Clinical Site IssuesManagement has identified one clinical site where improper injection methods were used, which affected the data and will no longer be used for briquilimab trials.
Enrollment DelaysJSPR has taken a more careful approach to patient enrollment in BEACON, slowing the pace of the enrollment and shifting the timing of the BEACON update.
Patient Enrollment ChallengesCohorts 8 and 9 in the BEACON trial were impacted by poor patient selection, leading to the conclusion that many patients did not have mast cell-driven disease.