Solid Full-Year Financial Performance
Revenue of $17.3B, up 5% year-over-year; EBITDA of $5.3B, up 12%; EPS up 19% to $2.93; free cash flow up 16% to $2.4B. Net debt/EBITDA improved to 2.5x (target 2.0x by 2027).
Innovative Portfolio Driving Growth
Combined innovative brands (AUSTEDO, UZEDY, AJOVY) reached $3.1B for the year, up ~35%, and exceeded $1B in Q4. Management highlights this portfolio as the primary growth driver and margin transformer.
AUSTEDO: Strong Underlying Momentum
AUSTEDO full year ~$2.2B, up 34%; Q4 $725M, up 40%. TRx +10% and milligram volume +19%; AUSTEDO XR accounts for 60% of new patients. 2026 guidance of $2.4B–$2.55B (potential to hit $2.5B earlier than expected).
UZEDY: Rapid Adoption
UZEDY full year $191M, up 63%; Q4 $55M, up 28%. TRx volume grew 123% YoY and guidance set at $250M–$280M for 2026, indicating fast expansion of the long-acting injectable market.
AJOVY Continues Strong Performance
AJOVY full year $673M, up 30%; Q4 $211M, up 43%. Maintains leading positions in key U.S. headache centers and international markets with 2026 guidance of $750M–$790M.
Pipeline Advancement and Near-Term Catalysts
Multiple R&D milestones in 2026: olanzapine LAI EU filing and anticipated approval by year-end, DARI Phase III enrollment completed (including pediatrics), duvakitug maintenance data due H1, anti-IL-15 (vitiligo) funding from Royalty Pharma and Phase Ib readouts — management expects seven milestones in 2026.
Transformation Program Progress
Transformation target of ~$700M net savings by 2027; achieved $70M in 2025 and on track to realize ~2/3 of savings by end-2026. Savings expected to support margin expansion toward a 30% non-GAAP operating margin target.
Biosimilars Portfolio Build
10 biosimilar assets in market today, 6 additional launches planned through 2027 and ~10 more from 2028+, targeting ~$400M of biosimilars growth by 2027 and positioning Teva as one of the largest biosimilar portfolios.