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Akari Therapeutics PLC (ADR) (AKTX)
NASDAQ:AKTX
Nomacopan (Rva576)
Bullous Pemphigoid
Phase III
Withdrawn
Nomacopan Therapy in Adult Patients With Bullous Pemphigoid Receiving Adjunct Oral Corticosteroid Therapy (ARREST-BP)
Sep 15, 2021
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Nomacopan (Rva576)
Thrombotic Microangiopathies
Phase III
Terminated
Nomacopan (rVA576) in Transplant Associated Thrombotic Microangiopathy
Nov 19, 2020
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Rva576
Bullous Pemphigoid (Bp)
Phase II
Completed
rVA576 in Adult Mild to Moderate Bullous Pemphigoid Subjects
Apr 12, 2019
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Rva576
Conjunctivitis, Allergic, Keratoconjunctivitis, Atopic, Keratoconjunctivitis, Vernal
Phase I/II
Terminated
Topical rVA576 for Treatment of Atopic Keratoconjunctivitis
Feb 13, 2019
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Rva576
Paroxysmal Nocturnal Hemoglobinuria
Phase III
Terminated
rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study
Dec 20, 2018
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Standard Of Care (Soc), Rva576
Paroxysmal Nocturnal Hemoglobinuria (Pnh)
Phase III
Completed
Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576
Jun 01, 2018
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Coversin
Paroxysmal Nocturnal Hemoglobinuria (Pnh)
Phase II
Completed
Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms
Jan 24, 2018
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Akari Therapeutics PLC (ADR) (AKTX) have in its pipeline
AKTX is currently developing the following drugs: Nomacopan (Rva576), Nomacopan (Rva576), Rva576. These drug candidates are in various stages of clinical development as the company works toward FDA approval.