Cullinan Management (CGEM) AI Stock Analysis

• Market Cap: $444.38M
• Dividend Yield: N/A
• Average Volume (3M): 324.21K
• Price to Earnings (P/E): ―
• Beta (1Y): 1.24
• Revenue Growth: N/A
• EPS Growth: 15.34%
• Country: US
• Employees: 111
• Sector: Healthcare
• Sector Strength: 40
• Industry: Biotechnology
• EPS (TTM): -0.74
• Shares Outstanding: 59,014,668
• 10 Day Avg. Volume: 271,114
• 30 Day Avg. Volume: 324,210
• PEG Ratio: -0.64
• Price to Book (P/B): 0.80
• Price to Sales (P/S): 0.00
• P/FCF Ratio: -2.93
• Enterprise Value/Market Cap: 0.82
• Enterprise Value/Revenue: N/A
• Enterprise Value/Gross Profit: -4.74K
• Enterprise Value/Ebitda: -0.47
• 1Y Price Target: $27.43
• Price Target Upside: 264.76% Upside
• Rating Consensus: Strong Buy
• Number of Analyst Covering: 10

• Rating: 35 Underperform
• Price Target: ―

Cullinan Management's stock is facing significant challenges primarily due to its weak financial performance, characterized by persistent losses and negative cash flow. The technical analysis provides some short-term optimism, but the overall technical outlook remains bearish. The valuation is unattractive due to a negative P/E ratio and no dividend yield, indicating high risk for investors. The stock's potential is heavily reliant on strategic changes and improved financial health.

Positive Factors

Clinical Trial Results

Cullinan's Phase 2b data with zipalertinib shows best-in-class efficacy for a difficult-to-treat patient population with EGFR ex20ins mutations, offering a promising outlook for the treatment.

Licensing Agreement

The licensing of BCMA-targeted T-cell engager velinotamig is seen as highly complementary to existing projects and leverages CGEM’s expertise, promising significant potential in autoimmune diseases.

Product Administration Benefits

Zipalertinib offers the benefit of oral administration with less significant toxicities, making it a more convenient and safer option compared to other treatments like Rybrevant.

Negative Factors

CNS Activity Questions

Questions remain about zipalertinib's CNS activity, with limited data available on its effectiveness for patients with brain metastases.

Data Limitations

There is limited data available on zipalertinib's effectiveness in the context of patients treated with Rybrevant and chemo, creating uncertainty about its efficacy.

Market Competition

Potential FDA approval of sunvozertinib could introduce a competing treatment in the market, increasing risk for CGEM.

Cullinan Management Business Overview & Revenue Model

Company Description

Cullinan Oncology Inc., a biopharmaceutical company, focuses on developing a pipeline of targeted oncology and immuno-oncology therapies for cancer patients in the United States. The company's lead candidate is the CLN-081, an orally available small molecule that is in a Phase I/IIa dose escalation and expansion trial for treating patients with non-small cell lung cancer. Its preclinical products include CLN-049, a humanized bispecific antibody for the treatment of acute myeloid leukemia; CLN-619, a monoclonal antibody for the treatment of solid tumors; CLN-617, a fusion protein for the treatment of solid tumors; CLN-978, a T cell engaging antibody for B-cell malignancies; Opal, a bispecific fusion protein to block the PD-1 axis, and to activate the 4-IBB/CD137 pathway on T cells in tumors; and Jade, a cell therapy to target a novel senescence and cancer-related protein. The company has collaboration agreements with Cullinan Pearl Corp. to develop, manufacture, and commercialize CLN-081 and products containing CLN-081; and Adimab, LLC to discover and/or optimize antibodies. Cullinan Oncology, Inc. was incorporated in 2016 and is headquartered in Cambridge, Massachusetts.

How the Company Makes Money

Cullinan Oncology generates revenue primarily through strategic partnerships, collaborations, and licensing agreements with other pharmaceutical companies. These partnerships often involve milestone payments, royalties, and research funding, providing financial resources to advance their drug development programs. Additionally, Cullinan may earn revenue from out-licensing its pipeline candidates to commercial partners who have the capability to bring these therapies to market. The company's focus on developing promising oncology treatments positions it for potential future revenue from successful drug approvals and commercialization.

Cullinan Management Financial Statement Overview

Summary

Cullinan Management faces considerable financial challenges, with negative profitability and cash flow metrics. While the balance sheet maintains equity strength, the lack of revenue and ongoing losses indicate operational and sustainability risks. The company's heavy reliance on external financing underscores the need for strategic improvements to achieve financial stability.

Income Statement

Cullinan Management's income statement reveals significant challenges, with consistent negative net income and EBIT over the years and no revenue for the recent periods. The TTM (Trailing-Twelve-Months) data shows a substantial net loss, indicating persistent operational difficulties. The lack of revenue growth and negative profit margins highlight severe profitability issues.

Balance Sheet

The balance sheet shows a strong equity position, with stockholders' equity consistently higher than total debt, leading to a favorable debt-to-equity ratio. However, the company faces potential risks with its high liabilities relative to its total assets. The equity ratio remains stable, but the absence of revenue poses a long-term sustainability risk.

Cash Flow

The cash flow statement highlights negative free cash flow and operating cash flow trends, indicating cash burn concerns. The financing activities have been a primary source of cash, suggesting reliance on external funding. The inability to generate positive cash flow from operations poses a significant risk to financial health.

Breakdown	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	0.00	0.00	0.00	18.94M	0.00
Gross Profit	-306.00K	-310.00K	-93.00K	18.89M	-62.00K
EBITDA	-167.15M	-190.34M	151.41M	-67.90M	-60.27M
Net Income	-167.38M	-153.16M	111.21M	-65.57M	-51.80M
Balance Sheet
Total Assets	621.82M	484.18M	561.12M	437.19M	214.71M
Cash, Cash Equivalents and Short-Term Investments	398.98M	467.07M	467.29M	430.86M	210.21M
Total Debt	2.15M	3.59M	5.19M	0.00	0.00
Total Liabilities	31.50M	30.29M	26.09M	11.81M	291.05M
Stockholders Equity	590.33M	453.70M	535.03M	422.58M	-77.64M
Cash Flow
Free Cash Flow	-145.30M	-134.48M	-127.80M	-44.02M	-29.78M
Operating Cash Flow	-145.30M	-134.28M	-126.66M	-43.43M	-29.77M
Investing Cash Flow	-136.31M	35.81M	248.97M	-333.77M	-5.42M
Financing Cash Flow	266.19M	40.75M	-25.93M	268.78M	140.14M

Cullinan Management Technical Analysis

• Technical Analysis Sentiment: Negative
• Last Price: 7.52
• 50DMA: Negative
• 100DMA: Negative
• 200DMA: Negative
• MACD: Negative
• RSI: Neutral
• STOCH: Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CGEM, the sentiment is Negative. The current price of 7.52 is below the 20-day moving average (MA) of 7.68, below the 50-day MA of 8.00, and below the 200-day MA of 10.50, indicating a bearish trend. The MACD of -0.15 indicates Negative momentum. The RSI at 43.79 is Neutral, neither overbought nor oversold. The STOCH value of 33.35 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CGEM.

Cullinan Management Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
BCYC	60 Neutral	$592.37M	―	-37.13%	―	-38.14%	29.69%
IMTX	58 Neutral	$729.30M	53.85	-4.52%	―	92.31%	78.17%
URGN	56 Neutral	$705.49M	―	-452.20%	―	8.98%	6.32%
ARVN	53 Neutral	$536.49M	―	-35.41%	―	―	―
Sector *	52 Neutral	$7.37B	-0.04	-63.81%	2.59%	16.40%	<0.01%
KURA	47 Neutral	$550.62M	―	-41.84%	―	―	3.95%
CGEM	35 Underperform	$444.38M	―	-36.57%	―	―	15.34%

Cullinan Management Corporate Events

Cullinan Management Achieves Milestone in Cancer Trial

On January 28, 2025, Cullinan Therapeutics, in collaboration with Taiho Pharmaceutical and Taiho Oncology, announced that their REZILIENT1 trial successfully met its primary endpoint of overall response rate. The trial involved zipalertinib monotherapy for patients with non-small cell lung cancer harboring EGFR exon 20 insertion mutations. The results, consistent with previous data presentations, are from the Phase 2b part of the study, with plans to present full results at an upcoming international medical conference. The companies intend to seek U.S. regulatory approval in the latter half of 2025.