Clinical EfficacyPhase 1 results show deep responses with frequent MRD-negativity and durable complete remissions, suggesting potential survival upside versus current relapsed/refractory AML options.
Regulatory And Scientific MomentumRMAT designation combined with a scheduled oral presentation at ASH and planned additional data disclosures enhances regulatory engagement and visibility that can support development progress.
Safety ProfileSENTI-202 exhibits a favorable tolerability profile with no dose-limiting toxicities, generally mild immune-related events, and rapid hematopoietic recovery, which could widen patient eligibility beyond intensive chemotherapy candidates.