Strong Revenue Growth
Full-year net sales more than doubled to SEK 71.1 million, representing a 125% increase versus 2024; fourth-quarter net sales rose to SEK 18.6 million, an 88% increase year-over-year.
Very High Gross Margin
Gross profit for the year was SEK 68.7 million, corresponding to a gross margin of 97%, demonstrating high scalability and product-level profitability.
Improved Operating Efficiency
Operating expenses decreased by 16% in the quarter and 7% for the full year; R&D expenses decreased from SEK 121.2 million to SEK 103.0 million (~15% reduction) and G&A decreased to SEK 57.4 million from SEK 60.8 million (~5.6% reduction).
Reduced Loss (Improved EBIT)
EBIT improved to a loss of SEK 224.7 million for the year from SEK 283.0 million the prior year (an improvement of SEK ~58.3 million, ≈20.6% reduction in loss).
Capital Raise to Support Strategy
Rights issue announced up to SEK 200 million, of which SEK 190 million is guaranteed through underwriting and subscription commitments; major shareholder HealthCap and management/board intend to participate.
Commercial Momentum and Market Access Progress
Established commercial organizations in Italy, Spain and Germany; Italy exceeded launch expectations in 2025 and the company reports more than 600 patients treated since EMA approval; market exclusivity extends until 2037 with an estimated SEK 1.5 billion European market potential.
Promising Pipeline Progress — Glioblastoma Opportunity
Preclinical data (GLIOPEP project) for PDCs, particularly OPD5, show near-100% brain bioavailability in animal models, blood-brain barrier penetration, and strong tumor reduction; dual mechanism (nuclear + mitochondrial DNA damage) provides a scientific rationale to address resistant tumors. Plan to initiate a cost-efficient window-of-opportunity (Phase 0) study in ~10 glioblastoma patients in 2026 to confirm BBB passage in humans.
Focused R&D and Externalization Strategy
No ongoing clinical studies but a more focused R&D structure and a shift to rely more on external strategic collaborations to advance preclinical platforms, enabling reallocation of resources to highest-value opportunities.