Fractyl Health has demonstrated significant progress in strategic focus and financial strengthening, alongside positive clinical outcomes for Revita. However, increased net loss and R&D expenses pose financial challenges.

Company Guidance -

Q3 2025

During Fractyl Health's Second Quarter 2025 Financial Results and Business Updates Call, the company provided guidance on several key metrics and strategic initiatives. They reported a $23 million underwritten public offering, which has strengthened their financial position and extended their cash runway through critical REMAIN-1 midpoint cohort milestones. The company reduced its burn rate from $25.4 million in Q1 to $19.8 million in Q2, showcasing disciplined cash management. Revenue was not explicitly mentioned, but R&D expenses increased to $21.2 million from $16.8 million in Q2 2024, reflecting the advancement of their REMAIN-1 clinical study and the Rejuva program. SG&A expenses decreased to $4.9 million from $6.2 million in the previous year due to lower stock-based compensation. The net loss for the quarter was $27.9 million compared to $17.2 million in Q2 2024. Fractyl's strategic focus is on addressing weight regain after GLP-1 discontinuation, and they anticipate significant milestones ahead, including a 3-month randomized data readout in September 2025 and 6-month data in Q1 2026. The Revita therapy is positioned as a potential solution for sustained weight maintenance and metabolic benefits, with ongoing efforts to establish a commercial scale, including a collaboration with Bariendo.

Strengthened Financial Position

Fractyl Health strengthened its financial position through a $23 million underwritten public offering of common stock, led by leading healthcare investors. This financing positions the company to capture the value of its clinical and strategic progress.

Reduction in Burn Rate

The company reduced its burn rate from $25.4 million in Q1 to $19.8 million in Q2 by winding down spend on noncritical programs.

Revita's Long-Term Efficacy

Revita showed up to two years of benefit in weight maintenance and blood sugar control in a German real-world registry study, with even greater improvements in body weight at two years than at one year.

REVEAL-1 Positive Data

In June, Fractyl shared positive 3-month open-label data from the REVEAL-1 cohort, where patients demonstrated weight stability after stopping tirzepatide, with nearly half losing more weight post-drug.

Fractyl Health, Inc. (GUTS) Earnings, Revenues Date & History

The upcoming earnings date is based on a company’s previous reporting, and may be updated when the actual date is announced

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GUTS Earnings History

Report Date	Fiscal Quarter	Forecast / EPS	Last Year's EPS	EPS YoY Change	Slides	Play Transcript
Nov 18, 2025	2025 (Q3)	-0.33 / -	-0.43	―	―	―
Aug 12, 2025	2025 (Q2)	-0.36 / -0.55	-0.28	-95.36% (-0.27)	―
May 13, 2025	2025 (Q1)	-0.48 / -0.47	0	―	―
Mar 03, 2025	2024 (Q4)	-0.43 / -0.52	-11.18	95.35% (+10.66)	―
Nov 12, 2024	2024 (Q3)	-0.50 / -0.43	-0.62	30.65% (+0.19)	―
Aug 14, 2024	2024 (Q2)	-0.46 / -0.28	―	―	―
May 13, 2024	2024 (Q1)	- / -	-0.338	―	―
Apr 01, 2024	2023 (Q4)	-0.30 / 0.00	-0.338	―	―	―

The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.

Beat

Missed

GUTS Earnings-Related Price Changes

Report Date	Price 1 Day Before	Price 1 Day After	Percentage Change
Aug 12, 2025	$0.98	$1.01	+3.06%
May 13, 2025	$1.77	$1.54	-12.99%
Mar 03, 2025	$1.56	$1.50	-3.85%
Nov 12, 2024	$2.43	$2.37	-2.47%

Earnings announcements can affect a stock’s price. This table shows the stock's price the day before and the day after recent earnings reports, including the percentage change.

FAQ

When does Fractyl Health, Inc. (GUTS) report earnings?

Fractyl Health, Inc. (GUTS) is schdueled to report earning on Nov 18, 2025, Before Open (Confirmed).

What is Fractyl Health, Inc. (GUTS) earnings time?

Fractyl Health, Inc. (GUTS) earnings time is at Nov 18, 2025, Before Open (Confirmed).

Where can I see when companies are reporting earnings?

You can see which companies are reporting today on our designated earnings calendar.

What companies are reporting earnings today?

You can see a list of the companies which are reporting today on TipRanks earnings calendar.

What is GUTS EPS forecast?

GUTS EPS forecast for the fiscal quarter 2025 (Q3) is -0.33.

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