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Silence Therapeutics (SLN)
NASDAQ:SLN
Sln360
Cardiovascular Diseases, Atherosclerosis, Lipoprotein(A)
Phase II
Completed
Evaluate SLN360 in Participants With Elevated Lipoprotein(a) at High Risk of Atherosclerotic Cardiovascular Disease Events
Sep 06, 2022
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Sln124
Polycythemia Vera
Phase I/II
Recruiting
Study to Assess SLN124 in Patients With Polycythemia Vera
Jul 29, 2022
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Sln124
Non-Transfusion-Dependent Thalassemia, Low Risk Myelodysplastic Syndrome, Very-Low Risk Myelodysplastic Syndrome
Phase I
Completed
A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome
Jan 19, 2021
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Sln360
Elevated Lp(A), Dyslipidemias, Hyperlipidemias
Phase I
Completed
Study to Investigate Safety, Tolerability, PK and PD Response of SLN360 in Subjects With Elevated Lipoprotein(a)
Oct 07, 2020
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Sln124
Healthy Volunteers
Early Phase I
Completed
A Phase 1 Study to Evaluate the Safety, Tolerability, PK and PD of SLN124 in Healthy Volunteers
Sep 08, 2020
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Silence Therapeutics (SLN) have in its pipeline
SLN is currently developing the following drugs: Sln360, Sln124, Sln124. These drug candidates are in various stages of clinical development as the company works toward FDA approval.