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TransCode Therapeutics (RNAZ)
NASDAQ:RNAZ
US Market

TransCode Therapeutics (RNAZ) AI Stock Analysis

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TransCode Therapeutics

(NASDAQ:RNAZ)

24Underperform
TransCode Therapeutics exhibits significant financial challenges with no revenue and high expenses typical of an early-stage biotech. The technical analysis suggests an oversold condition, but the bearish trend remains strong. Valuation metrics are unfavorable, highlighting the speculative and high-risk nature of the investment.
Positive Factors
Clinical Development
The safety review committee has approved opening of Cohort 4 in the Phase 1 trial evaluating TTX-MC138 in advanced/metastatic solid tumors, based on favorable safety observed in previous cohorts.
Financial Resources
TransCode ended 2024 with $5.8M in cash and equivalents, which does not include the recent $8.8M equity raise, assumed sufficient to fund operations into 2026.
Strategic Partnerships
The company is engaged in potential pipeline partnerships, indicating strategic growth opportunities following the presentation of initial data.
Negative Factors
Clinical Risks
Risks include safety signals emerging with any of the company’s clinical or preclinical programs and efficacy from clinical programs being lower than expected.
Investor Sentiment
Investors may be disappointed with not seeing initial responses.
Operating Expenses
In 4Q24, the company reported operating expenses of $5.1M, which was significantly higher than 3Q24, likely associated with costs related to dose escalation in the Phase 1 trial of TTX-MC138 for treatment of solid tumors.

TransCode Therapeutics (RNAZ) vs. S&P 500 (SPY)

TransCode Therapeutics Business Overview & Revenue Model

Company DescriptionTransCode Therapeutics, Inc., a biopharmaceutical company, engages in the development and commercialization of drugs and diagnostics for treating and identifying metastatic disease. Its lead therapeutic candidate, TTX-MC138, is a preclinical stage product for the treatment of metastatic cancer. The company's products in preclinical programs include TTX-siPDL1, an siRNA-based modulator of programmed death-ligand 1; TTX-siLIN28B, an siRNA-based inhibitor of RNA-binding protein LIN28B. Its cancer agnostic programs comprise TTX-RIGA, an RNA–based agonist of the RIG-I-driven immune response in the tumor microenvironment; TTX-CRISPR, a CRISPR/Cas9–based therapy platform for the repair or elimination of cancer-causing genes inside tumor cells; and TTX-mRNA, an mRNA-based platform for the development of cancer vaccines meant to activate cytotoxic immune responses against tumor cells. The company was incorporated in 2016 and is based in Boston, Massachusetts.
How the Company Makes MoneyTransCode Therapeutics primarily generates revenue through the development and potential commercialization of its RNA-based therapeutic candidates. The company may enter into collaborative agreements or partnerships with larger pharmaceutical companies to co-develop or license its technologies, which can result in upfront payments, milestone payments, and royalties on sales. Additionally, TransCode might receive funding through grants or research collaborations that support their R&D activities. As a biotechnology firm, the company's earnings are heavily reliant on the successful clinical development and eventual market approval of its drug candidates.

TransCode Therapeutics Financial Statement Overview

Summary
TransCode Therapeutics faces significant financial challenges, characterized by limited revenue generation and persistent losses. The balance sheet shows minimal leverage, but declining equity ratios suggest weakening financial stability. Cash flow statements highlight liquidity concerns, with negative cash flows influencing the company's ability to sustain operations without additional financing.
Income Statement
15
Very Negative
TransCode Therapeutics has shown minimal revenue generation in the TTM (Trailing-Twelve-Months) period with negative profit margins. The gross profit margin is 43.6%, but the company is struggling to cover its operational costs, as indicated by significant negative EBIT and net profit margins. Revenue growth is not applicable due to negligible prior revenue.
Balance Sheet
30
Negative
The company maintains a low debt-to-equity ratio of 0.09, which suggests limited reliance on debt financing. However, the equity ratio has fallen to 42% in the TTM, indicating a decreasing proportion of equity financing. The company's negative net income results in a negative ROE, reflecting challenges in generating returns for shareholders.
Cash Flow
20
Very Negative
TransCode Therapeutics exhibits negative free cash flow and operating cash flow. The cash flow metrics indicate that the company is not generating sufficient cash from operations to cover investment and financing activities, posing a risk to liquidity and ongoing operations.
Breakdown
Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019
Income StatementTotal Revenue
0.000.000.000.000.00
Gross Profit
-516.75K-98.61K-42.47K0.000.00
EBIT
-19.42M-18.67M-6.15M-726.60K-456.87K
EBITDA
-17.97M-17.47M-6.11M0.000.00
Net Income Common Stockholders
-18.55M-35.13M-6.94M-2.74M-764.14K
Balance SheetCash, Cash Equivalents and Short-Term Investments
2.77M4.97M20.83M828.02K204.47K
Total Assets
5.17M7.59M22.94M1.06M204.47K
Total Debt
450.57K0.000.002.09M927.81K
Net Debt
-2.32M-4.97M-20.83M1.26M723.34K
Total Liabilities
3.53M4.35M2.53M4.46M1.31M
Stockholders Equity
1.64M3.24M20.40M-3.41M-1.11M
Cash FlowFree Cash Flow
-18.11M-15.86M-5.52M-492.97K-508.51K
Operating Cash Flow
-18.07M-15.76M-5.27M-492.97K-508.51K
Investing Cash Flow
-35.61K-100.92K-251.82K0.000.00
Financing Cash Flow
15.91M5.99K25.52M1.12M500.00K

TransCode Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.41
Price Trends
50DMA
1.53
Negative
100DMA
3.94
Negative
200DMA
8.99
Negative
Market Momentum
MACD
-0.32
Negative
RSI
33.76
Neutral
STOCH
71.53
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RNAZ, the sentiment is Neutral. The current price of 0.41 is above the 20-day moving average (MA) of 0.39, below the 50-day MA of 1.53, and below the 200-day MA of 8.99, indicating a neutral trend. The MACD of -0.32 indicates Negative momentum. The RSI at 33.76 is Neutral, neither overbought nor oversold. The STOCH value of 71.53 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for RNAZ.

TransCode Therapeutics Risk Analysis

TransCode Therapeutics disclosed 91 risk factors in its most recent earnings report. TransCode Therapeutics reported the most risks in the “Finance & Corporate” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

TransCode Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$5.38B3.59-41.63%2.87%17.72%1.87%
PTPTN
40
Underperform
$5.63M422.38%-95.07%40.41%
38
Underperform
$7.54M-310.98%50.90%42.10%
34
Underperform
$8.56M
-73095.97%
33
Underperform
$15.92M-224.18%-75.88%
24
Underperform
$9.49M-490.03%99.64%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RNAZ
TransCode Therapeutics
0.41
-22.92
-98.24%
PTN
Palatin Technologies
0.22
-1.83
-89.27%
EVGN
Evogene
1.13
-5.93
-83.99%
MTVA
MetaVia
0.76
-2.97
-79.62%
SLXN
Silexion Therapeutics
0.98
-99.46
-99.02%
LIPO
Lipella Pharmaceuticals, Inc.
2.49
-3.51
-58.50%

TransCode Therapeutics Corporate Events

Private Placements and FinancingRegulatory Filings and Compliance
TransCode Therapeutics Raises $8M in Private Placement
Positive
Dec 2, 2024

TransCode Therapeutics, Inc. recently executed a private placement agreement with institutional investors, raising approximately $8 million to bolster working capital and corporate initiatives. The deal includes issuing shares, Series C, and Series D warrants, subject to stockholder approval, and aims to bring the company into compliance with Nasdaq’s equity requirements. This strategic move reflects TransCode’s commitment to advancing its RNA therapeutic platform in oncology, while navigating regulatory frameworks to ensure continued Nasdaq listing.

Delistings and Listing ChangesStock Split
TransCode Therapeutics Announces Reverse Stock Split
Neutral
Nov 29, 2024

TransCode Therapeutics has announced a 1-for-33 reverse stock split aimed at boosting its stock price to meet Nasdaq’s minimum bid requirements. This split, effective December 4, 2024, will consolidate every 33 shares into one, streamlining the number of shares from over 17 million to approximately 523,202. The move, expected to affect all shareholders equally, comes as part of TransCode’s strategy to maintain its Nasdaq listing, with no fractional shares being issued as shares will be rounded up.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.