tiprankstipranks
Trending News
More News >
Roivant Sciences (ROIV)
NASDAQ:ROIV

Roivant Sciences (ROIV) AI Stock Analysis

Compare
710 Followers

Top Page

ROIV

Roivant Sciences

(NASDAQ:ROIV)

Select Model
Select Model
Select Model
Neutral 69 (OpenAI - 5.2)
Rating:69Neutral
Price Target:
$30.00
▲(7.91% Upside)
Action:ReiteratedDate:03/04/26
ROIV scores as moderately attractive, led by strong pipeline/catalyst momentum (earnings call) and significant positive corporate events (Moderna settlement and FDA Priority Review), supported by favorable technical trend. The main constraint is weak financial performance driven by persistent losses and cash burn, with limited valuation support given the negative P/E and no dividend yield provided.
Positive Factors
Strong Cash Runway
A $4.5B consolidated cash balance materially lengthens runway for clinical development and near-term commercial activities, reducing immediate financing pressure. This supports multiple pivotal trials, potential launches and strategic optionality (M&A, buybacks, milestone funding) over the next 2–3 years.
Major Patent Settlement
A large, mostly-cash patent settlement delivers non-dilutive capital and removes a material legal overhang. It also validates Genevant’s LNP IP, strengthening the company’s technology credibility and freeing management to deploy proceeds toward trials, commercialization and shareholder-return programs.
Regulatory Progress for Brepocitinib
Priority Review and an accepted NDA for dermatomyositis shorten regulatory timelines and raise the likelihood of a near-term U.S. launch. If approved, brepocitinib becomes a first-in-class targeted therapy in a high-unmet-need orphan indication, creating a durable commercial foothold across related indications.
Negative Factors
Negative Cash Generation
Persistent negative operating and free cash flow means the business cannot self-fund development from operations. Even with current cash, continued burn elevates reliance on settlements, partnerships or capital markets, increasing execution and dilution risk if clinical timelines slip or commercial launches are delayed.
Volatile, Contracting Revenue
Material revenue contraction and recurring operating losses indicate weak near-term commercial traction and an unstable revenue base. Even with high gross margins, negative net margins and uneven top-line trends undermine sustainable internal funding and heighten dependence on one-time events or partner cashflows.
Clinical Execution Risk
Key Phase II results derive from very small cohorts with baseline imbalances, so effect sizes may not hold in larger, global Phase III trials. This elevates regulatory and execution risk: failed replication could delay approvals, reduce commercial prospects and necessitate additional costly trials.

Roivant Sciences (ROIV) vs. SPDR S&P 500 ETF (SPY)

Roivant Sciences Business Overview & Revenue Model

Company DescriptionRoivant Sciences Ltd., a biopharmaceutical and healthcare technology company that researches and develops medicines. The company develops product candidates for the treatment of various therapeutics, including solid tumors, sickle cell diseases, hypophosphatasia, oncologic malignancies, psoriasis, atopic dermatitis, vitiligo, hyperhidrosis, acne, myasthenia gravis, warm autoimmune hemolytic anemia, thyroid eye diseases, sarcoidosis, and staph aureus bacteremia. The company was founded in 2014 and is based in London, the United Kingdom.
How the Company Makes MoneyRoivant Sciences generates revenue primarily through the development and commercialization of pharmaceutical products. The company makes money from several key revenue streams, including milestone payments from collaborations with pharmaceutical companies, royalties on product sales from its subsidiaries, and potential revenues from licensing agreements. Roivant often partners with larger pharmaceutical companies to co-develop drugs, which can provide upfront payments and shared profits. Additionally, the company may receive funding from investors and venture capitalists to support its research and development activities, further contributing to its financial resources.

Roivant Sciences Earnings Call Summary

Earnings Call Date:Feb 06, 2026
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Jul 01, 2026
Earnings Call Sentiment Positive
The call presented a highly positive clinical development narrative — most notably a strong Phase II win for brepocitinib in cutaneous sarcoidosis with large effect sizes, supportive PROs and clean safety — together with multiple fully enrolled studies and a strong cash position. Key risks discussed include the small size and baseline imbalances of the CS trial (requiring Phase III confirmation), ongoing litigation (Moderna jury trial), high operating expenses and uncertainties around regulatory timelines, pricing and competition. On balance, the breadth of positive clinical results, enrollment momentum, and financial runway outweigh the execution and regulatory/legal risks.
Q3-2025 Updates
Positive Updates
Strong Phase II efficacy in cutaneous sarcoidosis (brepocitinib)
Proof-of-concept, randomized (3:2:2) 16-week study (n=31) showed robust efficacy for brepocitinib 45 mg vs placebo with a placebo-adjusted CSAMI improvement of ~21.6 points (statistically significant). Key outcomes: 100% of patients on brepo 45 mg achieved ≥10-point CSAMI improvement (MCID = 5 points), 62% achieved CSAMI <5 (functional remission), separation from placebo observed as early as Week 4 and maintained through Week 16, consistent improvements on multiple PROs (Skindex-16, KSQ skin domain, patient global impression) and safety with no SAEs and only mild/moderate AEs.
Pipeline and regulatory progress for brepocitinib
Multiple registrational programs in motion: NDA submitted for dermatomyositis, active pivotal programs in NIU and dermatomyositis, Phase III planned to start this year for cutaneous sarcoidosis, and management cites 9+ pivotal readouts expected across programs — positioning brepocitinib as a multi-indication asset across high-unmet-need orphan inflammatory diseases.
Clinical enrollment momentum across portfolio
Several trials are fully enrolled or upsized: IMVT‑1402 DTRA study enrolled 170 patients (upsized from 120, +41.7%), D2T RA and the PH‑ILD (mosli/mostly) studies are fully enrolled — accelerating the timeline for multiple readouts expected later in 2026 and 2027.
Favorable safety profile supported by broader database
Cutaneous sarcoidosis study reported no SAEs and only mild/moderate AEs; company references an overall brepocitinib safety database of >1,500 patients supporting a potentially favorable benefit–risk profile for the indications pursued.
Strong cash position and runway
Consolidated cash of $4.5 billion provides substantial capital to fund ongoing and planned clinical programs and near-term commercial activities; company retains share buyback authorization.
Legal procedural win ahead of trial
Favorable summary judgment ruling on Section 1498 in the Moderna litigation was obtained ahead of the March 9 jury trial, improving aspects of Roivant's asserted case coverage for the litigation.
Negative Updates
Small Phase II sample size and baseline imbalances
Cutaneous sarcoidosis POC study included only 31 patients across 15 sites. Management noted baseline imbalances (longer disease duration and more plaque‑predominant, treatment‑resistant morphology in the 45 mg arm versus 15 mg and placebo) that complicate cross‑arm comparisons and increase reliance on replication in larger Phase III trials.
Risk of effect erosion in larger/global trials
Study was not powered for efficacy and had a very low placebo response; management acknowledged the possibility that placebo behavior or effect sizes could change in larger, global Phase III trials, introducing execution and regulatory risk despite the large effect observed in this small trial.
High operating expenses and continued GAAP losses
Reported R&D expense of $165 million (adjusted non‑GAAP $147 million) and G&A of $175 million (adjusted non‑GAAP $71 million). Total non‑GAAP net loss was $167 million for the quarter. Adjustments reduce R&D by ~10.9% to non‑GAAP and G&A by ~59.4% to non‑GAAP, but cash burn and near‑term losses remain material.
Ongoing litigation and legal uncertainties
Moderna jury trial scheduled to start March 9; multiple Daubert motions pending and outcomes uncertain. While a favorable Section 1498 ruling is positive, litigation represents a material binary risk that could affect business or finances.
Commercial and competitive uncertainties
Price and commercial positioning for brepocitinib are not yet decided (management referenced a pricing envelope between IVIG and Vyvgart as illustrative). Competitive threats and strategic complexities exist (e.g., potential Argenx moves in adjacent indications, sotatercept relevance for PH‑ILD, and Pfizer’s 25% JV ownership requiring below‑the‑line minority interest accounting), all adding commercialization uncertainty.
Company Guidance
Management laid out a catalyst‑rich 2026: brepocitinib already has an NDA in dermatomyositis and a Phase III in cutaneous sarcoidosis will start this year after a 31‑patient Phase II that showed a placebo‑adjusted CSAMI delta of ~21.6 points (statistically significant), 100% of 45 mg patients achieved ≥10‑point improvement, 62% reached CSAMI <5, with separation vs placebo as early as Week 4 and no SAEs (all AEs mild/moderate); a pivotal NIU Phase III readout is expected in H2 2026; Phase IIb mosli (PH‑ILD) and IMVT‑1402 D2T RA studies are fully enrolled (IMVT‑1402 DTRA enrolled 170 v. planned 120) with data expected in H2 2026, POC reads in 1402 and CLE are planned this year, and the Moderna jury trial begins March 9; financials for the quarter were R&D $165M (adj. $147M), G&A $175M (adj. $71M), non‑GAAP net loss $167M and $4.5B cash, and management reiterated 9+ pivotal readouts and multiple potential commercial launches over the coming years.

Roivant Sciences Financial Statement Overview

Summary
Financials are mixed and skew weak: volatile/contracting revenue (~35% TTM decline) and deeply negative profitability with substantial operating losses. Cash flow is consistently negative (ongoing cash burn), partially offset by a strong, low-leverage balance sheet (debt-to-equity ~2%) that provides runway.
Income Statement
28
Negative
Revenue has been volatile and is contracting, with TTM (Trailing-Twelve-Months) revenue down ~35% and multiple years of uneven growth. Despite very strong gross margins (mid‑90% range in recent periods), profitability is weak: TTM net margin is deeply negative and operating losses remain substantial. The 2024 annual period shows an outsized net profit that looks non-recurring versus the surrounding loss-making years, which reduces confidence in earnings consistency.
Balance Sheet
78
Positive
The balance sheet is a relative strength. Leverage is low, with debt-to-equity around ~2% in the latest annual and TTM (Trailing-Twelve-Months) periods, and equity is sizeable versus total assets. While returns on equity are negative in most periods (reflecting ongoing losses), the company appears well-capitalized with limited balance-sheet debt risk.
Cash Flow
32
Negative
Cash generation is weak, with operating cash flow and free cash flow consistently negative across all shown periods, indicating ongoing cash burn. Free cash flow deterioration in TTM (Trailing-Twelve-Months) (down ~2% vs the prior period) adds pressure, and cash outflows are not yet stabilizing. While cash burn tracks reported losses in direction, the business has not demonstrated sustainable cash self-funding.
BreakdownTTMMar 2025Mar 2024Mar 2023Mar 2022Mar 2021
Income Statement
Total Revenue13.31M29.05M32.71M61.28M55.29M23.80M
Gross Profit12.14M28.14M31.11M48.15M46.32M21.74M
EBITDA-1.02B-1.10B-802.89M-1.18B-910.77M-720.58M
Net Income-809.24M-171.98M4.35B-1.01B-845.26M-809.23M
Balance Sheet
Total Assets5.23B5.44B7.22B2.39B2.59B2.69B
Cash, Cash Equivalents and Short-Term Investments4.53B4.89B6.54B1.68B2.06B2.13B
Total Debt207.44M100.17M499.75M481.40M283.89M244.98M
Total Liabilities251.14M249.74M773.95M782.02M523.70M527.69M
Stockholders Equity4.27B4.69B5.97B1.16B1.66B1.90B
Cash Flow
Free Cash Flow-766.86M-844.05M-766.65M-856.08M-695.16M-557.94M
Operating Cash Flow-759.10M-839.45M-765.27M-843.39M-677.73M-552.14M
Investing Cash Flow257.62M-1.77B5.20B-44.27M303.30M-31.70M
Financing Cash Flow-13.39M-1.22B419.36M499.46M306.79M456.26M

Roivant Sciences Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price27.80
Price Trends
50DMA
25.56
Positive
100DMA
23.18
Positive
200DMA
18.01
Positive
Market Momentum
MACD
0.77
Positive
RSI
51.53
Neutral
STOCH
12.10
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ROIV, the sentiment is Neutral. The current price of 27.8 is below the 20-day moving average (MA) of 28.53, above the 50-day MA of 25.56, and above the 200-day MA of 18.01, indicating a neutral trend. The MACD of 0.77 indicates Positive momentum. The RSI at 51.53 is Neutral, neither overbought nor oversold. The STOCH value of 12.10 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for ROIV.

Roivant Sciences Risk Analysis

Roivant Sciences disclosed 98 risk factors in its most recent earnings report. Roivant Sciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Roivant Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
$7.51B25.4592.67%31.19%59.01%
69
Neutral
$19.90B-14.22-18.32%-83.82%-109.22%
69
Neutral
$11.11B12.74-8.82%4.14%-179.96%
67
Neutral
$3.54B36.2715.25%17.92%-26.13%
65
Neutral
$7.95B60.284.10%0.54%3.85%-48.17%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ROIV
Roivant Sciences
27.80
16.83
153.42%
CORT
Corcept Therapeutics
33.30
-24.29
-42.18%
HALO
Halozyme
63.65
-0.67
-1.04%
JAZZ
Jazz Pharmaceuticals
180.45
39.88
28.37%
TECH
Bio-Techne
50.81
-9.18
-15.30%

Roivant Sciences Corporate Events

Business Operations and StrategyStock BuybackLegal Proceedings
Roivant Subsidiary Reaches Major Global Patent Settlement
Positive
Mar 3, 2026

On March 3, 2026, Roivant’s subsidiary Genevant Sciences and partner Arbutus Biopharma reached a $2.25 billion global settlement with Moderna to resolve all U.S. and international patent litigation over Moderna’s use of their lipid nanoparticle delivery technology in COVID-19 vaccines, including Spikevax. The deal includes a $950 million upfront payment due by July 8, 2026, a further contingent payment of up to $1.3 billion linked to the outcome of Moderna’s appeal on Section 1498, and Moderna’s consent to judgments of infringement and no invalidity on four patents.

As part of the settlement, Genevant and Arbutus will grant Moderna a fully paid-up, royalty-free, irrevocable global non-exclusive license and covenant not to sue covering SM-102-based LNP formulations in certain mRNA infectious-disease vaccines, ending all related patent disputes between the parties. Roivant highlighted that, if fully realized, this would be one of the largest patent settlements in the pharmaceutical sector, bolsters the credibility of its LNP intellectual property amid ongoing Pfizer/BioNTech litigation, and supports capital allocation moves such as a $1 billion share repurchase program approved by its board.

The most recent analyst rating on (ROIV) stock is a Buy with a $31.00 price target. To see the full list of analyst forecasts on Roivant Sciences stock, see the ROIV Stock Forecast page.

Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Roivant’s Priovant Unit Gains FDA Priority Review for Brepocitinib
Positive
Mar 3, 2026

On March 3, 2026, Roivant subsidiary Priovant Therapeutics said the U.S. Food and Drug Administration accepted its New Drug Application for brepocitinib to treat dermatomyositis and granted the filing Priority Review. The FDA set a Prescription Drug User Fee Act target action date in the third quarter of 2026, positioning brepocitinib for a potential U.S. launch at the end of September 2026 if approved.

The Priority Review is backed by positive Phase 3 VALOR trial data, the largest and longest interventional dermatomyositis study, in which brepocitinib 30 mg showed statistically significant and clinically meaningful benefits across primary and key secondary endpoints versus placebo. If approved, brepocitinib would become the first targeted therapy for dermatomyositis, potentially reshaping care for patients reliant on chronic high-dose steroids and enhancing Roivant’s presence in autoimmune therapeutics.

Priovant reported that serious infections were more frequent with brepocitinib 30 mg than placebo but were generally manageable, while malignancies, cardiovascular and thromboembolic events occurred more often in the placebo arm, supporting a safety profile comparable to existing JAK and TYK2 inhibitors. The breadth of the VALOR safety database and inclusion of patients with significant comorbidities may bolster regulatory confidence and strengthen the drug’s commercial case in a high unmet-need market.

The most recent analyst rating on (ROIV) stock is a Hold with a $31.00 price target. To see the full list of analyst forecasts on Roivant Sciences stock, see the ROIV Stock Forecast page.

Business Operations and StrategyPrivate Placements and FinancingProduct-Related Announcements
Roivant Sciences Highlights Pipeline Progress at Investor Day
Positive
Dec 11, 2025

On December 11, 2025, Roivant Sciences hosted its Investor Day, highlighting significant progress in its pipeline and outlining its growth strategy. The company announced plans for multiple product launches and filings over the next three years, including brepocitinib for dermatomyositis, with a commercial launch expected in early 2027. Roivant also reported positive updates on clinical trials, including accelerated timelines for brepocitinib in non-infectious uveitis and cutaneous sarcoidosis, as well as the IMVT-1402 trial for rheumatoid arthritis. Additionally, Roivant’s financing efforts have extended Immunovant’s cash runway to support the launch of IMVT-1402 in Graves’ disease, positioning the company for long-term shareholder value creation.

The most recent analyst rating on (ROIV) stock is a Hold with a $22.50 price target. To see the full list of analyst forecasts on Roivant Sciences stock, see the ROIV Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 04, 2026