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Santen Pharmaceutical Co Ltd (JP:4536)
:4536
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Santen Pharmaceutical Co (4536) AI Stock Analysis

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JP:4536

Santen Pharmaceutical Co

(4536)

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Outperform 72 (OpenAI - 5.2)
Rating:72Outperform
Price Target:
¥2,106.00
▲(31.87% Upside)
Action:ReiteratedDate:02/07/26
The score is driven primarily by solid financial health and recovering profitability supported by low leverage, partially offset by declining revenue and a recent weakening in TTM cash flow. Technicals are neutral-to-constructive with longer-term trend support but limited near-term momentum, while valuation appears fair rather than compelling.
Positive Factors
Conservative balance sheet
Santen's very low debt-to-equity (around 0.10–0.13) and large equity base provide durable financial flexibility. This conservative capital structure supports continued R&D and manufacturing investment, smooths funding for launches, and reduces refinancing risk over the next several months.
Negative Factors
Declining revenue
Revenue has declined (roughly -4.6% in the provided metric) and the income statement notes softer top-line trends. Persistent revenue contraction can erode scale, reduce pricing power in regulated markets, and limit resources for new launches or geographic rollouts if not reversed.
Read all positive and negative factors
Positive Factors
Negative Factors
Conservative balance sheet
Santen's very low debt-to-equity (around 0.10–0.13) and large equity base provide durable financial flexibility. This conservative capital structure supports continued R&D and manufacturing investment, smooths funding for launches, and reduces refinancing risk over the next several months.
Read all positive factors

Santen Pharmaceutical Co (4536) vs. iShares MSCI Japan ETF (EWJ)

Santen Pharmaceutical Co Business Overview & Revenue Model

Company Description
Santen Pharmaceutical Co., Ltd. (Ticker: 4536) is a global pharmaceutical company headquartered in Japan, specializing in the research, development, manufacturing, and marketing of products primarily for ophthalmology. Established in 1890, Santen ...
How the Company Makes Money
Santen makes money primarily by selling ophthalmic prescription pharmaceuticals. Its core revenue stream is product sales of branded eye-drop and other ocular therapies, which are generated through: (1) Domestic sales: sales to wholesalers, hospit...

Santen Pharmaceutical Co Financial Statement Overview

Summary
Strong balance sheet with low leverage and improving profitability after the 2023 loss year, but revenue is declining and TTM operating/free cash flow has stepped down, which raises execution risk if sales softness persists.
Income Statement
74
Positive
Balance Sheet
82
Very Positive
Cash Flow
67
Positive
BreakdownTTMMar 2026Mar 2025Mar 2024Mar 2023Mar 2022
Income Statement
Total Revenue287.99B300.00B301.96B279.04B266.26B249.60B
Gross Profit155.02B163.21B163.88B156.57B146.85B140.73B
EBITDA59.47B74.18B70.08B49.26B53.03B54.99B
Net Income30.61B36.26B26.64B-14.95B27.22B9.31B
Balance Sheet
Total Assets401.16B409.28B435.70B421.18B459.98B405.29B
Cash, Cash Equivalents and Short-Term Investments61.54B93.00B94.58B57.90B83.01B62.89B
Total Debt36.15B33.95B35.16B35.96B22.00B10.15B
Total Liabilities118.72B124.10B130.33B127.88B123.13B95.64B
Stockholders Equity283.38B286.24B306.05B293.98B337.49B310.18B
Cash Flow
Free Cash Flow35.53B54.27B63.33B19.87B28.70B34.67B
Operating Cash Flow41.41B60.93B72.65B37.15B46.04B38.81B
Investing Cash Flow-12.59B-8.22B-6.14B-26.78B-35.17B-53.35B
Financing Cash Flow-48.70B-53.31B-34.03B-37.22B5.56B-16.68B

Santen Pharmaceutical Co Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1597.00
Price Trends
50DMA
1726.72
Positive
100DMA
1680.66
Positive
200DMA
1626.56
Positive
Market Momentum
MACD
27.34
Positive
RSI
49.18
Neutral
STOCH
4.46
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4536, the sentiment is Positive. The current price of 1597 is below the 20-day moving average (MA) of 1798.86, below the 50-day MA of 1726.72, and below the 200-day MA of 1626.56, indicating a neutral trend. The MACD of 27.34 indicates Positive momentum. The RSI at 49.18 is Neutral, neither overbought nor oversold. The STOCH value of 4.46 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4536.

Santen Pharmaceutical Co Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
¥53.86B12.813.22%11.84%-5.68%
74
Outperform
¥126.06B9.267.81%1.78%3.00%36.97%
72
Outperform
¥530.26B16.6610.89%2.30%-4.61%17.36%
68
Neutral
¥7.61B-11.77-44.99%-199.29%
67
Neutral
¥4.30T15.487.97%3.61%11.87%474.27%
62
Neutral
¥248.64B5.594.38%2.03%4.10%199.63%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4536
Santen Pharmaceutical Co
1,650.50
275.13
20.00%
JP:4503
Astellas Pharma
2,306.00
925.98
67.10%
JP:7780
Menicon Co
1,644.00
242.38
17.29%
JP:8086
Nipro
1,533.50
263.94
20.79%
JP:4890
Tsubota Laboratory Incorporated
297.00
-115.00
-27.91%
JP:5889
Japan Eyewear Holdings Co.,Ltd.
2,250.00
119.51
5.61%

Santen Pharmaceutical Co Corporate Events

Santen Pharmaceutical Posts Lower Nine-Month Earnings but Raises Annual Dividend and Maintains Outlook
Feb 5, 2026
Santen Pharmaceutical reported weaker consolidated results for the nine months ended December 31, 2025, with revenue declining 5.4% year on year to ¥210.8 billion and core operating profit dropping 20.3%, reflecting profit pressure despite a ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 07, 2026