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Starpharma Holdings Limited (AU:SPL)
ASX:SPL
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Starpharma Holdings Limited (SPL) AI Stock Analysis

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AU:SPL

Starpharma Holdings Limited

(Sydney:SPL)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
AU$0.59
▲(54.21% Upside)
Action:Reiterated
Date:05/20/26
The score is primarily weighed down by weak financial performance, especially ongoing losses and negative operating/free cash flow, despite solid revenue growth and conservative leverage. Technicals are mixed: oversold signals are supportive, but the stock remains below its short-term moving average. Valuation appears demanding (P/E 27.578) given profitability and cash flow challenges.
Positive Factors
Proprietary Dendrimer Platform
Starpharma’s proprietary dendrimer technology is a durable competitive asset that supports multiple use cases (drug delivery, anti-infective, topical). A platform model fosters licensing, partnership and product revenue streams that can compound over 2–6 months as programs mature.
Negative Factors
Negative Cash Flow
Persistent negative operating and free cash flow indicate the company is burning cash to fund operations and development. This constrains its ability to self-fund programs, raises reliance on external capital, and can dilute shareholders or slow execution if financing conditions tighten.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary Dendrimer Platform
Starpharma’s proprietary dendrimer technology is a durable competitive asset that supports multiple use cases (drug delivery, anti-infective, topical). A platform model fosters licensing, partnership and product revenue streams that can compound over 2–6 months as programs mature.
Read all positive factors

Starpharma Holdings Limited (SPL) vs. iShares MSCI Australia ETF (EWA)

Starpharma Holdings Limited Business Overview & Revenue Model

Company Description
Starpharma Holdings Limited (SPL) is an Australian biotechnology company focused on the development of innovative drug delivery systems and new therapeutic products. The company specializes in dendrimer technology, which allows for enhanced delive...
How the Company Makes Money
Starpharma makes money primarily through (1) licensing and collaboration revenues tied to its dendrimer technology (including payments such as upfront fees, milestone payments, and royalties when partners commercialize products that use the techno...

Starpharma Holdings Limited Financial Statement Overview

Summary
Revenue growth is positive (+18.13%), but profitability remains weak with negative EBIT and net margins. Balance sheet leverage is conservative (low debt-to-equity) but returns are poor (negative ROE). Cash flow is the main drag, with negative operating and free cash flow and weak cash conversion.
Income Statement
45
Neutral
Balance Sheet
50
Neutral
Cash Flow
40
Negative
BreakdownTTMJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue14.26M4.91M8.29M2.94M4.68M1.80M
Gross Profit8.57M3.69M7.66M1.22M1.91M539.50K
EBITDA-8.00M-10.93M-9.63M-22.08M-22.34M-26.05M
Net Income-3.23M-9.99M-8.16M-15.64M-16.15M-19.73M
Balance Sheet
Total Assets26.17M25.42M36.81M52.09M66.17M73.24M
Cash, Cash Equivalents and Short-Term Investments18.25M15.41M23.36M35.18M49.92M60.50M
Total Debt790.00K2.40M3.53M8.27M8.19M1.17M
Total Liabilities4.69M6.42M8.70M17.27M17.78M10.94M
Stockholders Equity21.48M19.00M28.12M34.81M48.39M62.30M
Cash Flow
Free Cash Flow-1.10M-6.80M-7.07M-14.15M-14.00M-15.05M
Operating Cash Flow-852.00K-6.76M-6.98M-13.53M-13.16M-14.81M
Investing Cash Flow-248.00K-42.00K-89.00K-610.00K-836.00K-246.00K
Financing Cash Flow-870.00K-1.13M-4.75M-695.00K3.23M46.30M

Starpharma Holdings Limited Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.38
Price Trends
50DMA
0.59
Positive
100DMA
0.49
Positive
200DMA
0.38
Positive
Market Momentum
MACD
<0.01
Positive
RSI
43.96
Neutral
STOCH
18.98
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:SPL, the sentiment is Positive. The current price of 0.38 is below the 20-day moving average (MA) of 0.70, below the 50-day MA of 0.59, and above the 200-day MA of 0.38, indicating a neutral trend. The MACD of <0.01 indicates Positive momentum. The RSI at 43.96 is Neutral, neither overbought nor oversold. The STOCH value of 18.98 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for AU:SPL.

Starpharma Holdings Limited Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
AU$256.77M27.58-15.96%364.97%74.50%
45
Neutral
AU$68.10M-2.00-131.13%2086.71%-116.20%
44
Neutral
AU$123.08M-5.17-278.87%1219.92%38.88%
42
Neutral
AU$86.95M-3.40-69.20%-73.11%
41
Neutral
AU$141.70M-2.84279.21%-37.23%
41
Neutral
AU$38.65M-10.60-142.30%-45.25%40.54%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:SPL
Starpharma Holdings Limited
0.62
0.53
615.12%
AU:IMM
Immutep Ltd
0.06
-0.24
-79.66%
AU:DXB
Dimerix Limited
0.20
-0.38
-65.52%
AU:ADO
AnteoTech Ltd
0.02
<0.01
70.00%
AU:BOT
Botanix Pharmaceuticals Limited
0.02
-0.35
-93.60%
AU:RCE
Recce Pharmaceuticals Ltd.
0.51
0.21
71.19%

Starpharma Holdings Limited Corporate Events

Starpharma Wins FDA Backing for DEP HER2 Trial as Partnerships and Product Sales Advance
Apr 29, 2026
Starpharma reported strong operational momentum in the March quarter, highlighted by U.S. FDA alignment on the first-in-human phase 1 trial design for its DEP&#174; HER2 radiotherapeutic, a targeted lutetium-177 dendrimer conjugate for advanced HE...
Starpharma Secures FDA Backing for DEP HER2 First-in-Human Trial Pathway
Apr 21, 2026
Starpharma has received positive guidance from the U.S. FDA on the clinical development strategy and first-in-human phase 1 trial design for its DEP HER2 radiotherapy candidate, a dendrimer-based conjugate targeting HER2 receptors with a lutetium-...
Starpharma Seeks ASX Quotation for Over 1 Million New Shares
Apr 6, 2026
Starpharma Holdings Limited has applied to the ASX for quotation of 1,012,747 new fully paid ordinary shares under the code SPL, issued on 11 March 2026 following the exercise or conversion of existing options or other convertible securities. The ...
UBS Group Ceases to Be Substantial Shareholder in Starpharma
Mar 12, 2026
UBS Group AG and its related bodies corporate have notified Starpharma Holdings Limited that they have ceased to be a substantial shareholder in the company as of 10 March 2026. The change in UBS&#8217;s relevant interest in Starpharma&#8217;s vot...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 20, 2026