth, focusing on its data and Corellia businesses, which could drive sequential revenue growth and margin expansion in fiscal 2026.
Data provided by:The Fly

Champions Oncology Earnings Call Summary

Earnings Call Date:Dec 15, 2025
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Mar 17, 2026
Earnings Call Sentiment Positive
The earnings call showcased strong year-over-year revenue growth and improved gross margins, indicating a positive trajectory for Champions Oncology. Strategic investments in radiolabeling and the data platform are expected to drive long-term growth. However, increased operating expenses and cash flow challenges present areas of concern. Overall, the company's positive financial performance and strategic direction suggest a favorable outlook.
Q2-2026 Updates
Positive Updates
Year-over-Year Revenue Growth
Revenue for the second quarter was $15 million, an increase of 11% from $13.5 million last year, driven by improved conversion of booked work.
Improved Gross Margin
Gross margin improved to 52% from 45% last year, supported by operational efficiencies and a stable cost of sales.
Radiolabeling and Radiopharmaceutical Success
Continued success in radiolabeling and radiopharmaceutical support workflows, positioning Champions uniquely in the oncology drug development market.
Investment in Data Platform
Ongoing investment in enhancing the data platform's functionality to support pharmaceutical partners, with significant customer interest.
Positive Adjusted EBITDA
The company remains on track to achieve full-year positive adjusted EBITDA, one of its core financial goals for fiscal 2026.
Negative Updates
Increased Operating Expenses
Operating expenses for the quarter increased by $2 million from last year, mainly due to investments in the data platform and other strategic priorities.
Cash Flow Challenges
Net cash used in operating activities for the quarter was $1.9 million, primarily driven by a decrease in deferred revenue.
Company Guidance
During the Champions Oncology second quarter fiscal 2026 earnings call, CEO Robert Brainin outlined key guidance metrics for the company. Champions Oncology aims to achieve year-on-year revenue growth and maintain positive adjusted EBITDA for the full year. The company posted a total revenue of $15 million for the quarter, up 11% from the previous year, with a gross margin improvement to 52% from 45%. Operating expenses rose to $7 million, reflecting strategic investments in the data platform and commercial team. Net cash used in operating activities was $1.9 million, with $8.5 million in cash and no debt. The company is focused on leveraging its unique radiolabeling capabilities and expanding its data platform to drive long-term growth, while maintaining fiscal discipline without shareholder dilution. The management remains optimistic about its performance in the upcoming quarters, given the improving market conditions and increasing customer engagement.

Champions Oncology Financial Statement Overview

Summary
Champions Oncology has shown improvements in profitability and return on equity, but faces challenges with declining revenue growth and high leverage. The company's ability to generate cash flow is under pressure, as evidenced by the significant decline in free cash flow growth. While there are positive signs of recovery, particularly in profitability, the high debt levels and cash flow issues could pose risks if not addressed.
Income Statement
Champions Oncology has shown a mixed performance in its income statement. The company has managed to improve its gross profit margin to 50.15% in 2025, indicating efficient cost management. However, the revenue growth rate has been negative at -2.81%, reflecting a decline in sales. The net profit margin improved to 8.26% in 2025, a significant turnaround from previous losses, suggesting enhanced profitability. Despite these improvements, the EBIT and EBITDA margins remain relatively low, indicating potential challenges in operational efficiency.
Balance Sheet
The balance sheet reveals a high debt-to-equity ratio of 1.62 in 2025, indicating significant leverage and potential financial risk. However, the return on equity is strong at 124.63%, driven by improved net income. The equity ratio stands at 11.66%, suggesting a moderate level of equity financing. Overall, while the company has improved its profitability, the high leverage poses a risk to financial stability.
Cash Flow
The cash flow statement shows a concerning trend with a significant decline in free cash flow growth at -628.87% in 2025. The operating cash flow to net income ratio is 0.31, indicating that operating cash flow covers net income, but not robustly. The free cash flow to net income ratio is healthy at 94.73%, suggesting that the company is generating sufficient free cash flow relative to its net income. Despite this, the negative growth in free cash flow is a potential red flag.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue56.94M50.16M53.87M49.11M41.04M
Gross Profit26.91M20.75M24.34M25.48M19.59M
EBITDA6.29M-5.41M-2.07M3.00M2.02M
Net Income4.70M-7.28M-5.33M548.00K362.00K
Balance Sheet
Total Assets32.34M26.13M34.31M35.38M27.59M
Cash, Cash Equivalents and Short-Term Investments9.79M2.62M10.12M9.01M4.69M
Total Debt6.11M7.43M8.60M9.47M9.60M
Total Liabilities28.57M28.04M29.68M26.28M20.16M
Stockholders Equity3.77M-1.90M4.64M9.10M7.43M
Cash Flow
Free Cash Flow7.00M-6.97M1.08M4.11M-4.96M
Operating Cash Flow7.39M-6.14M3.96M6.50M-1.68M
Investing Cash Flow-389.00K-836.00K-2.87M-2.38M-3.17M
Financing Cash Flow170.00K-527.00K11.00K207.00K1.20M

Champions Oncology Technical Analysis

Technical Analysis Sentiment
Positive
Last Price6.64
Price Trends
50DMA
6.70
Positive
100DMA
6.72
Positive
200DMA
6.97
Negative
Market Momentum
MACD
0.03
Positive
RSI
50.88
Neutral
STOCH
28.89
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CSBR, the sentiment is Positive. The current price of 6.64 is below the 20-day moving average (MA) of 6.84, below the 50-day MA of 6.70, and below the 200-day MA of 6.97, indicating a neutral trend. The MACD of 0.03 indicates Positive momentum. The RSI at 50.88 is Neutral, neither overbought nor oversold. The STOCH value of 28.89 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CSBR.

Champions Oncology Risk Analysis

Champions Oncology disclosed 30 risk factors in its most recent earnings report. Champions Oncology reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Champions Oncology Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$94.30M40.81102.74%9.06%
59
Neutral
$160.84M28.7812.64%35.42%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$112.58M-9.92-57.94%11.78%
45
Neutral
$84.35M-2.78-48.89%-9.42%
42
Neutral
$103.38M-0.97-85.44%-505.96%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CSBR
Champions Oncology
6.79
-2.38
-25.94%
SAVA
Cassava Sciences
2.14
-0.59
-21.61%
PLX
Protalix
2.00
-0.20
-9.09%
ATOS
Atossa Therapeutics
0.65
-0.27
-29.02%
ANIX
Anixa Biosciences
3.42
1.23
56.16%
ACTU
Actuate Therapeutics, Inc.
6.28
-1.80
-22.28%

Champions Oncology Corporate Events

Executive/Board ChangesShareholder Meetings
Champions Oncology Holds Annual Stockholders Meeting
Positive
Oct 16, 2025

On October 16, 2025, Champions Oncology, Inc. held its Annual Meeting of Stockholders, where key decisions were made. The company’s seven director nominees were elected for a one-year term, and the appointment of EisnerAmper LLP as the independent registered public accounting firm was ratified. Additionally, a non-binding advisory resolution on executive compensation was approved, indicating shareholder support for the company’s leadership and strategic direction.

The most recent analyst rating on (CSBR) stock is a Hold with a $6.50 price target. To see the full list of analyst forecasts on Champions Oncology stock, see the CSBR Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 19, 2025