Successful Launch of O2VERE
O2VERE's launch for COPD treatment has doubled sales from Q4 2024 to Q1 2025, reaching $71.3 million with 25,000 prescriptions filled and a 50% increase in prescriber base.
Financial Performance Exceeds Expectations
For the first time, quarterly revenue exceeded operating expenses excluding noncash charges. Q1 2025 net revenue was $76.3 million, with an adjusted net income of $20.5 million.
Strong Financial Position
Cash and equivalents increased to $401.4 million by March 2025. Strategic financing arrangement with Oaktree and OMERS was amended, increasing the debt facility to $450 million on more favorable terms.
Expansion of O2VERE's Market
O2VERE was approved in Macau for COPD treatment, marking its first regulatory approval outside the US. Potential EU and UK marketing authorization applications are in progress.
Pipeline Advancements
Initiating a Phase 2b trial for a fixed-dose combination of ensifentrine and glycopyrrolate. Continued enrollment in a Phase 2 trial for nebulized ensifentrine in non-CF bronchiectasis.
New Patent for O2VERE
A new Orange Book listed patent was granted with an expiration date in 2044, enhancing the intellectual property protection for O2VERE.