FDA Approval of Rodemplo
Arrowhead Pharmaceuticals announced FDA approval of Rodemplo as an adjunct to diet to reduce triglycerides in adults with familial chylomicronemia syndrome (FCS), marking its first FDA-approved medicine and transition to a commercial stage.
Robust Financial Performance
Arrowhead Pharmaceuticals reported a near breakeven result with a net loss of $2 million for fiscal year 2025, significantly improved from a net loss of $599 million in fiscal year 2024, driven by $829 million in revenue from license and collaboration agreements.
Significant Milestone Payments
The company earned a $200 million milestone payment from Sarepta and a $200 million upfront payment from Novartis for licensing collaboration agreements, along with potential future milestone payments of up to $2 billion.
Pipeline Advancements
Progress in pipeline programs including Phase III trials for Zidaziran and Aerodimer PA, and expansion into CNS with ARO MAPT for tauopathies and Alzheimer's disease, demonstrating a broad and diverse pipeline.