Capital And Dilution RiskPotential need for additional equity financing could dilute existing shareholders and slow progress toward analyst price objectives by increasing share count and funding uncertainty.
Commercialization And Competitive RisksValuation approaches embed sizable clinical, commercialization, and reimbursement risk adjustments, reflecting uncertainty about future market uptake relative to competitors and payor acceptance.
Evidence Uncertainty From Small CohortsEfficacy signals are derived from a small patient cohort, creating notable uncertainty that requires confirmation in larger, randomized registration trials before broader confidence in results.