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Allogene Therapeutics Inc (ALLO)
NASDAQ:ALLO
US Market

Allogene Therapeutics (ALLO) Earnings Dates, Call Summary & Reports

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Earnings Data

Report Date
May 06, 2026
Before Open (Confirmed)
Period Ending
2026 (Q1)
Consensus EPS Forecast
-0.19
Last Year’s EPS
-0.28
Same Quarter Last Year
Based on 9 Analysts Ratings

Earnings Call Summary

Q4 2025
Earnings Call Date:Mar 12, 2026|
% Change Since:
|
Earnings Call Sentiment|Positive
The call presented multiple high-impact near-term catalysts (April MRD readout for ALPHA-3 and June proof-of-concept data for ALLO-329), a differentiated autoimmune approach with potential low/no lymphodepletion, and an extended cash runway into 2028 to support prioritized programs. However, the company faces meaningful financial losses, dependence on surrogate MRD endpoints with incomplete linkage to clinical outcomes, competitive headwinds from frontline bispecifics, and uncertainty around safety and small-sample interim analyses. On balance, the call emphasized execution readiness and funding to reach key inflection points while acknowledging important clinical and market risks.
Company Guidance
The company reiterated financial and clinical guidance: as of 12/31/2025 cash, cash equivalents and investments were $258.3M, plus an additional $23.7M received from escrow in February and $20.7M raised year-to-date via ATM, extending runway into 2028 (said to cover ALPHA-3 enrollment); Q4 R&D was $28.6M (including $2.5M non‑cash stock‑based compensation) and FY R&D was $150.2M (incl. $12.9M SBC); Q4 G&A was $13.8M (incl. $5.6M SBC) and FY G&A was $56.8M (incl. $24.7M SBC); net loss Q4 was $38.8M or $0.17/sh and net loss FY was $190.9M or $0.87/sh (incl. $37.6M SBC and $2.4M impairment). For 2026 they guided operating cash expense of ~ $150M and GAAP operating expenses of ~ $210M (including ~ $35M non‑cash SBC), excluding BD impacts. Key clinical milestones: an ALPHA‑3 interim futility MRD analysis in April on 24 patients (12 per arm) with an anchored target 25–30 percentage‑point absolute delta in MRD clearance, >60 active U.S./Canada sites (Australia and South Korea start‑ups underway) and modeled spontaneous MRD clearance of ~20% in the observation arm; and ALLO‑329 proof‑of‑concept translational and early clinical signals expected in June 2026 from the RESOLUTION Phase 1 (3+3) study starting at 20M CAR T cells in parallel cohorts with cyclophosphamide‑only and no lymphodepletion (noting competitor doses up to ~5–10x autologous and ~50x other allogeneic).
Upcoming Clinical Catalysts and Timelines
ALPHA-3 (SemiCell) interim futility MRD analysis planned for April 2026 on 24 patients (12 per arm); ALLO-329 proof-of-concept translational and early clinical signals expected in June 2026; additional clinical updates anticipated later in 2026.
Ambitious MRD Efficacy Target for ALPHA-3
Company anchored expectations around a 25% to 30% absolute delta in MRD clearance between SemiCell-treated and observation arms—a threshold management calls potentially practice-changing for first-line large B-cell lymphoma.
Broad Clinical Footprint for SemiCell
SemiCell is active in over 60 clinical sites across the U.S. and Canada with site start-up activities underway in Australia and South Korea, emphasizing community integration and outpatient delivery as a strategic advantage of the off-the-shelf model.
ALLO-329 Differentiated Autoimmune Program
ALLO-329 is a dual CD19/CD70 allogeneic CAR T designed with Dagger technology to enable in vivo expansion at low cell doses; study starts at 20 million CAR-T cells (significantly lower than competitors—autologous programs 5x–10x higher, other allogeneic programs up to ~50x higher); cohorts include cyclophosphamide-only and no lymphodepletion to test low/no lymphodepletion feasibility.
Extended Cash Runway into 2028
As of 12/31/2025 cash, cash equivalents, and investments were $258.3 million; company received an additional $23.7 million from escrow in February and raised $20.7 million YTD via ATM, extending runway into 2028 to support completion of ALPHA-3 enrollment.
Focused Prioritization and Capital Allocation
Management has prioritized resources behind ALPHA-3 and RESOLUTION (ALLO-329), highlighting discipline in advancing high-impact programs and explicitly linking cash runway to execution of these pivotal studies.
Clear Financial Guidance for 2026
Guidance provided: operating cash expense ~ $150 million for 2026; GAAP operating expenses ~ $210 million including estimated ~$35 million of non-cash stock-based compensation—giving investors visibility into near-term burn and planning assumptions.

Allogene Therapeutics (ALLO) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

ALLO Earnings History

Report Date
Fiscal Quarter
Forecast / EPS
Last Year's EPS
EPS YoY Change
Press Release
Slides
Play Transcript
May 06, 2026
2026 (Q1)
-0.19 / -
-0.28
Mar 12, 2026
2025 (Q4)
-0.23 / -0.17
-0.2839.29% (+0.11)
Nov 06, 2025
2025 (Q3)
-0.22 / -0.19
-0.3240.63% (+0.13)
Aug 13, 2025
2025 (Q2)
-0.27 / -0.23
-0.3534.29% (+0.12)
May 13, 2025
2025 (Q1)
-0.29 / -0.28
-0.3826.32% (+0.10)
Mar 13, 2025
2024 (Q4)
-0.33 / -0.28
-0.5145.10% (+0.23)
Nov 07, 2024
2024 (Q3)
-0.33 / -0.32
-0.3713.51% (+0.05)
Aug 07, 2024
2024 (Q2)
-0.35 / -0.35
-0.5333.96% (+0.18)
May 13, 2024
2024 (Q1)
-0.41 / -0.38
-0.6844.12% (+0.30)
Mar 14, 2024
2023 (Q4)
-0.45 / -0.51
-0.6622.73% (+0.15)
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
Beat
Missed

ALLO Earnings-Related Price Changes

Report Date
Price 1 Day Before
Price 1 Day After
Percentage Change
Mar 12, 2026
$2.47$2.40-2.83%
Nov 06, 2025
$1.05$1.18+12.38%
Aug 13, 2025
$1.04$1.07+2.88%
May 13, 2025
$1.13$0.95-15.93%
Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Allogene Therapeutics Inc (ALLO) report earnings?
Allogene Therapeutics Inc (ALLO) is schdueled to report earning on May 06, 2026, Before Open (Confirmed).
    What is Allogene Therapeutics Inc (ALLO) earnings time?
    Allogene Therapeutics Inc (ALLO) earnings time is at May 06, 2026, Before Open (Confirmed).
      Where can I see when companies are reporting earnings?
      You can see which companies are reporting today on our designated earnings calendar.
        What companies are reporting earnings today?
        You can see a list of the companies which are reporting today on TipRanks earnings calendar.
          What is ALLO EPS forecast?
          ALLO EPS forecast for the fiscal quarter 2026 (Q1) is -0.19.