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Cardiff Oncology, Inc. (CRDF)
:CRDF
Bevacizumab, Folfiri, Onvansertib, Folfox
Metastatic Colorectal Cancer, Crc, Kras/Nras Mutation
Phase II
Active Not Recruiting
Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation
Oct 24, 2023
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Bevacizumab, Folfiri, Onvansertib
Colorectal Cancer, Metastatic Colorectal Cancer
Phase II
Completed
Study of Onvansertib in Combination With FOLFIRI and Bevacizumab Versus FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer in Participants With a Kirsten Rat Sarcoma Virus Gene (KRAS) or Neuroblastoma-RAS (NRAS) Mutation
Oct 20, 2022
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Fluorouracil, Leucovorin, Nanoliposomal Irinotecan, Onvansertib
Pancreatic Ductal Adenocarcinoma
Phase II
Completed
Onvansertib in Combination with Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants with Metastatic Pancreatic Ductal Adenocarcinoma
Feb 09, 2021
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Bevacizumab, Folfiri, Onvansertib
Metastatic Colorectal Cancer, Kras Gene Mutation
Phase I/II
Completed
Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a KRAS Mutation
Feb 01, 2019
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Cardiff Oncology, Inc. (CRDF) have in its pipeline
CRDF is currently developing the following drugs: Bevacizumab, Folfiri, Onvansertib, Folfox, Bevacizumab, Folfiri, Onvansertib, Fluorouracil, Leucovorin, Nanoliposomal Irinotecan, Onvansertib. These drug candidates are in various stages of clinical development as the company works toward FDA approval.