We thought the enrollment update was a big positive and shortened the timeline to a potential U.S. approval - which naturally and partially achieves the goal of the expedited development discussions. While STOK still plans to discuss an expedited pathway with FDA (Vineland-3 data being the main issue), it seems pretty clear that the company wouldn't jeopardize a broad, disease-modifying label (i.e., inclusion of the Vineland-3 data) for an earlier approval. Our base case still assumes STOK would file on the entirety of the 52-week Ph3 (as described in the updated timeline above), but a more expedited scenario would be an upside driver to the stock in our view. We spoke with mgmt for additional details and provide additional color below.