Acquisition of Immunomodulatory Drug Candidate
Tivic Health Systems acquired worldwide exclusive rights to a phase three immunomodulatory drug candidate, Intellimod, from Staterra Biopharma, with rights to five additional indications and a second molecular structure, Entelasta. Over $140 million has been invested in development, and the drug aims to treat acute radiation syndrome (ARS), boasting a 3x increase in survival rates in animal models.
Strategic Transformation into a Diversified Therapeutics Company
The company is transitioning into a diversified therapeutic company with a robust pipeline combining biologic and bioelectronic medicine to focus on immune dysrhythmias, supported by the addition of former Staterra Biopharma CEO Michael K. Hanley as Chief Operating Officer.
Progress in Vagus Nerve Stimulation (VNS) Program
Tivic Health Systems is developing a noninvasive cervical vagus nerve stimulation device, showing a 400% increase in effects with personalized stimulation. This device aims to treat conditions like inflammatory, cardiac, and neurologic disorders without invasive surgeries.
NASDAQ Compliance and Financial Flexibility
The company expects to regain NASDAQ compliance with continued listing requirements and secured a $25 million equity line of credit to fund stages of development, potentially fully funding Intellimod's commercialization.