SPHDF Stock Chart & Stats
$22.28
$0.00(0.00%)
At close: 4:00 PM EST
$22.28
$0.00(0.00%)
Day’s Range― - ―
52-Week Range$11.25 - $24.75
Previous CloseN/A
Volume890.00
Average Volume (3M)37.00
Market Cap
$271.45M
Enterprise Value$302.54M
Total Cash (Recent Filing)$22.44M
Total Debt (Recent Filing)$97.77M
Price to Earnings (P/E)―
Beta-0.46
Next Earnings
Sep 21, 2026EPS Estimate
-0.11Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-3.82
Shares Outstanding15,456,525
10 Day Avg. Volume40
30 Day Avg. Volume37
Financial Highlights & Ratios
PEG Ratio-1.37
Price to Book (P/B)-13.88
Price to Sales (P/S)2.12
P/FCF Ratio-4.71
Enterprise Value/Market Cap1.11
Enterprise Value/Revenue3.92
Enterprise Value/Gross Profit20.91
Enterprise Value/Ebitda-9.87
Forecast
1Y Price Target
$36.74Price Target Upside64.89% Upside
Rating ConsensusModerate Buy
Number of Analyst Covering1
EPS Forecast (FY)-1.51
Revenue Forecast (FY)$119.09M
Bulls Say, Bears Say
Bulls Say
Niche Rare-disease Franchise (AGAMREE)A focused rare-disease product offers durable structural advantages: small, well-defined patient populations, higher per-patient pricing and specialized reimbursement pathways. AGAMREE’s approved status in covered markets creates a stable commercial base and high entry barriers for competitors over the next 2–6 months.
Demonstrated Commercial Traction Via Strong Revenue ReboundA ~57% revenue rebound signals meaningful commercial traction and execution against launches/market access. While profitability remains challenged, sustained top-line growth indicates product-market fit and supports scaled manufacturing, reimbursement expansion, and partner interest over the medium term.
Monetization And Partnering OptionalityThe firm’s ability to out-license rights, secure upfronts, milestones and royalties provides durable strategic flexibility. Partnerships can de-risk launches, accelerate geographic expansion, and supply non-dilutive or milestone-based funding, stabilizing cash needs while leveraging partners' commercial reach.
Bears Say
Negative Equity And Rising DebtNegative shareholders’ equity plus a near-doubling of debt materially weakens the capital structure and reduces financial flexibility. For a small biotech with ongoing burn, this elevates refinancing risk, potential covenant pressure and constrains strategic options over the coming months.
Persistent Operating Cash BurnConsistent negative OCF/FCF (~-35M) indicates the business is not yet self-funding and will likely require external financing or deal-based cash. This structural cash deficit increases dilution or debt reliance and limits ability to sustain launches, marketing and clinical investment without partners.
Volatile Profitability With Recent Deep LossesHigh earnings volatility—positive in 2023 then deep losses in 2024–2025—reduces visibility on sustainable margins and undermines planning. Until margins stabilize, the company faces structural uncertainty about converting revenue growth into durable profitability and cash generation.
SPHDF FAQ
What was Santhera Pharmaceuticals Holding’s price range in the past 12 months?
Santhera Pharmaceuticals Holding lowest stock price was $11.25 and its highest was $24.75 in the past 12 months.
What is Santhera Pharmaceuticals Holding’s market cap?
Santhera Pharmaceuticals Holding’s market cap is $271.45M.
When is Santhera Pharmaceuticals Holding’s upcoming earnings report date?
Santhera Pharmaceuticals Holding’s upcoming earnings report date is Sep 21, 2026 which is in 56 days.
How were Santhera Pharmaceuticals Holding’s earnings last quarter?
Santhera Pharmaceuticals Holding released its earnings results on Apr 28, 2026. The company reported -$0.531 earnings per share for the quarter, the consensus estimate of -$0.531 by $0.
Is Santhera Pharmaceuticals Holding overvalued?
According to Wall Street analysts Santhera Pharmaceuticals Holding’s price is currently Undervalued.
Does Santhera Pharmaceuticals Holding pay dividends?
Santhera Pharmaceuticals Holding does not currently pay dividends.
What is Santhera Pharmaceuticals Holding’s EPS estimate?
Santhera Pharmaceuticals Holding’s EPS estimate is -0.11.
How many shares outstanding does Santhera Pharmaceuticals Holding have?
Santhera Pharmaceuticals Holding has 15,456,525 shares outstanding.
What happened to Santhera Pharmaceuticals Holding’s price movement after its last earnings report?
Santhera Pharmaceuticals Holding reported an EPS of -$0.531 in its last earnings report, expectations of -$0.531. Following the earnings report the stock price went up 1.751%.
Which hedge fund is a major shareholder of Santhera Pharmaceuticals Holding?
Currently, no hedge funds are holding shares in SPHDF
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Company Description
Santhera Pharmaceuticals Holding
Santhera Pharmaceuticals Holding AG, a specialty pharmaceutical company, together with its subsidiaries, develops and sells medicines for rare neuromuscular and pulmonary diseases with high unmet medical need in the Europe, North America, and Asia. The company’s lead pipeline candidate includes Vamorolone, which is developed for the treatments of Duchenne muscular dystrophy. Its clinical stage pipeline also comprises Lonodelestat for the treatment of cystic fibrosis and other neutrophilic pulmonary diseases. Santhera Pharmaceuticals Holding AG was founded in 2004 and is based in Pratteln, Switzerland.
SPHDF Company Deck
SPHDF Earnings Call
Q4 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The earnings call presented a positive outlook with significant market adoption of AGAMREE in Europe and the U.S., strong commercial rollout in China, and increased revenue guidance. However, challenges such as a considerable operating loss and the need for additional financing were also highlighted.View all SPHDF earnings summariesSPHDF Stock 12 Month Forecast
All Analysts
Top Analysts
Average Price Target
$36.74
▲(64.89% Upside)
Technical Analysis
1 Day
3 Days
1 Week
1 Month
Molecular Partners AG
―
Basilea Pharmaceutica
―
Idorsia Ltd
―
Newron Pharmaceuticals SpA
―
Xlife Sciences Ltd.
―
Ownership Overview
―
Insiders
0.08% Mutual Funds
― Other Institutional Investors
99.47% Public Companies and
Individual Investors








