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Purple Biotech (PPBT)
NASDAQ:PPBT

Purple Biotech (PPBT) AI Stock Analysis

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PPBT

Purple Biotech

(NASDAQ:PPBT)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$0.65
▲(3.65% Upside)
The score is held down primarily by the lack of revenue, ongoing losses, and negative free cash flow, indicating continued reliance on external funding. Technical indicators also point to a bearish trend with weak momentum. The main positive is the low-debt balance sheet, which reduces near-term leverage risk but does not offset weak operating fundamentals.
Positive Factors
Strong Partnerships
Partnerships and collaborations provide a sustainable revenue stream through upfront payments, milestone payments, and potential royalties, enhancing financial stability and growth prospects.
Low Leverage
Low leverage reduces financial risk and enhances the company's ability to navigate economic downturns, providing a stable foundation for future growth.
Clinical Progress
Advancements in clinical milestones and pipeline progress indicate potential for future product launches, which can drive long-term revenue growth and market expansion.
Negative Factors
Consistent Net Losses
Ongoing net losses highlight financial instability, limiting the company's ability to invest in growth opportunities and potentially affecting long-term viability.
Negative Cash Flow
Negative cash flow reflects inefficiencies in cash generation, necessitating reliance on external financing, which could constrain future operational flexibility and growth.
Revenue Challenges
The absence of revenue growth underscores significant operational challenges, limiting the company's ability to achieve profitability and sustain long-term operations.

Purple Biotech (PPBT) vs. SPDR S&P 500 ETF (SPY)

Purple Biotech Business Overview & Revenue Model

Company DescriptionPurple Biotech Ltd., a clinical-stage company, focuses on developing therapies to overcome tumor immune evasion and drug for cancer patients in the United States. Its oncology pipeline includes CM24, a monoclonal antibody that blocks carcinoembryonic antigen related cell adhesion molecule 1 as a combination therapy with anti-PD-1 checkpoint inhibitors, which is in Phase 1b/2 clinical trials for the treatment of non-small cell lung cancer and pancreatic cancer; and NT219, a small molecule that targets insulin receptor substrate 1 and 2, and signal transducer and activator of transcription, which is in Phase 1/2 clinical trials for the treatment of recurrent and/or metastatic solid tumors and squamous cell carcinoma of the head and neck cancer. The company was formerly known as Kitov Pharma Ltd and changed its name to Purple Biotech Ltd. in December 2020. The company is headquartered in Rehovot, Israel.
How the Company Makes MoneyPurple Biotech generates revenue primarily through partnerships and collaborations with other pharmaceutical and biotechnology companies, as well as through licensing agreements. These partnerships may involve co-development and commercialization of their drug candidates, which can provide upfront payments, milestone payments, and potential royalties on sales. Additionally, the company may receive government grants or funding from research institutions to support its clinical trials and drug development initiatives. As Purple Biotech advances through clinical stages, successful trials can lead to increased valuation and potential acquisition offers, further contributing to its financial growth.

Purple Biotech Financial Statement Overview

Summary
Purple Biotech faces severe financial struggles, marked by consistent net losses, zero revenue generation, and negative cash flows. Although the balance sheet indicates low leverage, the ongoing financial distress and lack of revenue generation highlight significant challenges.
Income Statement
12
Very Negative
The income statement for Purple Biotech shows consistent revenue challenges with total revenues recording as zero for the latest periods. Gross profit margins are non-existent due to the absence of revenue, and the company has been operating at a net loss for several years, highlighted by a negative EBIT and EBITDA. Despite a slight reduction in net loss from the previous year, the absence of revenue growth and persistent operating losses suggest significant financial distress.
Balance Sheet
74
Positive
Purple Biotech's balance sheet reflects a relatively stable equity base, with stockholders' equity significantly surpassing total liabilities. The equity ratio remains strong, indicating low leverage, which is a positive aspect. However, the debt-to-equity ratio is minimal due to low debt levels. Despite these strengths, the continuous net losses and shrinking total assets are concerns for long-term sustainability.
Cash Flow
18
Very Negative
The cash flow situation for Purple Biotech is concerning, with consistent negative operating cash flow and free cash flow, indicating ongoing cash burn. Although there is a slight improvement in operating cash flow from the previous year, the free cash flow remains negative, and the company relies heavily on financing activities. The ratio of operating cash flow to net income is unfavorable, highlighting inefficiencies in cash generation relative to reported losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.00195.80K0.000.001.00M
Gross Profit-146.25K-186.00K-196.00-120.00-55.00999.94K
EBITDA-3.55M-7.05M-19.88M-21.49M-17.52M-28.41M
Net Income-3.26M-7.24M-19.88K-21.67M-18.38M-28.00M
Balance Sheet
Total Assets39.06M37.04M44.30M54.62M70.20M83.80M
Cash, Cash Equivalents and Short-Term Investments10.45M8.52M15.41M32.11M47.20M57.80M
Total Debt256.00K183.00K351.00K515.00K749.00K895.00K
Total Liabilities6.25M4.13M10.01M7.52M5.09M4.05M
Stockholders Equity32.77M32.86M34.21M46.91M64.83M79.39M
Cash Flow
Free Cash Flow-5.54M-14.37M-19.93M-16.96M-15.19M-12.25M
Operating Cash Flow-6.54M-14.37M-19.93M-16.73M-15.07M-12.09M
Investing Cash Flow727.13K509.00K13.88M19.91M13.41M-49.59M
Financing Cash Flow10.00M6.77M5.45M1.11M1.51M68.49M

Purple Biotech Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.63
Price Trends
50DMA
0.75
Negative
100DMA
0.77
Negative
200DMA
1.60
Negative
Market Momentum
MACD
-0.03
Positive
RSI
33.27
Neutral
STOCH
18.17
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PPBT, the sentiment is Negative. The current price of 0.63 is below the 20-day moving average (MA) of 0.69, below the 50-day MA of 0.75, and below the 200-day MA of 1.60, indicating a bearish trend. The MACD of -0.03 indicates Positive momentum. The RSI at 33.27 is Neutral, neither overbought nor oversold. The STOCH value of 18.17 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PPBT.

Purple Biotech Risk Analysis

Purple Biotech disclosed 74 risk factors in its most recent earnings report. Purple Biotech reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Purple Biotech Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$6.87M-1.33-145.65%68.59%
44
Neutral
$18.80M-0.1152.39%
43
Neutral
$6.50M-0.62-10.56%88.64%
29
Underperform
$3.96M-0.06-168.95%90.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PPBT
Purple Biotech
0.63
-2.91
-82.12%
TCRT
Alaunos Therapeutics
3.08
1.32
75.00%
OGEN
Oragenics
0.95
-7.51
-88.77%
PMCB
PharmaCyte Biotech
0.89
-0.78
-46.71%
KALA
KALA BIO
0.68
-7.01
-91.21%

Purple Biotech Corporate Events

Purple Biotech Unveils January 2026 Corporate Update, Mapping 2026 Catalysts for CAPTN-3 and Oncology Pipeline
Jan 13, 2026

On January 12, 2026, Purple Biotech released an updated corporate presentation outlining progress on its CAPTN‑3 tri‑specific antibody platform and near‑term milestones for its oncology pipeline. The company highlighted lead candidate IM1240, a capped CD3x5T4xNKG2A antibody for solid tumors that showed a 300‑fold safety margin versus its non‑capped variant in preclinical models and is slated for GLP toxicology completion, IND submission, and Phase 1 initiation in the second half of 2026. The presentation also positioned Phase 2 assets CM24 (pancreatic cancer) and NT219 (head and neck cancer) as partnership opportunities, with interim Phase 2 data for NT219 expected in 2026 and a Phase 2b start for CM24 contingent on partnering, framing 2026 as a catalyst‑rich year that could de‑risk the CAPTN‑3 platform and potentially enhance Purple Biotech’s standing in the competitive immuno‑oncology space.

The most recent analyst rating on (PPBT) stock is a Hold with a $0.66 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Reports Key Toxicology Milestone for CAPTN-3 Antibody IM1240
Jan 7, 2026

On January 7, 2026, Purple Biotech reported that its tri-specific antibody IM1240, from the CAPTN-3 platform, successfully completed a non-human primate toxicology study, showing dosing tolerance up to 300 times higher than a non-capped comparator with markedly reduced immune-related toxicity and minimal cytokine release. The study also demonstrated a favorable pharmacokinetic profile, including increased systemic exposure and prolonged half-life attributed to IM1240’s capping design and albumin moiety, reinforcing the potential for an expanded therapeutic window and supporting its progression toward first-in-human clinical development with further advanced toxicological assessments planned.

The most recent analyst rating on (PPBT) stock is a Hold with a $0.65 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Shareholders Approve Key Proposals at December Meeting
Dec 16, 2025

On December 15, 2025, Purple Biotech Ltd. held an Extraordinary General Meeting of Shareholders at its headquarters in Rehovot, Israel. During the meeting, all proposals outlined in the company’s Proxy Statement were approved by the shareholders, in accordance with Israeli Companies Law and the company’s articles of association. This approval signifies a strategic alignment among stakeholders, potentially impacting the company’s future operations and market positioning.

The most recent analyst rating on (PPBT) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Announces Positive Preclinical Data at ESMO IO Congress 2025
Dec 11, 2025

On December 11, 2025, Purple Biotech reported positive preclinical data from its CAPTN-3 tri-specific antibody platform at the ESMO Immuno-Oncology Congress 2025. The data highlighted significant anti-tumor activity of two antibodies, IM1240 and IM1305, across different tumor antigens, with IM1240 showing effectiveness even in PD1-resistant models. These findings underscore the platform’s potential applicability across a range of solid tumors and support the company’s development roadmap as it prepares for key milestones in 2026.

The most recent analyst rating on (PPBT) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Unveils November 2025 Corporate Presentation Highlighting Oncology Advances
Nov 19, 2025

On November 19, 2025, Purple Biotech Ltd. released an updated corporate presentation highlighting its innovative drug development efforts. The company is uniquely positioned in the oncology field with its CAPTN-3 platform, which combines T-cell and NK cell engagement to enhance cancer treatment efficacy. The presentation underscores the company’s strategic focus on advancing its oncology pipeline, with promising results from Phase 1 and Phase 2 trials, and a cash balance providing financial runway into the first half of 2027.

The most recent analyst rating on (PPBT) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Announces Q3 2025 Financial Results and Advances CAPTN-3 Platform
Nov 14, 2025

On November 14, 2025, Purple Biotech announced its third-quarter financial results and business update. The company highlighted the development of its CAPTN-3 platform, including the initiation of a second tri-specific antibody targeting TROP2 and achieving a manufacturing milestone for IM1240. With a cash position of $10.5 million as of September 30, 2025, Purple Biotech anticipates a cash runway into the first half of 2027, supporting significant milestones. The company plans to conduct toxicology studies and initiate a Phase 1 study for IM1240 in 2026. Financially, Purple Biotech reported a decrease in research and development expenses and operating loss compared to the previous year, primarily due to reduced costs associated with the CM24 Phase 2 study.

The most recent analyst rating on (PPBT) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Reaches Manufacturing Milestone for IM1240 Antibody
Oct 29, 2025

On October 29, 2025, Purple Biotech announced a significant manufacturing milestone for IM1240, a tri-specific antibody from its CAPTN-3 platform. This achievement validates the scalability of their platform and positions IM1240 competitively for future development, advancing it towards first-in-human clinical trials with an IND submission planned for 2026. The milestone demonstrates Purple Biotech’s capability to produce complex antibodies with high yield and purity, potentially offering a safer therapeutic profile by limiting immune activation to the tumor microenvironment.

The most recent analyst rating on (PPBT) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Announces Extraordinary General Meeting for December 2025
Oct 28, 2025

On October 28, 2025, Purple Biotech Ltd. announced an upcoming Extraordinary General Meeting of Shareholders scheduled for December 15, 2025. The meeting aims to approve equity-based awards for the CEO and directors. Shareholders and holders of American Depositary Shares are invited to participate and vote on the proposals. The meeting’s outcome could impact the company’s governance and compensation structure, potentially influencing investor confidence and market perception.

The most recent analyst rating on (PPBT) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Purple Biotech Receives Nasdaq Bid Price Notification
Oct 20, 2025

On October 16, 2025, Purple Biotech received a notification from Nasdaq indicating non-compliance with the minimum bid price requirement, as its American Depositary Shares (ADSs) have been below $1.00 for 30 consecutive trading days. The company has until April 14, 2026, to regain compliance by achieving a closing bid price of $1.00 or more for ten consecutive business days. This notification does not immediately affect the company’s Nasdaq listing or the trading of its ADSs, and the company is considering options to address the deficiency, including adjusting the ratio between its ADSs and ordinary shares.

The most recent analyst rating on (PPBT) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025