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Prothena (PRTA)
NASDAQ:PRTA
PRTA Stock Chart & Stats
$10.00
<$0.01(0.07%)
At close: 4:00 PM EST
$10.00
<$0.01(0.07%)
Day’s Range― - ―
52-Week Range$4.32 - $16.67
Previous CloseN/A
Volume58.73K
Average Volume (3M)732.47K
Market Cap
$538.30M
Enterprise Value$216.54M
Total Cash (Recent Filing)$330.84M
Total Debt (Recent Filing)$9.08M
Price to Earnings (P/E)―
Beta0.99
Next Earnings
Feb 12, 2026EPS Estimate
-0.56Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-0.68
Shares Outstanding53,829,983
10 Day Avg. Volume686,318
30 Day Avg. Volume732,465
Financial Highlights & Ratios
PEG Ratio0.34
Price to Book (P/B)1.53
Price to Sales (P/S)5.51
P/FCF Ratio-4.95
Enterprise Value/Market Cap0.40
Enterprise Value/Revenue18.37
Enterprise Value/Gross Profit-12.62
Enterprise Value/Ebitda-0.99
Forecast
1Y Price Target
$20.33Price Target Upside103.30% Upside
Rating ConsensusModerate Buy
Number of Analyst Covering6
EPS Forecast (FY)N/A
Revenue Forecast (FY)N/A
Bulls Say, Bears Say
Bulls Say
Biomarker Evidence And Clinical DifferentiationCoramitug's Phase 2 biomarker profile showed a large and rapid NT-proBNP reduction, supporting its amyloid-clearing mechanism and suggesting potential for superior clinical outcomes versus existing stabilizers and silencers.
Partnerships And FundingPartnerships with Novo Nordisk and Roche advancing into Phase 3 shift development costs to partners while preserving milestone and royalty upside, creating asymmetric value potential that may not be reflected in the current valuation.
Platform TechnologyCYTOPE technology demonstrated systemic, non-lytic intracellular delivery that crossed the blood-brain barrier and reduced pathogenic TDP-43 in models, positioning the company to target previously undruggable intracellular proteins and attract strategic collaborations.
Bears Say
Analyst SentimentA reiterated Underperform rating reflects continued sell-side skepticism that could weigh on investor perception and put downward pressure on the stock.
Clinical Efficacy RiskPrasinezumab's prior failure to show a statistically significant benefit in early Parkinson's, combined with historically low success rates for Phase 3 Parkinson's trials, increases the program's clinical risk and reduces the likelihood of a regulatory win.
Market Competition And PositioningCoramitug would enter an already crowded ATTR treatment market and is likely to be used as a later-line therapy for more severe patients, which could limit commercial uptake and peak sales potential.
Prothena News
PRTA FAQ
What was Prothena’s price range in the past 12 months?
Prothena lowest stock price was $4.32 and its highest was $16.66 in the past 12 months.
What is Prothena’s market cap?
Prothena’s market cap is $538.30M.
When is Prothena’s upcoming earnings report date?
Prothena’s upcoming earnings report date is Feb 12, 2026 which is in 18 days.
How were Prothena’s earnings last quarter?
Prothena released its earnings results on Nov 06, 2025. The company reported -$0.68 earnings per share for the quarter, beating the consensus estimate of -$0.687 by $0.007.
Is Prothena overvalued?
According to Wall Street analysts Prothena’s price is currently Undervalued.
Does Prothena pay dividends?
Prothena does not currently pay dividends.
What is Prothena’s EPS estimate?
Prothena’s EPS estimate is -0.56.
How many shares outstanding does Prothena have?
Prothena has 53,829,983 shares outstanding.
What happened to Prothena’s price movement after its last earnings report?
Prothena reported an EPS of -$0.68 in its last earnings report, beating expectations of -$0.687. Following the earnings report the stock price went up 4.762%.
Which hedge fund is a major shareholder of Prothena?
Currently, no hedge funds are holding shares in PRTA
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Prothena Stock Smart Score
Neutral
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Analyst Consensus
Moderate Buy
Average Price Target:
$20.33 (103.30% Upside)
$20.33 (103.30% Upside)
Hedge Fund Trend
Increased
By 19.4K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Positive
Last 7 Days ▼ 1.6%
Last 30 Days ▲ 4.2%
Last 30 Days ▲ 4.2%
Technicals
SMA
Positive
20 days / 200 days
Momentum
-39.39%
12-Months-Change
Fundamentals
Return on Equity
-67.63%
Trailing 12-Months
Asset Growth
-38.18%
Trailing 12-Months
Company Description
Prothena
Prothena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company is involved in developing Birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, which is in Phase IIb clinical trial for the treatment of Parkinson's disease; PRX004 that completed Phase I clinical trial for the treatment of Transthyretin amyloidosis; and PRX005, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX012 for the treatment of Alzheimer's disease; and dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein; and a collaboration agreement with Bristol-Myers Squibb to develop antibodies. The company was founded in 2012 and is based in Dublin, Ireland.
PRTA Stock 12 Month Forecast
Average Price Target
$20.33
▲(103.30% Upside)
Technical Analysis
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Ownership Overview
24.47% Insiders
19.23% Mutual Funds
0.31% Other Institutional Investors
46.72% Public Companies and
Individual Investors