Competitive DisadvantageThe expected start for the Ph2b CSU study has now been pushed out to mid-'26, placing Jasper ~18-24 months behind the competition.
Operational ChallengesA strategic shift has led to a corporate restructuring, including a 50% workforce reduction and a new interim CMO, to fully concentrate resources on urticaria.
Trial DelaysJSPR has taken a more careful approach to patient enrollment in BEACON, slowing the pace of the enrollment and shifting the timing of the BEACON update.