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NRX Pharmaceuticals (NRXP)
NASDAQ:NRXP
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NRX Pharmaceuticals (NRXP) AI Stock Analysis

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NRXP

NRX Pharmaceuticals

(NASDAQ:NRXP)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
NRX Pharmaceuticals is navigating significant financial hurdles with net losses and negative equity, typical for early-stage biotech firms. However, strategic initiatives and drug development progress provide potential upside. Technical analysis and valuation reflect speculative potential, with the stock currently exhibiting mixed technical signals. The positive outlook from the earnings call highlights strategic moves that could improve the company's financial health if successful.
Positive Factors
FDA Fast Track Designation
The FDA Fast Track designation for NRX-100 indicates strong potential to address unmet medical needs, accelerating development and review processes, which could lead to earlier commercialization and revenue generation.
Strategic Partnerships
The strategic partnership for NRX-100 validates the company's drug development approach and provides a significant financial opportunity through milestone payments and royalties, enhancing long-term revenue prospects.
HOPE Therapeutics Expansion
Expanding HOPE Therapeutics with profitable clinics positions the company to increase its market presence in mental health treatment, potentially boosting profitability and supporting sustainable growth.
Negative Factors
Negative Cash Flow
Persistent negative cash flow indicates reliance on external financing, which can strain resources and limit strategic flexibility, posing a risk to long-term financial stability if not addressed.
Regulatory Complexities
Regulatory complexities in acquiring medical facilities could delay expansion plans and increase operational costs, impacting the company's growth trajectory and strategic execution.
Low Cash Reserves
Low cash reserves limit the company's ability to invest in growth initiatives and weather financial challenges, potentially hindering its ability to capitalize on strategic opportunities.

NRX Pharmaceuticals (NRXP) vs. SPDR S&P 500 ETF (SPY)

NRX Pharmaceuticals Business Overview & Revenue Model

Company DescriptionNRX Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, develops novel therapeutics for the treatment of central nervous system disorders and life-threatening pulmonary diseases. Its products include ZYESAMI, an investigational drug that has completed a Phase IIb/III clinical study for COVID-19 related respiratory failure; and NRX-100 and NRX-101 oral therapeutics for the treatment of bipolar depression in patients with acute suicidal behavior/ideation and sub-acute suicidal ideation and behavior. The company was founded in 2015 and is based in Wilmington, Delaware.
How the Company Makes MoneyNRX Pharmaceuticals makes money primarily through the development and commercialization of its pharmaceutical products. The company's revenue streams include partnerships with other pharmaceutical companies for drug development and distribution, as well as potential sales from its proprietary drugs once they receive regulatory approval. Additionally, NRX Pharmaceuticals may engage in licensing agreements, where they receive upfront payments, milestone payments, and royalties based on the sales performance of their licensed products. The company's earnings are also influenced by its ability to secure funding through investments, grants, or collaborations geared towards advancing its research and development efforts.

NRX Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 17, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 26, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant advancements in drug development and clinical progress, along with strong financial positioning and strategic expansions in clinic operations. However, there were challenges such as increased operational losses and limited initial revenue. Despite these challenges, the overall sentiment is optimistic due to the transformative progress and potential for substantial growth.
Q3-2025 Updates
Positive Updates
Transformative Progress and Drug Approvals
Advanced programs with drug approval applications in process for KETAFREE, NRX-100, and NRX-101. Expanded NRX-101 pipeline and closed on multiple acquisition targets for a network of interventional psychiatric clinics HOPE Therapeutics.
Positive Clinical Data
Real-world data showed an 87% treatment response and 72% remission from severe depression following a single day of treatment with TMS and low-dose D-cycloserine.
Revenue Generation and Clinic Expansion
Initiated revenue generation upon closing of acquisition of Dura Medical clinics. Plan to grow from 2 to 6 or more clinics by year-end with anticipated strong revenue growth.
Financial Stability and Investor Support
Stronger balance sheet with $10.3 million in cash and cash equivalents. Secured operating capital sufficient to fund operations through 2026.
Innovative Treatment Protocols
Launch of 1-day TMS treatment for severe depression using the ONE-D protocol in Florida.
Negative Updates
Increased Loss from Operations
Reported a loss of $4 million for the quarter, up from $3 million in the same quarter of 2024, primarily due to increased R&D expenses and general administrative costs.
Limited Initial Revenue
First-time revenue was relatively modest at $240,000, reflecting only 22 days of operations in a single clinic group.
Company Guidance
During the NRx Pharmaceuticals' Q3 2025 earnings call, the company highlighted several key metrics and developments that signal transformative progress. NRx reported its first-ever quarterly revenue of approximately $240,000, following the acquisition of Dura Medical clinics. They anticipate expanding from 2 to 6 clinics by year-end and expect significant revenue growth, supported by a current cash position of $10.3 million. The company is advancing three drug approval applications, including KETAFREE and NRX-101, which has shown an 87% treatment response and 72% remission rate in severe depression cases when combined with transcranial magnetic stimulation (TMS). NRx also secured operating capital sufficient to fund operations through 2026, aiming to drive long-term shareholder value and address the national suicide crisis.

NRX Pharmaceuticals Financial Statement Overview

Summary
NRX Pharmaceuticals faces significant financial challenges, with ongoing net losses and negative equity. Despite typical early-stage biotech challenges, the company must improve revenue generation and manage cash flow better.
Income Statement
10
Very Negative
NRX Pharmaceuticals shows consistent net losses and zero revenue over the years, leading to negative EBIT and EBITDA margins. There is no revenue growth, which is typical for early-stage biotech firms focusing on R&D and product development. The company faces challenges in transitioning from R&D to revenue generation.
Balance Sheet
20
Very Negative
The balance sheet reveals negative stockholders' equity and high liabilities compared to assets, indicating financial instability. The debt-to-equity ratio is not calculable due to negative equity, suggesting high financial risk. However, the absence of debt in the latest report is a slight positive aspect.
Cash Flow
15
Very Negative
Operating cash flow remains negative, reflecting ongoing cash burn without incoming revenue. The free cash flow is also negative, indicating the company relies on financing activities for liquidity. This cash flow scenario is common in biotech companies at the research stage.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue242.00K0.000.000.000.000.00
Gross Profit144.00K-5.00K-5.00K-4.00K-2.00K-2.00K
EBITDA-38.02M-24.04M-30.02M-39.75M-93.04M-51.72M
Net Income-38.06M-25.13M-30.15M-39.75M-93.06M-51.78M
Balance Sheet
Total Assets15.00M3.65M7.32M25.82M32.73M2.94M
Cash, Cash Equivalents and Short-Term Investments7.18M1.44M4.59M20.05M27.61M1.86M
Total Debt347.00K6.58M9.16M10.53M518.00K797.00K
Total Liabilities40.75M26.87M19.05M18.41M11.92M46.71M
Stockholders Equity-25.75M-23.22M-11.73M7.41M20.81M-43.77M
Cash Flow
Free Cash Flow-11.86M-10.64M-21.66M-39.77M-37.71M-2.27M
Operating Cash Flow-11.86M-10.64M-21.66M-39.76M-37.70M-2.27M
Investing Cash Flow-2.56M0.00-3.00K-10.00K-7.00K-2.00K
Financing Cash Flow19.96M7.49M6.20M32.21M63.46M3.25M

NRX Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.34
Price Trends
50DMA
2.90
Negative
100DMA
2.84
Negative
200DMA
2.65
Negative
Market Momentum
MACD
-0.22
Positive
RSI
43.16
Neutral
STOCH
36.70
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NRXP, the sentiment is Negative. The current price of 2.34 is below the 20-day moving average (MA) of 2.48, below the 50-day MA of 2.90, and below the 200-day MA of 2.65, indicating a bearish trend. The MACD of -0.22 indicates Positive momentum. The RSI at 43.16 is Neutral, neither overbought nor oversold. The STOCH value of 36.70 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for NRXP.

NRX Pharmaceuticals Risk Analysis

NRX Pharmaceuticals disclosed 102 risk factors in its most recent earnings report. NRX Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

NRX Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$64.95M-2.69-71.42%-38.81%-76.96%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$65.13M-1.22-9.32%
44
Neutral
$76.01M-1.47-172.70%
38
Underperform
$55.33M-0.74-122.43%-100.00%-8.30%
38
Underperform
$75.00M
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
NRXP
NRX Pharmaceuticals
2.34
1.05
81.40%
CRVO
CervoMed
9.94
0.78
8.52%
COEP
Coeptis Therapeutics Holdings
18.80
14.88
379.59%
HOWL
Werewolf Therapeutics
0.98
-0.99
-50.25%
OKYO
OKYO Pharma Limited Sponsored ADR
1.95
0.91
87.50%
CAMP
CAMP4 Therapeutics Corporation
3.62
-1.07
-22.81%

NRX Pharmaceuticals Corporate Events

Business Operations and StrategyFinancial Disclosures
NRX Pharmaceuticals Reports 2024 Financial Results and Strategy
Positive
Mar 21, 2025

NRx Pharmaceuticals announced its financial results for the fourth quarter and full year 2024, highlighting significant advancements in its drug development and corporate strategy. The company initiated the filing of a New Drug Application for NRX-100 for suicidal depression and plans to file for NRX-101 for bipolar depression. Additionally, NRx Pharmaceuticals is negotiating licensing agreements for NRX-100 and pursuing acquisitions to establish a national network of interventional psychiatry centers. These efforts aim to strengthen the company’s position in the mental health treatment market and potentially increase its profitability by the end of 2025.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 25, 2025