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Akari Therapeutics PLC (ADR) (AKTX)
:AKTX
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Akari Therapeutics (AKTX) AI Stock Analysis

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AKTX

Akari Therapeutics

(NASDAQ:AKTX)

Rating:44Neutral
Price Target:
Akari Therapeutics' stock score of 44 reflects significant challenges due to its current financial instability and lack of revenue. While the technical analysis indicates a neutral trend, the company's speculative nature due to the absence of traditional valuation metrics underscores the risk. However, the recent positive corporate event with the appointment of a new CEO brings some potential for strategic improvement, slightly offsetting the otherwise high-risk profile.
Positive Factors
Analyst Recommendation
Analyst recommendation is a Buy for Akari Therapeutics stock.
Innovative Technology
Akari Therapeutics is using a novel payload approach in the high-value ADC space.
Pipeline Potential
The key is the departure from toxin-based payloads, along with validated targets could make the Akari pipeline attractive for potential partners.
Negative Factors
Preclinical Stage
PH1-ADCs in preclinical work have demonstrated synergy with checkpoint inhibitors and offer a more favorable toxicity profile, which suggests potential higher therapeutic index.

Akari Therapeutics (AKTX) vs. SPDR S&P 500 ETF (SPY)

Akari Therapeutics Business Overview & Revenue Model

Company DescriptionAkari Therapeutics, Plc, a clinical-stage biopharmaceutical company, focuses on developing advanced therapies for autoimmune and inflammatory diseases. Its lead product candidate is nomacopan, a second-generation complement inhibitor that prevents inflammatory and prothrombotic activities, including paroxysmal nocturnal hemoglobinuria, Guillain-Barré syndrome, hematopoietic stem cell transplant-associated thrombotic microangiopathy, and bullous pemphigoid. Akari Therapeutics, Plc is based in London, the United Kingdom.
How the Company Makes MoneyAkari Therapeutics primarily makes money through the development and commercialization of its proprietary drug candidates. The company generates revenue through partnerships, licensing agreements, and potential sales of its therapeutic products upon receiving regulatory approval. Key revenue streams include milestone payments and royalties from strategic collaborations with larger pharmaceutical companies that have the resources to bring Akari's products to market. Additionally, Akari may receive research and development funding from grants or governmental and non-governmental organizations, supporting its ongoing drug development efforts.

Akari Therapeutics Financial Statement Overview

Summary
Akari Therapeutics is in an early-stage biotechnology phase with no revenue generation and consistent losses, leading to negative cash flow and reliance on external financing. While the company's debt levels are low, the financial instability is evident from the fluctuating equity and persistent cash burn. Sustained financial health will depend on successful product development and commercialization to transition from a loss-making to a revenue-generating entity.
Income Statement
15
Very Negative
Akari Therapeutics has not generated any revenue over the past years, which is typical for early-stage biotechnology companies but poses a significant risk in terms of financial sustainability. The company reports consistent negative EBIT and net income, indicating ongoing operational losses without any top-line growth. The inability to generate revenue while incurring significant expenses results in a challenging financial position.
Balance Sheet
40
Negative
Despite having no revenue, Akari Therapeutics maintains a relatively low level of debt compared to its equity, demonstrating prudent capital management. However, stockholders' equity has fluctuated, with a substantial deficit in 2023, which indicates financial instability. The equity ratio remains modest, reflecting a need for improved financial performance to stabilize the balance sheet.
Cash Flow
20
Very Negative
The company has experienced negative operating cash flow consistently, signaling cash burn due to lack of revenue. Although financing cash flow has supported operations through equity raises or debt, the free cash flow remains negative, highlighting the dependency on external financing to sustain operations. This situation underscores the high risk of cash flow shortages if financing becomes constrained.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit0.00
EBITDA-21.64M-16.80M-23.08M-17.21M-20.44M
Net Income-19.79M-10.01M-6.97M-17.61M-17.60M
Balance Sheet
Total Assets50.56M4.36M13.83M11.65M17.59M
Cash, Cash Equivalents and Short-Term Investments2.60M3.85M13.25M9.36M14.06M
Total Debt3.26M0.000.000.000.00
Total Liabilities28.33M4.58M12.04M6.09M5.22M
Stockholders Equity22.23M-229.00K1.79M5.55M12.38M
Cash Flow
Free Cash Flow-12.55M-16.43M-21.50M-18.85M-16.95M
Operating Cash Flow-12.55M-16.43M-21.50M-18.85M-16.95M
Investing Cash Flow382.00K0.000.000.000.00
Financing Cash Flow10.99M7.02M25.29M14.29M25.07M

Akari Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.14
Price Trends
50DMA
1.21
Negative
100DMA
1.21
Negative
200DMA
1.40
Negative
Market Momentum
MACD
-0.02
Negative
RSI
47.08
Neutral
STOCH
80.95
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AKTX, the sentiment is Negative. The current price of 1.14 is above the 20-day moving average (MA) of 1.14, below the 50-day MA of 1.21, and below the 200-day MA of 1.40, indicating a neutral trend. The MACD of -0.02 indicates Negative momentum. The RSI at 47.08 is Neutral, neither overbought nor oversold. The STOCH value of 80.95 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AKTX.

Akari Therapeutics Risk Analysis

Akari Therapeutics disclosed 61 risk factors in its most recent earnings report. Akari Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Akari Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$38.41M-73.11%-60.20%3.85%
52
Neutral
kr5.63B10.07-63.86%1.97%27.19%26.73%
45
Neutral
$45.62M-75.66%-31.16%
44
Neutral
$31.76M-197.11%
44
Neutral
$8.68M0.67121.75%
42
Neutral
$39.26M-71.90%69.65%27.98%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AKTX
Akari Therapeutics
1.10
-3.15
-74.12%
XFOR
X4 Pharmaceuticals
1.83
-24.03
-92.92%
LTRN
Lantern Pharma
4.26
-0.32
-6.99%
STTK
Shattuck Labs
0.87
-3.54
-80.27%
LVTX
LAVA Therapeutics
1.46
-0.61
-29.47%

Akari Therapeutics Corporate Events

Executive/Board ChangesBusiness Operations and Strategy
Akari Therapeutics Appoints New CEO Abizer Gaslightwala
Positive
Mar 20, 2025

On March 14, 2025, Akari Therapeutics announced the appointment of Mr. Abizer Gaslightwala as the new President and Chief Executive Officer, effective April 21, 2025. Mr. Gaslightwala, who has a robust background in the pharmaceutical industry with leadership roles at Jazz Pharmaceuticals, Amgen, and Pfizer, will replace Dr. Samir R. Patel, who will step down on April 14, 2025, but remain on the board. This leadership change is expected to bring strategic insights and strengthen Akari’s market position in the biopharmaceutical sector.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 20, 2025