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Merus NV (MRUS)
NASDAQ:MRUS
Afatinib Oral Tablet, Enzalutamide Pill, Abiraterone Acetate Tablets, Mcla-128
Metastatic Castration-Resistant Prostate Cancer, Nsclc Harboring Nrg1 Fusion
Phase II
Active Not Recruiting
Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers
Oct 14, 2022
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Chemotherapy, Osimertinib, Mcla-129
Colorectal Cancer, Gastric Cancer, Head And Neck Squamous Cell Carcinoma, Esophageal Squamous Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic
Phase I/II
Recruiting
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
Apr 09, 2021
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Mcla-145, Pembrolizumab (Keytruda)
Advanced Cancer, Solid Tumor, Adult, B-Cell Lymphoma, Adult
Phase I
Completed
A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies
Apr 15, 2019
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Mcla-158, Mcla-158 + Pembrolizumab, Mcla-158 + Folfiri, Mcla-158 + Folfox
Colorectal Cancer, Gastric Cancer, Esophageal Cancer, Head And Neck Squamous Cell Carcinoma, Nsclc, Hnscc, Advanced/Metastatic Solid Tumors, Gastroesophageal-Junction Cancer
Phase I/II
Recruiting
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Apr 04, 2018
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Vinorelbine, Trastuzumab, Endocrine Therapy, Zenocutuzumab
Breast Cancer Metastatic
Phase II
Completed
MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.
Oct 11, 2017
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Mcla-117 Bispecific Antibody
Acute Myeloid Leukemia, Acute Myelogenous Leukemia
Phase I
Terminated
MCLA-117 in Acute Myelogenous Leukemia
Jan 26, 2017
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Merus NV (MRUS) have in its pipeline
MRUS is currently developing the following drugs: Pembrolizumab, Petosemtamab, Petosemtamab, Investigator's Choice, Afatinib Oral Tablet, Enzalutamide Pill, Abiraterone Acetate Tablets, Mcla-128. These drug candidates are in various stages of clinical development as the company works toward FDA approval.