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Crispr Therapeutics AG (CRSP)
NASDAQ:CRSP
Ctx112
Lupus Erythematosus, Systemic, Lupus Nephritis, Systemic Sclerosis, Myositis, Sle (Systemic Lupus), Inflammatory Myopathy, Idiopathic, Diffuse Cutaneous Systemic Sclerosis
Phase I
Recruiting
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
Mar 25, 2025
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Ctx131
Acute Myeloid Leukemia, T Cell Lymphoma, B Cell Lymphoma
Phase I/II
Recruiting
A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed/Refractory Hematologic Malignancies
Jun 21, 2024
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Ctx001
Hemoglobinopathies, Sickle Cell Disease, Hydroxyurea Failure, Hydroxyurea Intolerance, Hematological Diseases
Phase III
Recruiting
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)
Apr 07, 2022
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Ctx001
Hemoglobinopathies, Beta-Thalassemia, Genetic Diseases, Inborn, Hematologic Diseases, Thalassemia
Phase III
Recruiting
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)
Apr 07, 2022
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Ctx001
Hemoglobinopathies, Beta-Thalassemia, Sickle Cell Disease, Genetic Diseases, Inborn, Hematologic Diseases, Thalassemia, Sickle Cell Anemia
Phase III
Enrolling By Invitation
A Long-term Follow-up Study in Participants Who Received CTX001
Dec 20, 2019
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Ctx001
Hemoglobinopathies, Sickle Cell Disease, Hematological Diseases
Phase II/III
Completed
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease
Nov 09, 2018
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Ctx001
Hemoglobinopathies, Beta-Thalassemia, Genetic Diseases, Inborn, Hematologic Diseases, Thalassemia
Phase II/III
Active Not Recruiting
A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia
Aug 29, 2018
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Crispr Therapeutics AG (CRSP) have in its pipeline
CRSP is currently developing the following drugs: Ctx112, Ctx131, Ctx001. These drug candidates are in various stages of clinical development as the company works toward FDA approval.