Adverse EventsThree deaths occurred due to adverse events, highlighting potential risks despite the positive outcomes.
Clinical ExperienceMore cautious investor inbounds point toward relatively limited clinical experience with anito-cel thus far.
Manufacturing And Supply IssuesLegend / JnJ changed CARVYKTI release specifications during development, contributing to higher manufacturing failure rates, and exacerbating the supply shortage for JnJ/Legend's Carvykti.