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iSpecimen (ISPC)
NASDAQ:ISPC
US Market

iSpecimen (ISPC) AI Stock Analysis

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ISPC

iSpecimen

(NASDAQ:ISPC)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
$0.32
▲(3.87% Upside)
The score is primarily held down by weak financial performance—sharp TTM revenue decline, materially worse margins, continued losses, and ongoing cash burn. Technicals also remain bearish with the stock below major moving averages and negative MACD. Corporate events are mixed, with continued Nasdaq bid-price compliance risk offset only partially by regained equity compliance and recent financing.
Positive Factors
Platform and network access
iSpecimen’s marketplace model links researchers, biopharma and a broad set of specimen providers, creating durable network effects. Persistent access to rare and diverse biospecimens supports repeat institutional customers, recurring transactions, and long-term revenue potential tied to medical research demand.
Low financial leverage
Very low debt reduces solvency risk and preserves the company’s capacity to raise more capital or restructure financing without heavy interest burdens. This balance-sheet flexibility is a lasting advantage when managing runway, pursuing strategic partnerships, or funding operational turnaround initiatives.
Completed Series C preferred financing
The $5.5M private placement materially strengthens near-term liquidity and extends runway, a structural improvement versus relying only on operating cash flow. Structured as senior convertible preferred, it provides capital while preserving operational continuity and enabling execution of strategic initiatives over coming months.
Negative Factors
Sharp revenue decline and margin compression
A steep TTM revenue drop and halved gross margins signal weakening demand or pricing/ mix pressure that undermines sustainable profitability. Restoring top-line growth and margin structure is essential for structural recovery; absent improvement, operating losses are likely to persist over the medium term.
Persistent negative operating cash flow
Consistent negative operating cash flow (~-$6.8M TTM) means the core business consumes capital rather than funds growth. This elevates reliance on external financing, risks dilution, and constrains investment in business development or platform improvements, threatening longer-term competitiveness if cash generation isn’t restored.
Nasdaq listing risk from low share price
A formal Nasdaq deficiency for minimum bid price is a structural governance and financing risk: potential delisting would impair liquidity and access to public capital, force management to pursue corporate actions (reverse split) and distract resources from core execution over the medium term.

iSpecimen (ISPC) vs. SPDR S&P 500 ETF (SPY)

iSpecimen Business Overview & Revenue Model

Company DescriptioniSpecimen Inc. provides technology that connects life science researchers who need human biofluids, tissues, and living cells for their research with biospecimens available in healthcare provider organizations worldwide. Its cloud-based technology enables scientists to search for specimens and patients across a network of hospitals, labs, biobanks, blood centers, and other healthcare organizations. The company develops and operates iSpecimen Marketplace, a proprietary online marketplace platform that connects medical researchers who need access to subjects, samples, and data with hospitals, laboratories, and other organizations who have access to them. It serves biopharmaceutical companies, in vitro diagnostic companies, and government/academic institutions. The company was incorporated in 2009 and is headquartered in Lexington, Massachusetts.
How the Company Makes MoneyiSpecimen generates revenue primarily through the sale of human biospecimens and associated data to researchers, pharmaceutical companies, and academic institutions. The company's revenue model is built on fees charged for the procurement and delivery of biospecimens, which can vary based on the type and quantity of samples requested. Key revenue streams include transactions for individual biospecimen orders, long-term supply agreements with biopharma companies, and collaborative projects that may involve custom sample collection services. Additionally, iSpecimen has established strategic partnerships with hospitals, clinics, and biobanks, enhancing its access to a wide array of biospecimens and driving growth in its revenue through increased sample availability and diversity.

iSpecimen Financial Statement Overview

Summary
iSpecimen faces significant financial challenges, including declining revenues, negative profitability, and cash flow issues. Despite some improvements in the balance sheet with reduced debt levels and improved equity ratios, the company's financial health remains weak, with persistent net losses and cash flow deficits. Strategic improvements are essential to stabilize and enhance financial performance.
Income Statement
18
Very Negative
The company has shown a declining trend in revenue and profitability. Gross Profit Margin decreased from 52.8% in 2020 to 42.9% in 2024. Net Profit Margins remain negative, with worsening EBIT and EBITDA margins, indicating operational inefficiency. Revenue has been declining from $11.13 million in 2021 to $9.29 million in 2024, showcasing negative growth.
Balance Sheet
44
Neutral
The balance sheet reflects a relatively high level of debt with a Debt-to-Equity Ratio of 0.09 in 2024, reduced from previous years. However, the negative equity in prior years raises concerns about financial stability. The equity ratio improved to 35.4% in 2024 from negative figures in earlier years, indicating some improvement in financial health.
Cash Flow
12
Very Negative
The company has consistently negative operating and free cash flows, with a significant cash burn. The operating cash flow to net income ratio is negative, highlighting issues in converting income into cash. Although free cash flow improved slightly in 2024 compared to previous years, it remains negative, indicating continued challenges in liquidity.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue3.35M9.29M9.93M10.40M11.14M8.18M
Gross Profit722.54K3.99M5.11M5.65M5.89M4.60M
EBITDA-9.47M-12.73M-8.80M-8.80M-5.86M-1.74M
Net Income-11.53M-12.50M-11.10M-10.25M-8.96M-4.65M
Balance Sheet
Total Assets9.00M9.35M15.82M24.62M35.72M6.21M
Cash, Cash Equivalents and Short-Term Investments2.78M1.88M5.01M15.31M27.74M695.91K
Total Debt281.44K312.17K196.24K185.85K3.42M12.77M
Total Liabilities5.92M6.04M6.08M4.31M5.93M33.49M
Stockholders Equity3.07M3.31M9.74M20.31M29.79M-27.28M
Cash Flow
Free Cash Flow-6.79M-8.30M-10.55M-9.01M-11.71M-1.39M
Operating Cash Flow-6.76M-8.26M-5.81M-5.82M-10.67M-288.38K
Investing Cash Flow-1.07M1.98M-7.23M-3.19M-1.04M-1.10M
Financing Cash Flow8.86M5.82M70.89K-3.42M38.75M2.03M

iSpecimen Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.31
Price Trends
50DMA
0.46
Negative
100DMA
0.76
Negative
200DMA
0.96
Negative
Market Momentum
MACD
-0.05
Negative
RSI
40.81
Neutral
STOCH
58.28
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ISPC, the sentiment is Negative. The current price of 0.31 is below the 20-day moving average (MA) of 0.34, below the 50-day MA of 0.46, and below the 200-day MA of 0.96, indicating a bearish trend. The MACD of -0.05 indicates Negative momentum. The RSI at 40.81 is Neutral, neither overbought nor oversold. The STOCH value of 58.28 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ISPC.

iSpecimen Risk Analysis

iSpecimen disclosed 72 risk factors in its most recent earnings report. iSpecimen reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

iSpecimen Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$14.97M-0.84-223.45%3.26%65.96%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$10.15M
43
Neutral
$5.67M-0.07-245.18%-27.66%13.18%
42
Neutral
$3.31M-0.05-296.20%-67.73%58.35%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ISPC
iSpecimen
0.33
-2.52
-88.42%
INBS
Intelligent Bio Solutions
15.60
2.50
19.08%
BGLC
BioNexus Gene Lab Corp
3.76
-0.04
-1.05%
MYNZ
Mainz Biomed B.V.
1.12
-3.53
-75.91%
BIAF
bioAffinity Technologies, Inc.
1.26
-20.46
-94.20%

iSpecimen Corporate Events

Shareholder Meetings
iSpecimen Postpones Annual Meeting Due to Lack Quorum
Neutral
Jan 5, 2026

On December 31, 2025, iSpecimen Inc. convened its 2025 annual meeting of stockholders but adjourned it after failing to achieve a quorum of shareholders needed to conduct business on the proposals previously circulated. The company plans to reconvene the annual meeting on January 23, 2026, maintaining November 3, 2025 as the record date, signaling an effort to secure sufficient shareholder participation to move forward with its proposed agenda.

The most recent analyst rating on (ISPC) stock is a Sell with a $0.28 price target. To see the full list of analyst forecasts on iSpecimen stock, see the ISPC Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
iSpecimen Completes Private Placement, Engages IR Consulting Firm
Positive
Jan 5, 2026

On December 31, 2025, iSpecimen Inc. completed a private placement of its Series C Convertible Non-Voting Preferred Stock and entered into a Consulting Agreement with IR Agency LLC to provide marketing, advertising, and investor communications services for an initial four-month term starting the same day. The consultant, acting as an independent contractor on a non-exclusive basis, received a $2 million cash fee funded from the private placement proceeds, and the agreement—which includes standard contractual protections and can be terminated at any time by either party—signals iSpecimen’s effort to strengthen its market visibility and investor outreach without engaging in securities solicitation activities.

The most recent analyst rating on (ISPC) stock is a Sell with a $0.28 price target. To see the full list of analyst forecasts on iSpecimen stock, see the ISPC Stock Forecast page.

Private Placements and Financing
iSpecimen raises capital via new Series C preferred
Neutral
Jan 2, 2026

On December 30, 2025, iSpecimen Inc. entered into a Securities Purchase Agreement with accredited investors to issue 6,875 shares of newly created Series C Convertible Non-Voting Preferred Stock, each with a stated value of $1,000 and sold at $800 per share, and on December 31, 2025 closed the transaction for aggregate gross proceeds of $5.5 million. The Series C preferred shares, which were structured to rank senior to common stock in dividends and liquidation and carry no general voting rights, are convertible into common shares at 85% of the prior trading day’s closing price, subject to a floor price, and were sold in a private placement under Regulation D, with iSpecimen granting investors registration rights for the resale of conversion shares and appointing E.F. Hutton & Co. as exclusive placement agent, a move that strengthens the company’s capital position but introduces potential future equity dilution for existing shareholders.

The most recent analyst rating on (ISPC) stock is a Sell with a $0.28 price target. To see the full list of analyst forecasts on iSpecimen stock, see the ISPC Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
iSpecimen Regains Nasdaq Compliance as of November 2025
Positive
Dec 1, 2025

On November 28, 2025, iSpecimen Inc. received confirmation from the Nasdaq Listing Qualifications Staff that it now meets the continued listing requirements under Nasdaq Listing Rules. Previously, on June 4, 2025, the company was notified of non-compliance with the minimum stockholders’ equity, market value of listed securities, or net income requirements. However, as of September 30, 2025, iSpecimen reported stockholders’ equity of $3,072,711, regaining compliance and closing the matter.

The most recent analyst rating on (ISPC) stock is a Sell with a $0.40 price target. To see the full list of analyst forecasts on iSpecimen stock, see the ISPC Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
iSpecimen Faces Nasdaq Delisting Notice for Stock Price
Negative
Nov 21, 2025

On November 19, 2025, iSpecimen Inc. received a notice from Nasdaq indicating that its common stock had fallen below the minimum bid price requirement of $1.00 per share for 30 consecutive business days, putting the company out of compliance with Nasdaq’s listing rules. The company has until May 18, 2026, to regain compliance by achieving a closing bid price of at least $1.00 per share for ten consecutive business days. If compliance is not regained, iSpecimen may seek an additional compliance period or face potential delisting, with options including a reverse stock split to address the deficiency.

The most recent analyst rating on (ISPC) stock is a Sell with a $0.50 price target. To see the full list of analyst forecasts on iSpecimen stock, see the ISPC Stock Forecast page.

Executive/Board Changes
iSpecimen Appoints Katharyn Field as New CEO
Neutral
Nov 7, 2025

On November 7, 2025, iSpecimen Inc. announced significant leadership changes with the appointment of Ms. Katharyn Field as Chief Executive Officer, Secretary, and Treasurer, succeeding Mr. Robert Bradley Lim who resigned from these roles and the Board. Ms. Field, who has been serving as President since February 2025, brings extensive experience in strategy consulting and executive leadership, particularly in the cannabis industry. Additionally, Mr. Arphing (Tommy) Lee was appointed as an independent director, joining the Audit and Nominating and Corporate Governance Committees. The company emphasized that these leadership changes are not expected to disrupt operations, and the Board remains focused on executing the company’s objectives.

The most recent analyst rating on (ISPC) stock is a Hold with a $1.00 price target. To see the full list of analyst forecasts on iSpecimen stock, see the ISPC Stock Forecast page.

Private Placements and FinancingRegulatory Filings and ComplianceShareholder MeetingsStock Split
iSpecimen Approves Key Proposals in Stockholder Meeting
Positive
Nov 3, 2025

On October 30, 2025, iSpecimen Inc. held a special meeting of stockholders to vote on several key proposals. The company successfully approved a reverse stock split, an increase in authorized shares, and amendments related to private financing transactions and convertible securities, all of which are aimed at enhancing its financial flexibility and compliance with Nasdaq rules.

The most recent analyst rating on (ISPC) stock is a Hold with a $1.00 price target. To see the full list of analyst forecasts on iSpecimen stock, see the ISPC Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 14, 2026