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Heartseed, Inc. (JP:219A)
:219A
Japanese Market

Heartseed, Inc. (219A) AI Stock Analysis

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JP:219A

Heartseed, Inc.

(219A)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
¥1,361.00
▼(-24.56% Downside)
Heartseed, Inc. faces significant challenges with profitability and cash flow management despite strong revenue growth. The technical indicators suggest a bearish trend, and the high P/E ratio points to potential overvaluation. The absence of earnings call data and corporate events limits further insights.
Positive Factors
Revenue Growth
The significant revenue growth indicates strong market demand and successful product development, which can drive long-term business expansion and investor confidence.
Balance Sheet Health
A robust balance sheet with minimal leverage provides financial flexibility and reduces risk, supporting sustainable growth and strategic investments.
Innovative Business Model
The focus on cutting-edge regenerative medicine positions Heartseed as a leader in innovative therapies, potentially capturing significant market share in cardiovascular treatments.
Negative Factors
Profitability Challenges
Persistent negative margins highlight operational inefficiencies, which could hinder profitability and require strategic adjustments to achieve sustainable financial health.
Cash Flow Management
Negative cash flow suggests difficulties in funding operations internally, which may necessitate external financing and impact long-term financial stability.
Unprofitability
Continued unprofitability poses a risk to financial sustainability, requiring strategic initiatives to improve cost management and revenue generation.

Heartseed, Inc. (219A) vs. iShares MSCI Japan ETF (EWJ)

Heartseed, Inc. Business Overview & Revenue Model

Company DescriptionHeartseed, Inc. engages in the provision of cardiac regenerative medicine. The company was founded by Keiichi Fukuda, Takumi Akiyama, Toshiharu Furukawa and Yutaro Kasai on November 30, 2015 and is headquartered in Tokyo, Japan.
How the Company Makes MoneyHeartseed, Inc. generates revenue primarily through the development and commercialization of its therapeutic products. The company’s revenue model includes several key streams: licensing agreements with pharmaceutical companies, grant funding for research and development, and potential milestone payments associated with clinical trial progress. Additionally, partnerships with academic institutions and healthcare organizations enhance its research capabilities and may provide funding opportunities. As the company advances its products through clinical trials and approaches regulatory approval, it stands to gain substantial financial returns from product sales and royalties.

Heartseed, Inc. Financial Statement Overview

Summary
Heartseed, Inc. shows strong revenue growth but faces challenges with profitability and cash flow management. The balance sheet is robust with minimal leverage, yet operational inefficiencies and cash flow issues pose risks.
Income Statement
30
Negative
Heartseed, Inc. shows a significant increase in total revenue from the previous year, demonstrating strong growth potential. However, the company faces challenges with negative EBIT and EBITDA margins, indicating operational inefficiencies. The net profit margin is also negative, reflecting ongoing unprofitability.
Balance Sheet
50
Neutral
The company maintains a strong equity position with an equity ratio of 93.7%, indicating financial stability. The debt-to-equity ratio is low at 0.001, suggesting minimal leverage risk. However, the high net loss impacts the return on equity negatively.
Cash Flow
35
Negative
Operating cash flow remains negative, highlighting cash management challenges. The company has a negative free cash flow, although it improved slightly from the previous year. The operating cash flow to net income ratio is below 1, suggesting inefficiencies in converting revenue into cash.
BreakdownTTMDec 2024Dec 2023Dec 2022
Income Statement
Total Revenue2.64B873.61M344.73M499.06M
Gross Profit2.61B873.61M344.73M499.06M
EBITDA610.27M-776.36M-1.45B-1.41B
Net Income519.32M-812.73M-1.47B-1.41B
Balance Sheet
Total Assets7.71B7.07B5.72B4.94B
Cash, Cash Equivalents and Short-Term Investments6.92B5.30B4.59B3.99B
Total Debt2.04M5.39M11.58M30.98M
Total Liabilities508.69M444.35M450.19M208.45M
Stockholders Equity7.20B6.62B5.27B4.73B
Cash Flow
Free Cash Flow0.00-1.41B-1.13B-1.92B
Operating Cash Flow0.00-1.34B-797.93M-1.92B
Investing Cash Flow0.00-67.13M-425.69M-994.00K
Financing Cash Flow0.002.12B1.85B-22.16M

Heartseed, Inc. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1804.00
Price Trends
50DMA
1880.62
Positive
100DMA
2107.41
Negative
200DMA
2555.63
Negative
Market Momentum
MACD
24.25
Positive
RSI
46.27
Neutral
STOCH
6.01
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:219A, the sentiment is Negative. The current price of 1804 is below the 20-day moving average (MA) of 1960.05, below the 50-day MA of 1880.62, and below the 200-day MA of 2555.63, indicating a neutral trend. The MACD of 24.25 indicates Positive momentum. The RSI at 46.27 is Neutral, neither overbought nor oversold. The STOCH value of 6.01 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:219A.

Heartseed, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
85
Outperform
¥33.95B11.956.29%-12.03%-19.61%
58
Neutral
¥79.82B-32.212.71%7.15%-454.41%
57
Neutral
¥21.93B-47.52-5.65%-469.19%
55
Neutral
¥65.25B-97.231772.85%16.16%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
¥43.50B72.89
43
Neutral
¥18.18B-9.5011.34%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:219A
Heartseed, Inc.
1,903.00
95.00
5.25%
JP:4552
JCR Pharmaceuticals Co., Ltd.
645.00
110.56
20.69%
JP:4595
Mizuho Medy Co., Ltd.
1,782.00
360.04
25.32%
JP:4599
StemRIM Inc.
290.00
-26.00
-8.23%
JP:4894
Cuorips Inc.
7,910.00
3,490.00
78.96%
JP:7774
Japan Tissue Engineering Co., Ltd.
540.00
48.00
9.76%

Heartseed, Inc. Corporate Events

Heartseed Inc. Revises Financial Forecast with Positive Outlook
Dec 11, 2025

Heartseed Inc. announced a revision of its full-year financial forecast for the fiscal year ending December 31, 2025, due to lower-than-expected research and development expenses. The revised forecast indicates significant improvements in operating, ordinary, and net profits, suggesting a positive financial outlook for the company.

The most recent analyst rating on (JP:219A) stock is a Hold with a Yen1361.00 price target. To see the full list of analyst forecasts on Heartseed, Inc. stock, see the JP:219A Stock Forecast page.

Heartseed Inc. Reports Strong Financial Recovery
Dec 11, 2025

Heartseed Inc. reported significant financial improvement for the twelve months ending October 31, 2025, with net sales rising to 3,026 million yen from 873 million yen the previous year. The company achieved a net profit of 592 million yen compared to a loss in the prior year, indicating a strong recovery and positive outlook for stakeholders.

The most recent analyst rating on (JP:219A) stock is a Hold with a Yen1361.00 price target. To see the full list of analyst forecasts on Heartseed, Inc. stock, see the JP:219A Stock Forecast page.

Heartseed, Inc. Advances Cardiac Therapy Trial After Regulatory Approval
Nov 4, 2025

Heartseed, Inc. announced the completion of a 30-day review by the Pharmaceuticals and Medical Devices Agency for their clinical trial notification of the HS-005 therapy, allowing the trial to commence. The EMERALD study will evaluate the safety and efficacy of this therapy in treating severe heart failure, planning to enroll 14 patients. The company plans to start patient administration in 2026, with no changes to their current earnings forecast.

The most recent analyst rating on (JP:219A) stock is a Hold with a Yen1361.00 price target. To see the full list of analyst forecasts on Heartseed, Inc. stock, see the JP:219A Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 03, 2025