Clinical TrialsSenti’s lead clinical candidate, SENTI-202, is an elegantly designed allogeneic, or off-the-shelf, CAR-NK cell therapy in Ph 1 for relapsed or refractory acute myeloid leukemia—a notoriously treatment-refractory malignancy.
Safety ProfileSENTI-202 has been well tolerated with no dose-limiting toxicities (DLTs) or severe treatment-related adverse events (TEAEs).
Therapeutic InnovationsSenti’s novel Logic-Gated gene circuit platform offers a promising solution to solve the therapeutic window problem that has plagued cell therapies pursuing cancers with 'dirty' antigen targets.