Clinical TrialsThe BBI-355 (CHK1) / BBI-825 (RNR) combo arm in the POTENTIATE trial is open for enrollment, suggesting potential data in 2026.
Efficacy And SafetyCHK1i + RNRi could achieve meaningful efficacy at tolerable exposures, avoiding the tox ceiling that crippled prior CHK1s.
Financial OutlookThe company reported $127mn in cash reiterating runway into 1H28, and expects PoC clinical readouts for both programs within this timeline.