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Lantheus (LNTH)
NASDAQ:LNTH

Lantheus (LNTH) AI Stock Analysis

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LN

Lantheus

(NASDAQ:LNTH)

80Outperform
Lantheus earns a strong overall score due to its robust financial performance, strategic acquisitions, and optimistic future guidance. While technical indicators show mixed signals, and valuation is moderate, the company's strategic initiatives and strong financial health suggest a positive outlook.
Positive Factors
Market Position
Despite competition, PYLARIFY has maintained its market leading position.
Revenue Growth
Definity revenues in 4Q beat consensus and estimates by 14% and 9%, respectively.
Strategic Acquisitions
Lantheus' recent strategic acquisitions of Life Molecular Imaging and Evergreen Theragnostics position the company well for future growth.
Negative Factors
Competitive Pressure
The initial guidance for 2025 suggests Pylarify can achieve low- to mid-single-digit growth despite reimbursement and competitive pressures.
Earnings Forecast
The updated earnings per share for the full year 2025 are lower than previous estimates.
Revenue Guidance
FY25 total revenue guidance was slightly below consensus expectations.

Lantheus (LNTH) vs. S&P 500 (SPY)

Lantheus Business Overview & Revenue Model

Company DescriptionLantheus Holdings, Inc. develops, manufactures, and commercializes diagnostic and therapeutic products that assist clinicians in the diagnosis and treatment of heart, cancer, and other diseases worldwide. It provides DEFINITY, a microbubble ultrasound enhancing agent used in ultrasound exams of the heart; TechneLite, a technetium generator for nuclear medicine; Xenon-133 to assess pulmonary function; Neurolite to identify the area within the brain where blood flow has been blocked or reduced due to stroke; Cardiolite, an injectable Tc-99m-labeled imaging agent; Thallium-201 to detect cardiovascular disease; and Gallium-67 to detect various infections and cancerous tumors. The company also offers AZEDRA, a radiotherapeutic to treat adult and pediatric patients; Automated Bone Scan Index that calculates the disease burden of prostate cancer by quantifying the hotspots on bone scans; and Cobalt (Co 57), a non-pharmaceutical radiochemical; RELISTOR for opioid-induced constipation; and PYLARIFY for visualization of lymph nodes, bone, and soft tissue metastases to determine the presence or absence of recurrent and/or metastatic prostate cancer. It also develops flurpiridaz F 18 to assess blood flow to the heart; 1095, a PSMA-targeted iodine-131 labeled small molecule; LMI 1195 for neuroblastoma tumors in pediatric and adults; PYLARIFY AI, an AI-based medical device software to perform standardized quantitative assessment of PSMA PET/CT images in prostate cancer; and leronlimab, an investigational humanized monoclonal antibody. The company serves radio pharmacies, distributors, integrated delivery networks, hospitals, clinics, and group practices. It has strategic partnerships with NanoMab Technology Limited; Bausch Health Companies, Inc.; GE Healthcare Limited; Curium; Bayer AG; CytoDyn Inc.; ROTOP; FUJIFILM; Regeneron Pharmaceuticals, Inc.; and POINT Biopharma US Inc. The company was founded in 1956 and is headquartered in North Billerica, Massachusetts.
How the Company Makes MoneyLantheus generates revenue primarily through the sale of its diagnostic and therapeutic imaging products. A significant portion of its income comes from the sales of DEFINITY, a widely used ultrasound contrast agent. Additionally, the company earns from its portfolio of radiopharmaceuticals, which includes products for PET and SPECT imaging procedures. Lantheus has established partnerships and distribution agreements which help in expanding the reach of its products to healthcare providers globally. Revenue is also supported by ongoing research and development efforts that lead to new product offerings and enhancements of existing products, ensuring a steady pipeline of innovative solutions in the medical imaging field.

Lantheus Financial Statement Overview

Summary
Lantheus exhibits strong financial health with robust revenue growth, high profitability margins, low leverage, and excellent cash flow generation. The income statement shows a significant revenue increase of 18.28%, and the balance sheet reflects minimal debt with a low debt-to-equity ratio. Cash flow management is effective with a free cash flow growth of 90.52%.
Income Statement
88
Very Positive
Lantheus demonstrates strong revenue growth, with a 18.28% increase from 2023 to 2024. The gross profit margin for 2024 is healthy at 64.43%, indicating effective cost management and profitability. The net profit margin improved to 20.37% in 2024, showing enhanced profitability. EBIT and EBITDA margins are robust at 29.79% and 29.79%, respectively, reflecting operational efficiency.
Balance Sheet
85
Very Positive
The company maintains a solid financial position with a low debt-to-equity ratio of 0.001, indicating minimal leverage. The return on equity is impressive at 28.72%, reflecting strong profitability relative to shareholder investments. The equity ratio of 54.94% indicates a healthy balance between equity and assets, suggesting financial stability.
Cash Flow
92
Very Positive
Lantheus has shown significant improvement in its free cash flow, growing by 90.52% from 2023 to 2024. Operating cash flow to net income ratio is strong at 1.74, indicating efficient cash generation from operations. The free cash flow to net income ratio of 1.58 underscores effective cash management and the ability to fund operations and growth.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
1.53B1.30B935.06M425.21M339.41M
Gross Profit
988.29M709.54M581.70M187.69M138.76M
EBIT
456.98M364.64M-13.44M-76.09M-4.20M
EBITDA
515.27M491.00M81.83M-25.00M22.69M
Net Income Common Stockholders
312.44M326.66M28.07M-71.28M-13.47M
Balance SheetCash, Cash Equivalents and Short-Term Investments
912.81M713.66M415.65M98.51M79.61M
Total Assets
1.98B1.65B1.32B863.78M869.82M
Total Debt
974.00K616.95M558.07M174.76M218.40M
Net Debt
-911.84M-96.71M142.41M76.25M138.79M
Total Liabilities
892.33M835.26M874.11M399.35M355.62M
Stockholders Equity
1.09B815.89M447.15M464.44M514.21M
Cash FlowFree Cash Flow
493.13M258.70M263.43M41.78M3.92M
Operating Cash Flow
544.75M305.26M281.78M53.92M16.40M
Investing Cash Flow
-226.01M5.94M-276.55M3.68M-4.91M
Financing Cash Flow
-118.54M-13.06M311.69M-39.33M-21.86M

Lantheus Technical Analysis

Technical Analysis Sentiment
Positive
Last Price103.64
Price Trends
50DMA
95.55
Positive
100DMA
93.71
Positive
200DMA
98.79
Positive
Market Momentum
MACD
1.14
Negative
RSI
54.83
Neutral
STOCH
69.60
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LNTH, the sentiment is Positive. The current price of 103.64 is above the 20-day moving average (MA) of 98.52, above the 50-day MA of 95.55, and above the 200-day MA of 98.79, indicating a bullish trend. The MACD of 1.14 indicates Negative momentum. The RSI at 54.83 is Neutral, neither overbought nor oversold. The STOCH value of 69.60 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for LNTH.

Lantheus Risk Analysis

Lantheus disclosed 50 risk factors in its most recent earnings report. Lantheus reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lantheus Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
80
Outperform
$6.82B23.1432.82%18.32%-5.33%
RDRDY
77
Outperform
$11.75B18.1918.51%0.59%13.26%1.33%
75
Outperform
$10.07B31.3614.16%24.81%33.67%
53
Neutral
$3.39B-3.53%4.51%-6.05%-1677.05%
52
Neutral
$9.18B-3.24%6.24%-4.58%-1269.23%
51
Neutral
$5.20B3.26-40.34%2.93%17.68%1.94%
50
Neutral
$16.04B-25.44%4.34%-206.85%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LNTH
Lantheus
103.64
38.44
58.96%
RDY
Dr Reddy's Laboratories
14.00
-0.73
-4.96%
VTRS
Viatris
8.03
-2.96
-26.93%
NBIX
Neurocrine
105.76
-32.00
-23.23%
PRGO
Perrigo Company
24.89
-5.17
-17.20%
TEVA
Teva Pharmaceutical
14.72
1.47
11.09%

Lantheus Earnings Call Summary

Earnings Call Date: Feb 26, 2025 | % Change Since: 29.47% | Next Earnings Date: May 7, 2025
Earnings Call Sentiment Positive
Lantheus reported strong revenue growth driven by Pylarify and DEFINITY, alongside strategic acquisitions expected to bolster future growth. However, challenges include increased operating expenses and a net loss for the quarter. Despite these challenges, the company remains optimistic about its pipeline and strategic direction.
Highlights
Record-Breaking Revenue and Growth
Lantheus achieved $1.534 billion in revenue for the full year 2024, an increase of 18.3%, with Pylarify sales surpassing $1 billion, establishing it as the first-ever radio diagnostic blockbuster.
Strategic Acquisitions
Lantheus announced acquisitions of Life Molecular Imaging and Evergreen Theragnostics, expected to enhance radiopharmaceutical capabilities and drive sustained double-digit revenue growth beginning in 2026.
Strong Performance of DEFINITY
DEFINITY, the leading ultrasound enhancing agent, achieved fourth quarter net sales of $86.2 million, up 17.9% year-over-year.
CMS Policy Favorable for Radiopharmaceuticals
The new CMS payment policy provides separate payment for innovative radiopharmaceutical diagnostics, benefiting products like Pylarify.
Future Pipeline Potential
Lantheus is excited about its pipeline, including MK-6240 and NAV-4694 for Alzheimer's diagnostics, and expects to file NDAs in 2025 and 2026.
Lowlights
Decreased Strategic Partnerships and Other Revenue
Strategic partnerships and other revenue were down 66.2% for the fourth quarter due to the inclusion of a previous RELISTOR royalty milestone.
Operating Expense Increase
Operating expenses were 29.1% of net revenue, up 670 basis points from the prior year, mainly due to increased R&D investments and acquisition-related expenses.
Net Loss for the Quarter
Lantheus reported a net loss of $11.8 million for the fourth quarter, affected by significant expenses tied to potential acquisitions.
Company Guidance
During the Lantheus Fourth Quarter and Full Year 2024 Conference Call, the company provided guidance for 2025, anticipating a full-year net revenue in the range of $1.54 billion to $1.61 billion, reflecting growth of 1% to 5% over 2024. Pylarify, a leading PSMA PET imaging agent, is expected to achieve low to mid-single-digit growth, while DEFINITY is projected to grow at a similar rate despite facing headwinds. The company forecasts a gross profit margin similar to 2024's 68% and anticipates fully diluted adjusted earnings per share between $7.00 and $7.20, an increase of 3.5% to 6.5%. Lantheus plans to generate $550 million to $600 million in free cash flow and highlight the potential for sustained double-digit revenue growth starting in 2026, driven by strategic transactions and pipeline expansions.

Lantheus Corporate Events

M&A TransactionsBusiness Operations and Strategy
Lantheus Completes Acquisition of Evergreen Theragnostics
Positive
Apr 1, 2025

On April 1, 2025, Lantheus Holdings, Inc. completed its acquisition of Evergreen Theragnostics, Inc., a move that enhances Lantheus’ capabilities across the radiopharmaceutical value chain. The acquisition, initially announced on January 28, 2025, includes Evergreen’s OCTEVY, a PET diagnostic imaging agent for neuroendocrine tumors, and a portfolio of theranostic pairs, as well as Evergreen’s radioligand therapy manufacturing infrastructure. This strategic acquisition positions Lantheus to better meet market demands and drive innovation, with potential milestone payments up to $727.5 million contingent on future achievements.

Executive/Board ChangesBusiness Operations and Strategy
Lantheus Appoints Dr. Morrow to Board of Directors
Positive
Jan 30, 2025

Lantheus Holdings, Inc. announced the appointment of Phuong Khanh (P.K.) Morrow, M.D., to its Board of Directors, effective February 1, 2025. Dr. Morrow, a seasoned pharmaceutical executive with extensive oncology expertise, will serve as an independent director and a member of the Science and Technology Committee. Her appointment comes during a period of growth for Lantheus, as it aims to enhance its strategic initiatives and innovative efforts in radiopharmaceuticals. Dr. Morrow’s experience is expected to bolster the company’s research and development capabilities, aligning with its vision to improve patient outcomes.

M&A Transactions
Lantheus to Acquire Evergreen Theragnostics for $250 Million
Positive
Jan 28, 2025

On January 27, 2025, Lantheus Medical Imaging, a subsidiary of Lantheus Holdings, announced an agreement to acquire Evergreen Theragnostics for $250 million upfront and potential milestone payments of up to $752.5 million. This acquisition, expected to close in the second half of 2025, aims to enhance Lantheus’ capabilities as a fully integrated radiopharmaceutical company by adding Evergreen’s manufacturing infrastructure and expanding its oncology diagnostic pipeline. The addition of Evergreen’s assets, such as OCTEVY, a diagnostic agent targeting neuroendocrine tumors, is anticipated to complement Lantheus’ existing therapeutic offerings and strengthen its industry leadership. The merger is subject to customary closing conditions, including regulatory approvals.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.