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Gri Bio, Inc. (GRI)
NASDAQ:GRI
US Market

GRI Bio (GRI) AI Stock Analysis

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GRI

GRI Bio

(NASDAQ:GRI)

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Neutral 43 (OpenAI - 5.2)
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Neutral 43 (OpenAI - 5.2)
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Neutral 43 (OpenAI - 5.2)
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Neutral 43 (OpenAI - 5.2)
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Neutral 43 (OpenAI - 5.2)
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Neutral 43 (OpenAI - 5.2)
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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$2.50
▲(792.86% Upside)
Action:ReiteratedDate:03/18/26
The score is held down primarily by weak financial performance (widening losses, negative margins, and elevated cash burn) and bearish technicals (below key moving averages with negative MACD). A low-debt balance sheet and encouraging Phase 2a updates provide partial offsets, but the negative P/E and lack of dividend support keep the overall profile risk-tilted.
Positive Factors
Clinical proof-of-concept
Robust Phase 2a molecular and biomarker signals that align with functional endpoints indicate real disease‑modifying potential for GRI-0621. Durable clinical differentiation increases likelihood of partnerships, follow-on funding, and higher commercial value if later‑stage trials confirm efficacy and safety.
Low leverage
Extremely low debt and improved equity reduce bankruptcy and interest‑rate vulnerability, giving management structural flexibility to fund R&D or negotiate collaborations. A conservative capital structure lowers solvency risk over the next several quarters while clinical programs advance.
Expanded equity access
A materially enlarged at-the-market facility and contractual waivers provide a durable mechanism to tap public markets incrementally. This funding optionality reduces single‑event financing risk, enabling staged financing of clinical programs and preserving operational continuity over months.
Negative Factors
High cash burn
Sustained negative operating and free cash flow of ~-$10M TTM creates an ongoing funding requirement that shortens runway absent positive trial readouts or new financing. Over 2–6 months this pressure raises dilution risk and constrains investment in parallel programs or scale-up.
Widening losses
Deep and expanding operating losses mean the business cannot self-finance growth or R&D, weakening return metrics and making strategic partnerships harder to structure on favorable terms. Persistent negative margins erode equity and increase reliance on dilutive capital over time.
Listing/compliance fragility
A recent reverse split and conditional Nasdaq compliance highlight a fragile equity base and recurring listing risk. This structural weakens investor confidence, can limit institutional participation, and makes the company more likely to pursue dilutive financings or strategic concessions to maintain listing and operations.

GRI Bio (GRI) vs. SPDR S&P 500 ETF (SPY)

GRI Bio Business Overview & Revenue Model

Company DescriptionGRI Bio, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, developing, and commercializing therapies that target diseases leading to inflammatory, fibrotic, and autoimmune disorders in the United States. Its lead product candidate is GRI-0621, an oral inhibitor of type 1 Natural Killer T cells, which is in phase IIa clinical trial for the treatment of severe fibrotic lung diseases, such as idiopathic pulmonary fibrosis. The company's portfolio also includes GRI-0803, a novel oral agonist of type 2 Natural Killer T cells that is in preclinical development for the treatment of autoimmune disorders; a proprietary library of 500+ compounds; and GRI-0124 and GRI-0729 for balance inflammatory immune responses. GRI Bio, Inc. was formerly known as Glycoregimmune, Inc. GRI Bio, Inc. was founded in 2009 and is based in LA Jolla, California.
How the Company Makes Moneynull

GRI Bio Financial Statement Overview

Summary
Weak operating performance and cash burn drive the score: TTM revenue is $28.9M but gross profit is slightly negative, net margin is about -41%, and losses widened versus 2024. Cash flow is also pressured with TTM operating cash flow/free cash flow around -$10.2M. Offsetting this somewhat is a conservative balance sheet with minimal debt (~$71K) and improved equity (~$6.0M).
Income Statement
18
Very Negative
TTM (Trailing-Twelve-Months) revenue is $28.9M, but profitability remains very weak: gross profit is slightly negative and operating results are deeply loss-making (about a 41% net loss margin). Losses have widened versus 2024 (net loss of ~$12.0M TTM vs. ~$8.2M in 2024), indicating higher cost structure and limited operating leverage. Strength: revenue is present in the latest period; weakness: persistent and expanding losses with negative margins across the income statement.
Balance Sheet
62
Positive
Leverage looks very conservative with minimal debt (TTM total debt ~$71K) and a very low debt-to-equity ratio (~0.01), which reduces financial risk. Equity has improved meaningfully versus earlier years (moving from negative equity in 2021–2022 to ~$6.0M in TTM), supporting balance-sheet stability. The key weakness is returns: equity is not earning a profit (TTM return on equity is strongly negative), consistent with ongoing losses.
Cash Flow
24
Negative
Cash generation is a major pressure point: TTM operating cash flow and free cash flow are both around -$10.2M, reflecting continued cash burn to fund operations. Cash burn has increased versus 2024 (about -$8.6M), which raises funding risk if losses persist. A modest positive is that free cash flow tracks net income closely (both negative), suggesting cash losses are not being masked by large non-cash adjustments—but the overall cash profile remains weak.
BreakdownTTMDec 2025Dec 2024Mar 2024Dec 2022Dec 2021
Income Statement
Total Revenue28.87M0.0022.54M0.000.000.00
Gross Profit-4.00K-4.00K-4.00K-57.00K-50.00K-73.00K
EBITDA-11.96M-11.97M-8.20M-10.90M-2.51M-9.21M
Net Income-11.96M-11.96M-8.21M-13.04M-3.22M-9.30M
Balance Sheet
Total Assets8.67M8.67M5.74M2.96M383.00K218.00K
Cash, Cash Equivalents and Short-Term Investments8.23M8.23M5.03M1.81M9.00K90.00K
Total Debt71.00K71.00K119.00K14.00K673.00K3.61M
Total Liabilities2.66M2.66M1.71M2.70M2.01M4.94M
Stockholders Equity6.01M6.01M4.03M259.00K-1.63M-4.72M
Cash Flow
Free Cash Flow-10.19M-10.19M-8.61M-9.00M-1.09M-847.00K
Operating Cash Flow-10.19M-10.19M-8.61M-8.99M-1.08M-847.00K
Investing Cash Flow-3.00K-3.00K0.00-8.00K-3.00K0.00
Financing Cash Flow13.39M13.39M11.83M10.80M1.01M600.00K

GRI Bio Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.28
Price Trends
50DMA
3.67
Negative
100DMA
20.24
Negative
200DMA
33.21
Negative
Market Momentum
MACD
-0.49
Negative
RSI
37.14
Neutral
STOCH
42.48
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GRI, the sentiment is Negative. The current price of 0.28 is below the 20-day moving average (MA) of 2.55, below the 50-day MA of 3.67, and below the 200-day MA of 33.21, indicating a neutral trend. The MACD of -0.49 indicates Negative momentum. The RSI at 37.14 is Neutral, neither overbought nor oversold. The STOCH value of 42.48 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GRI.

GRI Bio Risk Analysis

GRI Bio disclosed 54 risk factors in its most recent earnings report. GRI Bio reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

GRI Bio Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
43
Neutral
$3.41M-381.74%98.22%
43
Neutral
$2.39M-82.17%-3.27%51.83%
33
Underperform
$1.73M-0.10-263.57%-34.58%96.41%
29
Underperform
$3.26M-168.95%90.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GRI
GRI Bio
2.36
-229.20
-98.98%
OGEN
Oragenics
0.75
-7.05
-90.43%
INM
InMed Pharmaceuticals
0.82
-1.96
-70.61%
KTTA
Pasithea Therapeutics Corp
0.80
-0.44
-35.73%
ONCO
Onconetix
0.62
-10.26
-94.30%

GRI Bio Corporate Events

Business Operations and StrategyPrivate Placements and Financing
GRI Bio Expands At-The-Market Equity Offering Capacity
Neutral
Jan 30, 2026

GRI Bio, Inc. amended its existing at-the-market equity offering program with H.C. Wainwright & Co., LLC on January 29, 2026, effective January 28, 2026, significantly increasing the potential size of the offering. The company raised the aggregate cap on common stock issuable under the program from $10 million to up to $60 million, subject to the amount registered on its prospectus supplement, and obtained waivers of certain provisions in a December 11, 2025 securities purchase agreement to permit these issuances, expanding its flexibility to raise capital through ongoing share sales.

The most recent analyst rating on (GRI) stock is a Sell with a $4.00 price target. To see the full list of analyst forecasts on GRI Bio stock, see the GRI Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
GRI Bio reports promising Phase 2a data in IPF
Positive
Jan 28, 2026

On January 28, 2026, GRI Bio reported additional positive data from its recently completed Phase 2a clinical trial of GRI-0621 in idiopathic pulmonary fibrosis, showing that RNA-sequencing gene expression analysis revealed significant modulation of genes linked to lung injury, myofibroblast activation, extracellular matrix deposition, fibrosis progression, and alveolar repair compared with placebo. The new molecular findings align with earlier biomarker and functional data indicating reduced neutrophil activity, lower pro-fibrotic cytokine levels, increased collagen degradation, and signals consistent with lung repair and regeneration, suggesting that GRI-0621 may act as a disease-modifying therapy that supports true lung tissue regeneration rather than merely slowing decline; these effects were observed alongside a favorable safety profile and secondary endpoint signals, including a higher proportion of patients with no decline in forced vital capacity at 12 weeks versus standard of care, underscoring the candidate’s potential differentiation within the IPF treatment landscape.

The most recent analyst rating on (GRI) stock is a Sell with a $0.22 price target. To see the full list of analyst forecasts on GRI Bio stock, see the GRI Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and ComplianceShareholder MeetingsStock Split
GRI Bio Announces 1-for-28 Reverse Stock Split
Negative
Jan 21, 2026

On January 21, 2026, GRI Bio, Inc. announced that its board and stockholders had approved a 1-for-28 reverse stock split of its common stock, following a special meeting held on January 15, 2026. The reverse split will take legal effect at 4:01 p.m. Eastern Time on January 23, 2026, with the stock expected to begin trading on a split-adjusted basis on the Nasdaq Capital Market under the existing ticker “GRI” and a new CUSIP number on January 26, 2026. The move will reduce the number of outstanding common shares from approximately 15.0 million to about 536,000 without changing the total authorized share count, and will include proportional adjustments to outstanding options, warrants, convertible securities and equity incentive plans, while cash will be paid in lieu of fractional shares. The company stated that the reverse split is intended to increase its per-share trading price and help it regain compliance with Nasdaq’s minimum bid price requirement, a step that could prove pivotal for maintaining its listing and access to public capital markets, with operational mechanics arranged so that most shareholders will not need to take any action as positions are automatically adjusted by brokers and the transfer agent.

The most recent analyst rating on (GRI) stock is a Hold with a $0.21 price target. To see the full list of analyst forecasts on GRI Bio stock, see the GRI Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
GRI Bio Regains Conditional Compliance With Nasdaq Listing Requirements
Neutral
Jan 16, 2026

On January 15, 2026, GRI Bio, Inc. was notified by Nasdaq’s Listing Qualifications Staff that it had conditionally regained compliance with Nasdaq Listing Rule 5550(b)(1), which requires companies with a market value under $35 million and annual net income under $500,000 to maintain at least $2.5 million in stockholders’ equity. The company had previously been found out of compliance based on its Form 10-Q for the quarter ended September 30, 2025, and while the current determination averts an immediate delisting, GRI Bio’s stock remains at risk of future delisting if it fails to maintain the required equity levels in subsequent filings.

The most recent analyst rating on (GRI) stock is a Hold with a $0.23 price target. To see the full list of analyst forecasts on GRI Bio stock, see the GRI Stock Forecast page.

Delistings and Listing ChangesPrivate Placements and FinancingRegulatory Filings and ComplianceShareholder MeetingsStock Split
GRI Bio Shareholders Authorize Reverse Stock Split Plan
Neutral
Jan 15, 2026

On January 15, 2026, GRI Bio, Inc. held a virtual special meeting of stockholders at which shareholders approved an amendment to the company’s certificate of incorporation authorizing a reverse stock split of its common stock at a ratio between 1-for-2 and 1-for-30, with the final ratio and implementation left to the discretion of the board, and also approved the potential adjournment or postponement of the meeting if additional proxies were needed. The corporate actions followed a November 26, 2025 notice from Nasdaq that GRI Bio was not in compliance with the minimum stockholders’ equity requirement for continued listing, and the company’s subsequent completion on December 12, 2025 of an approximately $8 million best-efforts public offering of common stock and warrants, after which GRI Bio believes its stockholders’ equity exceeded the required $2.5 million threshold, though Nasdaq will continue to monitor compliance and the company could still face delisting risk if it falls short in future reporting periods.

The most recent analyst rating on (GRI) stock is a Hold with a $0.23 price target. To see the full list of analyst forecasts on GRI Bio stock, see the GRI Stock Forecast page.

Private Placements and FinancingRegulatory Filings and Compliance
GRI Bio Expands At-The-Market Equity Offering Capacity
Neutral
Jan 9, 2026

On January 9, 2026, GRI Bio, Inc. filed a prospectus supplement to increase the maximum amount of common stock it may issue under its at-the-market offering agreement with H.C. Wainwright & Co. to an aggregate of $7.38 million in new shares, on top of approximately $6.17 million of stock already sold under the program. The company also obtained a waiver of certain provisions in a December 11, 2025 securities purchase agreement to allow further issuances under this at-the-market facility, and its counsel Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. issued a legal opinion confirming that shares sold pursuant to the program will be validly issued, fully paid and nonassessable, underscoring GRI Bio’s continued reliance on equity issuance as a funding mechanism and clarifying the legal framework for investors participating in these offerings.

The most recent analyst rating on (GRI) stock is a Hold with a $0.29 price target. To see the full list of analyst forecasts on GRI Bio stock, see the GRI Stock Forecast page.

Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
GRI Bio Highlights Positive Phase 2a Data in IPF
Positive
Jan 8, 2026

On January 8, 2026, GRI Bio reported additional positive immune profiling data from its Phase 2a clinical trial of GRI-0621 in idiopathic pulmonary fibrosis, showing inhibition of invariant NKT cells and a shift toward an anti-fibrotic immune profile, with increased interferon-gamma and reduced pro-fibrotic cytokines including IL-4, IL-13, IL-17A, IL-22 and TGF-β across multiple immune cell types in lung and blood samples. These mechanistic findings, which align with previously disclosed safety, tolerability and lung function benefits and suggest disease-modifying activity and fibrosis reversal, bolster clinical proof-of-concept for GRI-0621 and support its differentiation from existing IPF therapies; separately, the company noted that its December 2025 public offering has lifted stockholders’ equity above Nasdaq’s $2.5 million minimum, helping to stabilize its listing compliance position.

The most recent analyst rating on (GRI) stock is a Hold with a $0.24 price target. To see the full list of analyst forecasts on GRI Bio stock, see the GRI Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 18, 2026