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Codexis (CDXS)
NASDAQ:CDXS
US Market

Codexis (CDXS) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
Apr 30, 2026
After Close (Confirmed)
Period Ending
2026 (Q1)
Consensus EPS Forecast
-0.17
Last Year’s EPS
-0.25
Same Quarter Last Year
Moderate Buy
Based on 3 Analysts Ratings

Earnings Call Summary

Q4 2025
Earnings Call Date:Mar 11, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
The call highlighted substantial technical progress and commercial momentum for the ECOsynthesis platform (notable scale-up milestones, ISO 9001 certification, CDMO agreements, and a 55-opportunity pipeline) and showed improved financial metrics (higher revenue, stronger product gross margins, reduced annual net loss, and a strengthened cash position aided by a ~ $37.8M Merck agreement). At the same time, important risks remain: ECOsynthesis revenue is currently service-heavy with limited margin contribution, full-year net loss persists, R&D investments and GMP capex will continue to pressure cash, and many commercial relationships remain in feasibility or assessment stages. Given the number and significance of technical and commercial achievements that materially de-risk the business combined with remaining near-term financial and execution uncertainties, the overall tone is cautiously optimistic.
Company Guidance
Codexis guided 2026 revenue of $72–$76 million, with results expected to be skewed to the second half of the year (Q1 roughly in line with consensus), and said product gross margins should remain stable at ~64% (2025 product gross margin 64% vs 56% in the prior year); management expects combined operating expenses and capital expenditures in 2026 to be similar to 2025 after cost-savings from a Q4 restructuring ($3.4M charge). Key balance-sheet and cash metrics: $78.2 million in cash, cash equivalents and short-term investments at year-end 2025 (including the ~$37.8M Merck technology transfer), which they expect will fund operations and capex through 2027, and a 2025 revenue base of $70.4M (vs $59.3M in 2024). Operational and commercial targets for 2026 include scaling ECOsynthesis from current 100 g operations toward 0.5 kg by year-end, beginning GMP plant retrofit construction in H2 2026 to be fully operational by end-2027, pursuing additional licensing deals (one anticipated in 2026), and advancing a commercial pipeline of 55 opportunities across 40 companies (including a prototype 50 g, low‑seven‑figure contract).
Strong Revenue Growth and Improved Product Margins
Quarter revenue increased to $38.9M from $21.5M (≈+81% YoY), and full-year revenue rose to $70.4M from $59.3M (≈+19% YoY). Product gross margin improved to 64% in 2025 from 56% in 2024 (+8 percentage points). Management expects gross margins to remain stable in 2026.
Material Non-Dilutive Financing from Merck
Signed a technology transfer agreement with Merck that contributed approximately $37.8M (also referenced as ~$38M) in non-dilutive capital in Q4 2025, materially strengthening the cash position.
Healthy Cash Position and Runway
Ended 2025 with $78.2M in cash, cash equivalents, and short-term investments, which management expects will fund planned operations and capex through 2027.
Concrete ECOsynthesis Technical Milestones and Scale-Up
Delivered 10 grams of commercially relevant siRNA using full sequential ECOsynthesis and are currently operating at 100-gram scale in the Eco Innovation Lab with a target of achieving ~0.5 kg (500 g) scale by year-end 2026. Additionally, a client used Codexis ligase to manufacture a 3 kg batch of siRNA via chemoenzymatic production.
Commercial Engagements and Partner Wins
Signed three CDMO agreements in 2025 (Bachem, Nitto Avecia, Axolabs) and announced an emerging biotech contract to supply 50 grams of fully enzymatic siRNA (a low seven-figure agreement split between services and product). Sales pipeline contains 55 opportunities across 40 companies, indicating strong market interest.
Quality and Infrastructure Progress
Modernized non-GMP production capability in Redwood City and achieved ISO 9001 certification; passed a facility and quality management inspection by a large pharmaceutical customer. Leased a GMP plant in 2025 with retrofit construction planned to begin H2 2026 and expected to be operational by end of 2027.
Improved Operating Profitability Metrics
Net loss for the full year narrowed to $44.0M from $65.3M in the prior year (improvement of $21.3M, ≈32.6% reduction in annual net loss). Quarterly results showed a positive net income of $9.6M compared with a prior-year quarter loss of $10.4M.

Codexis (CDXS) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

CDXS Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
Apr 30, 2026
2026 (Q1)
-0.17 / -
-0.25
Mar 11, 2026
2025 (Q4)
-0.03 / 0.11
-0.13184.62% (+0.24)
Nov 06, 2025
2025 (Q3)
-0.15 / -0.22
-0.2924.14% (+0.07)
Aug 13, 2025
2025 (Q2)
-0.19 / -0.16
-0.3250.00% (+0.16)
May 14, 2025
2025 (Q1)
-0.24 / -0.25
-0.16-56.25% (-0.09)
Feb 27, 2025
2024 (Q4)
-0.04 / -0.13
-0.1-30.00% (-0.03)
Oct 31, 2024
2024 (Q3)
-0.24 / -0.29
-0.542.00% (+0.21)
Aug 08, 2024
2024 (Q2)
-0.26 / -0.32
-0.17-88.24% (-0.15)
May 02, 2024
2024 (Q1)
-0.18 / -0.16
-0.3452.94% (+0.18)
Feb 28, 2024
2023 (Q4)
-0.12 / -0.10
-0.1947.37% (+0.09)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

CDXS Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Mar 11, 2026
$1.27$1.71+34.65%
Nov 06, 2025
$2.04$1.69-16.95%
Aug 13, 2025
$3.05$3.10+1.64%
May 14, 2025
$2.47$2.51+1.62%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Codexis (CDXS) report earnings?
Codexis (CDXS) is schdueled to report earning on Apr 30, 2026, After Close (Confirmed).
    What is Codexis (CDXS) earnings time?
    Codexis (CDXS) earnings time is at Apr 30, 2026, After Close (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is CDXS EPS forecast?
          CDXS EPS forecast for the fiscal quarter 2026 (Q1) is -0.17.