Q4 Revenue Beat and Reported Revenue
Q4 2025 reported revenue of $977.2M was roughly flat year-over-year and came in about $20M above company expectations; full-year 2025 reported revenue was $3.44B, up 2.1% versus 2024.
Strong Cash Generation and Deleveraging
Q4 2025 operating cash flow was approximately $230M (company's highest), with free cash flow of $207.3M (up ~$54M YoY). Used cash for capex, Project Accelerate investments, and ~$145M debt repayment; year-end cash and short-term investments ~ $300M and leverage ~3.1x.
Order Momentum and Backlog
BSI book-to-bill was >1.0 for two consecutive quarters and company entered 2026 with a backlog of ~7 months of revenue, supporting management’s view that demand has passed the 2025 trough.
Acquisitions Contributing and Product Momentum
The three strategic 2024 acquisitions had first full year in 2025: ELITech and Chemspeed delivered mid- to high-single-digit organic revenue growth; NanoString approx. flat but spatial biology orders (including NanoString) grew double-digits organically in 2025. Several competitive product launches (AGBT, AACR, ASMS) showed strong initial demand expected to drive 2026+ growth.
Large Multiyear Orders for BEST and Research
BEST booked major multiyear superconducting wire agreements totaling over $500M across multiple years (late Q4 2025 and early 2026); research instruments received >$40M orders for enabling tech tied to the Extreme Light Infrastructure, expected to convert mostly in late 2026.
2026 Financial Guidance and Margin Targets
Management initiated FY2026 guidance: reported revenue growth 4–5% to $3.57–3.60B, organic growth 1–2%, estimated currency tailwind ~1.5%, and non-GAAP EPS guidance $2.10–$2.15 (reported EPS growth 15–17%). Targeting non-GAAP operating margin expansion of 250–300 bps in 2026 (implying 300–350 bps organic expansion before a ~50 bps currency headwind).
Expanded Cost Savings Plan
Project Accelerate cost-saving initiatives now expected to exceed prior $100–$120M target and management indicated annualized savings closer to $140M+ (with much of additional savings expected to be fully effective by mid-2026).
Aftermarket and End-Market Mix Progress
Aftermarket revenue as a percent of BSI increased to 38% in 2025 (from 35% in 2024) and more than 60% of BSI revenue now aligned with Project Accelerate 3.0 focus areas (biopharma, diagnostics, semiconductor metrology).