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Caribou Biosciences (CRBU)
NASDAQ:CRBU
Cb-010
Lupus Nephritis, Systemic Lupus Erythematosus, Lupus Erythematosus, Lupus
Phase I
Withdrawn
CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)
Dec 18, 2024
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Cb-012
Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, In Relapse
Phase I
Terminated
CRISPR-Edited Allogeneic Anti-CLL-1 CAR-T Cell Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Nov 06, 2023
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Cb-011
Relapsed/Refractory Multiple Myeloma
Phase I
Recruiting
CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
Dec 19, 2022
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Cyclophosphamide, Fludarabine, Cb-010
Lymphoma, Non Hodgkin Lymphoma, Lymphoma, Non-Hodgkin, B Cell Lymphoma, Relapsed Non Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, B Cell Non-Hodgkin's Lymphoma
Phase I
Recruiting
CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
Nov 16, 2020
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Caribou Biosciences (CRBU) have in its pipeline
CRBU is currently developing the following drugs: Cb-010, Cb-012, Cb-011. These drug candidates are in various stages of clinical development as the company works toward FDA approval.