Intellia Therapeutics' Promising Future: Buy Rating Backed by Strong Financials and Program AdvancementsNTLA's 4Q24 earnings report was straightforward, with key programs on track. On the TTR front, mgmt continues to guide to the enrollment of at least 550 pts by YE, despite the advancement of competitive TTR products in the field. With limited updates expected from the co's MAGNITUDE and MAGNITUDE-2 trials this year, we remain focused on the longer-term Ph1 data — expected to be presented in 2025 and includes both pt types — for readthrough to the pivotal Ph3s. On the HAE side, the co newly announced the successful dosing of its first pt in its Ph3 HAELO trial, and continues to guide to completing pt enrollment in 2H25. Outside of the pipeline, NTLA gave guidance on future OpEx expectations, citing a 5-10% yoy decline in 2025, followed by a steady state to 2027 where costs associated with the clinical trials are expected to decline.