Strong Revenue Growth
Net product sales of $15.1M in Q1 2026 versus $8.8M in Q1 2025, representing ~73% year-over-year growth and marking the sixth consecutive quarter of increased net product sales since the new commercial leadership.
Fennec HEARS Operational Momentum
Completed infusions through the Fennec HEARS hub increased ~48% quarter-over-quarter; conversion rates into therapy hit the company's 80% benchmark for the first time and patient adherence is approximately 80%, a material improvement versus one year ago. April single-month HEARS demand exceeded 50% of total Q1 HEARS demand and Q2 demand is tracking to surpass Q1.
Commercial Expansion & Target Growth
Invested in 14 new territories and 4 frontline managers; prescriber target universe expanded from ~1,300 to over 5,000 targets (an increase of ~285%), enabling greater reach and frequency and early signs of new-account starts in April and balanced growth across academic and community settings.
Clinical & Investigator-Initiated Study Momentum
Announced a third investigator-initiated study (University of Arizona Cancer Center) in addition to earlier initiations at Tampa General Hospital Cancer Institute and City of Hope; these ISTs (plus ongoing studies) are generating clinical interest and early commercial adoption at participating institutions.
Peer Recognition and Scientific Visibility
Four abstracts evaluating PEDMARK for prevention of cisplatin-induced ototoxicity were accepted for presentation at the ASCO Annual Meeting, increasing scientific exposure and supporting potential broader clinical adoption.
Positive Regulatory Engagement in Japan
Held a positive informal meeting with Japan's PMDA and continue to explore partnering opportunities in the region, supporting potential international expansion efforts.
Positive Cash Flow and Balance Sheet Movement
Generated positive operating cash flow of $2.3M in the quarter; cash and cash equivalents increased by $3.3M to $40.1M as of March 31, 2026 (including ~$1M from option exercises). Company states cash, cash equivalents and investment securities plus projected PEDMARK revenues are sufficient to fund the business under the current plan.
Partnership Rollout Potential (PEDMARQSI / Norgine)
Expectation of a 2026 ramp in multiple markets through partner Norgine with royalty upside (mid-teens royalties referenced) and material milestone opportunity over time tied to sales, positioning a pathway for non-U.S. revenue growth.