Strong ARCALYST Revenue Growth
Net product revenue for ARCALYST reached $137.8 million in Q1 2025, a 75% year-over-year increase compared to Q1 2024. The company increased its 2025 net sales guidance from $560-$580 million to $590-$605 million.
Increased Prescriber Base
The number of new prescribers increased by approximately 300 in Q1 2025, one of the highest quarterly increases since launch.
Positive Financial Performance
Kiniksa reported a net income of $8.5 million in Q1 2025 compared to a net loss of $17.7 million in Q1 2024. ARCALYST collaboration profit grew 118% year-over-year to $87.6 million.
Extended Average Duration of Therapy
The average duration of therapy for ARCALYST increased from 27 months to 30 months.
Favorable Medicare Part D Changes
Federal changes to the Medicare Part D program improved patient affordability, leading to a onetime bolus of patients converting to paid therapy at the start of Q1 2025.