Quarterly Sales Growth
Total sales up 5% to more than GBP 7.6 billion in Q1 FY2026.
Specialty Medicines Growth
Specialty Medicines up 14%, a major driver of top-line growth.
Shingrix Performance
Shingrix delivered record quarterly sales of >GBP 1 billion, up 20% year‑on‑year; Europe growth +51% and U.S. growth +12%.
Profitability and EPS
Core operating profit grew 10% and EPS grew 9%, supported by favorable product mix and legal settlements.
Strong Cash Generation and Balance Sheet
Cash generation reported at GBP 1.4 billion; net debt at 1.4x EBITDA; free cash flow boosted by a $250 million special ViiV dividend and on‑track share buyback.
HIV Portfolio Momentum
HIV sales grew 10% in Q1; U.S. HIV sales +15%; Cabenuva grew 31%; Apretude grew 44%; 79% accelerated switches from competitor products in the U.S.
Nucala COPD Launch and Market Share
Nucala delivered double‑digit growth following U.S. COPD expansion; new patient starts +65% YoY and ~45% COPD market share in the U.S.; early China uptake ~50% of new COPD patients.
Oncology Successes (Jemperli, Mo‑Rez, Ris‑Rez)
Jemperli sales GBP 232 million, up 40% with RUBY 4‑year follow‑up showing 66% reduction in risk of death for dMMR MSI‑high endometrial cancer; Mo‑Rez Phase I highest‑dose confirmed ORR 62% (PROC) and 67% (advanced EC); Hansoh data for Ris‑Rez combo showed 47% ORR and median PFS 14 months.
Bepirovirsen Phase III Results and Regulatory Progress
Positive Phase III bepirovirsen data for functional cure in chronic hepatitis B; FDA breakthrough designation and PDUFA date set for 26 October; priority review accepted in China.
R&D and BD Acceleration
Multiple late‑stage program starts (7 Phase III in 2025; 10 more starting in 2026), acquisitions (35Pharma HS235 closed Apr 15; RAPT Therapeutics GBP 1.4bn upfront referenced), and plans for multiple pivotal trials (e.g., Ris‑Rez, Mo‑Rez, velzatinib).