ALTO-207 Acquisition And TolerabilityThe acquisition of ALTO-207, combining pramipexole with ondansetron, builds on promising treatment-resistant depression signals and is designed to mitigate dose-limiting side effects, potentially enabling wider and more sustained patient use.
Biomarker-driven Patient SelectionAlto's biomarker-driven precision psychiatry platform can identify patient subgroups most likely to respond to specific drug mechanisms, increasing the likelihood of clinical trial success and a more differentiated drug label.
Upcoming Clinical Readouts And Program ValidationA near-term mid-stage readout for ALTO-300 along with multiple additional program results present opportunities to demonstrate efficacy, strengthen regulatory momentum, and increase investor interest.