Positive Recognition for REZPEG
The Nobel Prize in Physiology or Medicine acknowledged the Phase Ib data for REZPEG in atopic dermatitis and psoriasis as part of the background documents for the award, highlighting the significance of Nektar's research.
Strong Financial Position
Nektar ended the third quarter of 2025 with $270.2 million in cash and investments, and no debt. The year-end cash guidance was increased to approximately $240 million, extending the cash runway into the second quarter of 2027.
Promising Phase IIb Results for REZPEG in Atopic Dermatitis
The RESOLVE-AD Phase IIb study showed statistical significance in all REZPEG arms versus placebo in reducing EASI scores. There is also an upcoming presentation of asthma-related data at the ACAAI meeting.
Advancement in Alopecia Areata
The Phase IIb RESOLVE-AA study in alopecia areata is on track, with results expected in December 2025. Positive results could position REZPEG as the first biologic treatment in this indication.
Pipeline Progress
Nektar's pipeline includes additional studies like the Phase II study of REZPEG in type 1 diabetes and the TNFR2 agonist program, with the potential for clinical advancement in 2026.