Clinical Efficacy And DurabilityUpdated trial results report rapid onset of symptom relief with high rates of complete response and sustained disease control in extension studies, supporting the therapy's efficacy and durability.
Program De-risking And Development ClarityIndependent review and investigations attributed anomalous nonresponse to misdiagnosis and site conduct rather than drug product, enabling clearer dose selection for the planned adaptive Phase 2b/3 program and drawing potential partner interest.
Safety And TolerabilitySafety data indicate the therapy is generally well tolerated, with KIT-related adverse events described as infrequent, low-grade, and transient, improving the clinical risk profile.