IDEAYA Biosciences: Promising Future with Innovative Dual KAT6/7 Inhibitor and Strong Financial Positions: IDYA this morning announced IND submission for IDE574, a differenated and potenal first-in-class dual KAT6/7 inhibitor, with plans to iniate monotherapy dose escalaon in 1Q 2026, share preclinical data at a 1H 2026 medical conference, and develop the asset primarily in HR+ breast and lung cancers. Recall that IDYA has previously & recently noted that the broader mechanism of dual KAT6/7 inhibion, relave to KAT6 alone (e.g., PFE, OLMA has a clinical-stage asset [LINK], PRLD has an IND-stage KAT6A degrader), should be able to enhance efficacy and possibly drive monotherapy acvity without combining with fulvestrant (parcularly as seen in preclinical data; see 10-Year R&D Day Slides 73-75).