Want to see ANRO full AI Analyst Report?
ANRO Stock Chart & Stats
$27.72
-$0.09(-1.99%)
At close: 4:00 PM EST
$27.72
-$0.09(-1.99%)
Day’s Range― - ―
52-Week Range$2.20 - $28.44
Previous CloseN/A
Volume104.17K
Average Volume (3M)2.30M
Market Cap
$926.13M
Enterprise Value$506.63M
Total Cash (Recent Filing)$263.76M
Total Debt (Recent Filing)$5.69M
Price to Earnings (P/E)―
Beta2.08
Next Earnings
Aug 19, 2026EPS Estimate
-0.72Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-2.48
Shares Outstanding35,093,940
10 Day Avg. Volume557,199
30 Day Avg. Volume2,303,174
Financial Highlights & Ratios
PEG Ratio0.66
Price to Book (P/B)3.40
Price to Sales (P/S)0.00
P/FCF Ratio-9.92
Enterprise Value/Market Cap0.55
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-1.78K
Enterprise Value/Ebitda-7.11
Forecast
1Y Price Target
$34.78Price Target Upside25.46% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering11
EPS Forecast (FY)-2.98
Revenue Forecast (FY)N/A
Bulls Say, Bears Say
Bulls Say
Biomarker-driven Precision PlatformAlto's biomarker-driven approach is a durable competitive advantage in neuropsychiatry: stratifying patients reduces heterogeneity in trials, improves signal detection, and increases the odds of clinical success. Over 2–6 months this supports partner interest and more efficient development paths.
Low Leverage, Strong CapitalizationA low-debt balance sheet materially reduces near-term insolvency risk and preserves optionality. With modest leverage and improved equity capitalization, Alto can fund near-term trials, pursue partnerships on better terms, and avoid urgent dilutive financings while advancing lead programs.
Board Expertise EnhancedAdding an experienced biotech leader to the board strengthens governance and strategic execution. Miller's drug-development and corporate strategy background can improve program prioritization, partner negotiations, and operational oversight—benefits that persist across clinical cycles.
Bears Say
Pre-revenue With Widening LossesAlto remains pre-revenue with losses that more than doubled TTM versus 2023, reflecting increasing R&D spend without offsetting income. This structural deficit increases likelihood of future financing, dilutive capital raises, and constrains long-term return prospects absent clinical success or partnership monetization.
Persistent Heavy Cash BurnSustained negative operating and free cash flow at scale creates ongoing runway pressure. Even with low debt, continued burn forces strategic tradeoffs: pausing programs, accelerating partner deals, or raising capital—each of which can dilute shareholders or slow development progress over the next several quarters.
Clinical Setback And Pipeline ConcentrationA Phase 2 miss for ALTO-101 and the decision to seek partners while reallocating to ALTO-207 concentrates clinical risk into the lead program. Dependence on a single Phase 2b entry increases binary outcome risk; failure or delay in ALTO-207 would materially impair value creation and strategic momentum.
ANRO FAQ
What was Alto Neuroscience, Inc.’s price range in the past 12 months?
Alto Neuroscience, Inc. lowest stock price was $2.20 and its highest was $28.44 in the past 12 months.
What is Alto Neuroscience, Inc.’s market cap?
Alto Neuroscience, Inc.’s market cap is $926.13M.
When is Alto Neuroscience, Inc.’s upcoming earnings report date?
Alto Neuroscience, Inc.’s upcoming earnings report date is Aug 19, 2026 which is in 49 days.
How were Alto Neuroscience, Inc.’s earnings last quarter?
Alto Neuroscience, Inc. released its earnings results on May 13, 2026. The company reported -$0.8 earnings per share for the quarter, missing the consensus estimate of -$0.536 by -$0.264.
Is Alto Neuroscience, Inc. overvalued?
According to Wall Street analysts Alto Neuroscience, Inc.’s price is currently Undervalued.
Does Alto Neuroscience, Inc. pay dividends?
Alto Neuroscience, Inc. does not currently pay dividends.
What is Alto Neuroscience, Inc.’s EPS estimate?
Alto Neuroscience, Inc.’s EPS estimate is -0.72.
How many shares outstanding does Alto Neuroscience, Inc. have?
Alto Neuroscience, Inc. has 35,093,940 shares outstanding.
What happened to Alto Neuroscience, Inc.’s price movement after its last earnings report?
Alto Neuroscience, Inc. reported an EPS of -$0.8 in its last earnings report, missing expectations of -$0.536. Following the earnings report the stock price went down -7.227%.
Which hedge fund is a major shareholder of Alto Neuroscience, Inc.?
Currently, no hedge funds are holding shares in ANRO
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Alto Neuroscience, Inc. Stock Smart Score
Outperform
1
2
3
4
5
6
7
8
9
10
Analyst Consensus
Strong Buy
Average Price Target:
$34.78 (25.46% Upside)
$34.78 (25.46% Upside)
Hedge Fund Trend
Increased
By 358.9K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Very Negative
Last 7 Days ▼ 0.9%
Last 30 Days ▼ 2.9%
Last 30 Days ▼ 2.9%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Positive
20 days / 200 days
Momentum
-57.39%
12-Months-Change
Fundamentals
Return on Equity
-47.22%
Trailing 12-Months
Asset Growth
60.70%
Trailing 12-Months
Company Description
Alto Neuroscience, Inc.
Alto Neuroscience, Inc. operates as a biopharmaceutical entity in the clinical stage, specializing in the creation of novel psychiatric medications. Its development pipeline includes ALTO-100, an investigational therapy targeting individuals affected by major depressive disorder (MDD) and post-traumatic stress disorder. Also in its portfolio is ALTO-300, a small molecule designed to function as both a melatonergic agonist and serotonergic antagonist, exhibiting antidepressant properties for MDD patients. For addressing the cognitive impairments linked with schizophrenia, Alto Neuroscience is advancing ALTO-101, an innovative small molecule phosphodiesterase 4 inhibitor. The company's therapeutic candidates further extend to ALTO-203, a pioneering small-molecule histamine H3 receptor inverse agonist intended for MDD patients experiencing heightened anhedonia, and ALTO-202, an orally available antagonist of the GluN2B subunit of the NMDA receptor, also under investigation for MDD. Beyond these individual drug candidates, the firm is engaged in developing novel drug combinations that demonstrate synergistic pharmacodynamic effects. Crucially, Alto Neuroscience leverages an advanced AI-enabled biomarker platform that synthesizes data concerning patients' brain activity and behavioral patterns. This platform's purpose is to accurately identify which individuals are most likely to respond positively to its cutting-edge product candidates. Alto Neuroscience, Inc., established in 2019, maintains its headquarters in Los Altos, California.
ANRO Stock 12 Month Forecast
Average Price Target
$34.78
▲(25.46% Upside)
Technical Analysis
―
Corbus Pharmaceuticals
―
Forte Biosciences
―
Milestone Pharmaceuticals
―
Elicio Therapeutics
―
Ownership Overview
4.67% Insiders
6.36% Mutual Funds
53.75% Other Institutional Investors
27.28% Public Companies and
Individual Investors










