Clinical Trial ResultsData demonstrated promising, durable CLN-049 monotherapy activity in a heavily pretreated AML patient population.
Market ReactionCullinan shares closed up 17.5% following the positive results, with shares now up over 100% since early October.
Safety ProfileCLN-049 continues to show a safe and tolerable profile, with nearly all CRS limited to Grade 1/2 and the majority of CRS events occurring after a step-up dose or target dose 1.