Strong Product Revenue Growth and Raised Guidance
Q1 product revenue was $53.7M, up 24% year-over-year. Management raised full-year 2026 product revenue guidance to $227M–$231M (implying ~10%–12% YoY product revenue growth) and raised IFC guidance to $22M–$24M (~30%–40% growth for IFC).
Robust IFC / ISC Trajectory
First-quarter IFC/ISC momentum: IFC revenue was $5.7M vs $3.0M in Q1 2025 (~90% YoY revenue growth); therapeutic dose equivalents (ISC measure) increased ~120% YoY. Management cites early traction from BCA members and conversion from finished therapeutics to kit-based sales.
Platelet Franchise Strength and Market Penetration
North American platelet kit volumes (treatable doses) increased 69% YoY and North America comprised nearly 70% of Q1 product revenue. Early benefits from the Blood Centers of America (BCA) group purchasing agreement are noted, and international platelet demand (EMEA) also contributed to growth.
Broad Geographic Growth and FX Tailwind
Total revenue (including government contract revenue) rose 23% YoY. EMEA revenue grew 28% YoY, with EMEA FX contributing ~11% of that growth and consolidated FX contributing ~3% versus Q1 2025.
Improving Profitability Trends
GAAP net loss narrowed to $1.6M in Q1. Non-GAAP adjusted EBITDA was positive $4.0M, marking the eighth consecutive quarter of positive adjusted EBITDA, and company expects its third consecutive year of positive adjusted EBITDA in 2026 with line of sight to GAAP profitability.
Operating Discipline and R&D Efficiency
Operating expenses declined 7% YoY. SG&A was largely flat YoY. R&D spending declined as INT 200/INT 100 development winds toward regulatory submission and Cerus-funded R&D is trending down as a percent of total R&D (more spend shifted to government-reimbursed programs).
Cash Position and Long-Term Growth Track Record
Cash and equivalents of $80.4M (vs. $82.9M at 2025 year-end). Since 2019, product revenue CAGR is 18% and operating expenses have increased <3% annually, demonstrating operating leverage and sustained growth.
Regulatory & Product Milestones in Flight
Key near-term catalysts: PMA submission for illuminator device (INT 200/INT 100) planned this quarter with an anticipated U.S. launch in 2027; INTERCEPT red blood cell program completed RETA enrollment with expected readout Q4 2026 and ongoing ANSM review for CE Mark (management estimates potential H1 2027 timing).