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Arrowhead Pharmaceuticals, Inc. (ARWR)
NASDAQ:ARWR
US Market
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Arrowhead Pharmaceuticals (ARWR) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
Aug 06, 2026
After Close (Confirmed)
Period Ending
2026 (Q3)
Consensus EPS Forecast
-1.2
Last Year’s EPS
-1.26
Same Quarter Last Year
Based on 10 Analysts Ratings

Earnings Call Summary

Q2 2026
Earnings Call Date:May 07, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
Overall the call conveyed a constructive and growth-oriented tone: the REDEMPLO launch is exceeding early expectations with accelerating prescriptions, the company has a broad and innovative clinical pipeline with several near-term catalyst readouts, and a materially strengthened balance sheet provides capital flexibility. Counterbalancing this are the early-stage/commercial sales (net product sales ~ $1M), a quarterly net loss driven by elevated R&D/SG&A spend and dependence on upcoming pivotal readouts for label expansion and commercial scale. On balance, the positives (strong launch momentum, compelling efficacy data to date, global approvals, and significant funding) outweigh the near-term financial and clinical risks.
Company Guidance
Arrowhead provided detailed near‑term guidance and timelines with many specific metrics: REDEMPLO (FDA approved 11/18/2025 for FCS, ~6,500 U.S. patients) has >400 prescriptions since launch (~30 new scripts/week), prescriptions grew nearly threefold over the quarter and >40% in the last 4 weeks, ~85% of scripts are APOC3‑naive and >10% are switchers; U.S. WAC was set at $45,000/year (down from $60,000), competitor pricing noted at $40,000; regulatory approvals secured in Australia, China and Canada and a CHMP positive opinion with an EMA decision expected June–July and launches planned later in 2026 (Canada, select EU/U.K.; China to be marketed by Sanofi). Key clinical milestones: pooled SHASTA‑3/SHASTA‑4 (>750 patients) and MUIR‑3 (>1,400 patients) are on track for top‑line readouts in Q3 2026 to support an sNDA before year‑end and a potential approval in H2 2027; 2‑year open‑label plozasiran data showed median TG reductions of 83% (SHTG) and 67% (HTG), 96% of SHTG patients <500 mg/dL and 63% <150 mg/dL, with no adjudicated acute pancreatitis events; ARO‑DIMER‑PA (Phase I/II up to 78 subjects) first readout expected Q3 2026; ARO‑MAPT (Phase I/II up to 64 healthy + up to 48 AD patients) initial data expected end‑Q3/early‑Q4 2026; ARO‑INHBE and ARO‑ALK7 updates planned in H2 2026; YOSEMITE (zodasiran ~60 HoFH patients) on track for full enrollment in 2026 and potential NDA filings by end‑2027. Financial/portfolio metrics: Q2 FY2026 net loss $132.7M, loss per share $0.93 on 142.4M diluted avg shares, revenue $74M (≈$42M Sarepta, $20M Novartis recognized, YTD Novartis recognition $54M), operating expenses ≈$215M (R&D +$40M YOY, SG&A +$13M YOY), cash & investments ≈$1.8B as of 3/31/2026, common shares outstanding 140.6M, completed concurrent financings of $700M 0% convertible notes and $230M common stock (net ≈$850M in the quarter), and a license to Madrigal for ARO‑PNPLA3 with $25M upfront, up to $975M in milestones and tiered mid‑teens royalties.
Strong REDEMPLO Launch Momentum
FDA-approved REDEMPLO launched in Nov 2025 and continues to accelerate: ~30 new prescriptions/week with >400 prescriptions written since launch; prescriptions grew nearly threefold from the start to the end of the fiscal quarter and >40% growth over the most recent 4-week period. Patient mix: ~85% APOC3-class naive; >10% of prescriptions are switches from a competitor.
Clinical Efficacy Signals for Plozasiran
2-year open-label extension data: median triglyceride reductions of 83% in SHTG (SHASTA-2) and 67% in HTG (MUIR); 96% of SHTG patients achieved TG <500 mg/dL, 63% achieved TG <150 mg/dL, and 93% of HTG patients achieved TG <150 mg/dL. No adjudicated acute pancreatitis events observed in patients receiving plozasiran during the 2-year OLE.
Multiple Near-Term Clinical Catalysts
Several important readouts expected in 2H 2026: SHASTA-3 and -4 top-line Phase III plozasiran data (Q3) to support an sNDA for SHTG; first clinical readout of ARO-DIMER-PA (dual siRNA) in Q3; initial ARO-MAPT CNS platform data end of Q3/early Q4; ongoing updates for ARO-INHBE and ARO-ALK7 across H2 2026.
Broad and Innovative Pipeline Expansion
Pipeline exceeds 20 clinical programs across liver, muscle, adipose, CNS and lung, including the first-in-human dual functional siRNA (ARO-DIMER-PA) and a proprietary CNS delivery candidate (ARO-MAPT) designed for subcutaneous delivery across the BBB; expectation of additional dual-dimer candidates in 2027.
Global Regulatory Progress
REDEMPLO approvals in Australia, China and Canada and CHMP positive opinion recommending EU approval; anticipated launches later in 2026 in Canada, select EU countries and the U.K.; Greater China commercialization via Sanofi.
Material Balance Sheet Strengthening
Completed largest fundraising in company history: concurrent public offerings of $700M 0% convertible senior notes and $230M common stock (both several times oversubscribed). Cash and investments nearly $1.8B as of March 31, 2026; brought in over $1B in the quarter including ~$850M net from financing and milestone/payments from partners.
Strategic Business Development
Exclusive license agreement with Madrigal for ARO-PNPLA3: $25M upfront, up to $975M in development/regulatory/sales milestones, plus tiered royalties up to mid-teens; additional ongoing collaborations with Sarepta and Novartis contributing revenue recognition.
Early Commercial and Payer Dynamics Positive
Updated WAC to $45,000/year aimed at simplifying pricing across indications; company reports generally positive payer interactions and emerging coverage policies that accept both genetic and clinical diagnostic pathways for FCS.

Arrowhead Pharmaceuticals (ARWR) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

ARWR Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
Aug 06, 2026
2026 (Q3)
-1.20 / -
-1.26
May 07, 2026
2026 (Q2)
-1.09 / -0.93
2.75-133.82% (-3.68)
Feb 05, 2026
2026 (Q1)
0.04 / 0.22
-1.39115.83% (+1.61)
Nov 25, 2025
2025 (Q4)
-0.11 / -0.11
-1.3691.91% (+1.25)
Aug 07, 2025
2025 (Q3)
-0.95 / -1.26
-1.388.70% (+0.12)
May 12, 2025
2025 (Q2)
-0.19 / 2.75
-1.02369.61% (+3.77)
Feb 10, 2025
2025 (Q1)
-0.48 / -1.39
-1.24-12.10% (-0.15)
Nov 26, 2024
2024 (Q4)
-1.12 / -1.36
-1.02-33.33% (-0.34)
Aug 08, 2024
2024 (Q3)
-0.53 / -1.38
-0.96-43.75% (-0.42)
May 09, 2024
2024 (Q2)
-0.47 / -1.02
0.45-326.67% (-1.47)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

ARWR Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
May 07, 2026
$77.95$72.69-6.75%
Feb 05, 2026
$64.64$64.52-0.19%
Nov 25, 2025
$46.79$57.71+23.34%
Aug 07, 2025
$16.06$16.42+2.24%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Arrowhead Pharmaceuticals, Inc. (ARWR) report earnings?
Arrowhead Pharmaceuticals, Inc. (ARWR) is schdueled to report earning on Aug 06, 2026, After Close (Confirmed).
    What is Arrowhead Pharmaceuticals, Inc. (ARWR) earnings time?
    Arrowhead Pharmaceuticals, Inc. (ARWR) earnings time is at Aug 06, 2026, After Close (Confirmed).
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          What is ARWR EPS forecast?
          ARWR EPS forecast for the fiscal quarter 2026 (Q3) is -1.2.