Total Revenue Growth
Total revenue for Q1 2026 was approximately $11.5 billion, up 1% year-over-year, with management indicating the business is tracking toward the upper end of full-year guidance.
Growth Portfolio Performance
Growth portfolio sales increased 9% year-over-year to $6.2 billion, driven by a broad set of assets (Reblozyl, Breyanzi, Opdualag, Qvantig, Cobenfy and others) and described as in line with expectations.
Eliquis Strength
Eliquis revenue was approximately $4.1 billion in the quarter, up 13% year-over-year, reflecting continued strong demand despite U.S. list price reduction dynamics.
Breyanzi Momentum
Breyanzi recorded strong adoption with first-quarter growth of 53%, cited as reflecting best-in-class profile and continued strong demand across approved indications.
Reblozyl and Sotyktu Growth
Reblozyl grew 15% year-over-year with uptake across MDS-associated anemia lines; Sotyktu global revenue grew 20% with recent approval expansion into psoriatic arthritis.
Camzyos Rapid Adoption
Camzyos revenue nearly doubled to $314 million in Q1, with patient starts and persistency described as strong and roughly 25,000 U.S. patients prescribed to date.
Qvantig Commercial Traction
Qvantig (subcutaneous product) achieved over 10% conversion from IV to the auto-injector in the U.S. in just over a year; management expects ~30%–40% conversion of IV business over the next two years.
Pipeline and Regulatory Milestones
Key R&D achievements in Q1 include FDA acceptance of the iberdomide filing with Breakthrough Therapy designation and priority review (PDUFA Aug 17), positive Phase III interim PFS for mezignomide (SUCCESSR-II), positive Phase III interim topline ADC results in TNBC (China), multiple approvals (including additional Opdivo indications) and several positive Phase I/II/III readouts across programs.
R&D Productivity and Cost Savings Targets
Company is investing in R&D infrastructure and AI with a target to identify lead molecules ~50% faster and to reduce cycle times ~30% versus a few years ago; remains on track to deliver the remaining $2.0 billion in cost savings from its strategic productivity initiative by end of 2027.
Strong Balance Sheet and Cash Generation
As of March 31, cash and marketable securities were approximately $11 billion and operating cash flow was about $1.1 billion in Q1, supporting capital allocation flexibility, business development and dividends.