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ValiRx PLC (GB:VAL)
LSE:VAL

ValiRx plc (VAL) AI Stock Analysis

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GB:VAL

ValiRx plc

(LSE:VAL)

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Neutral 41 (OpenAI - 5.2)
Rating:41Neutral
Price Target:
0.40p
▲(0.25% Upside)
ValiRx plc's overall stock score is primarily impacted by its challenging financial performance, characterized by significant losses and reliance on external financing. The technical analysis suggests a bearish trend, with some potential for upward movement. The valuation is unattractive due to a negative P/E ratio and lack of dividend yield.
Positive Factors
Proprietary technology platform
ValiRx's proprietary technology platforms provide a durable competitive advantage: IP and differentiated therapeutics can create barriers to entry, support long-term licensing or partnership opportunities, and increase the probability of sustained clinical and commercial value creation.
High equity ratio / solid balance sheet position
A relatively high equity ratio gives ValiRx a structural buffer against volatility common in biotech. This stronger equity base reduces near-term solvency risk, supports continued R&D investment over months, and provides financial flexibility compared with highly leveraged peers.
Low leverage
Minimal leverage lowers fixed interest burdens and reduces default risk, preserving cash for clinical development. Over a multi-month horizon, low debt gives management optionality to pursue partnerships or staged financing without immediate heavy servicing constraints.
Negative Factors
Negative profitability and margins
Persistently negative gross and net margins reflect structural issues: cost of revenue exceeds sales and operations produce losses. Without durable margin improvement or scale, the company cannot self-fund development, making long-term viability contingent on external capital or profitable partnerships.
Negative free cash flow and financing reliance
Ongoing negative free cash flow and dependence on financing are structural weaknesses. Over several months this increases dilution and execution risk, constrains strategic choices, and elevates vulnerability to capital market access or higher financing costs, affecting sustainability of R&D programs.
Ongoing net losses and reliance on external financing
Chronic net losses paired with frequent external financing indicate the company cannot yet generate self-sustaining cash returns. This creates long-term execution risk, potential equity dilution, and pressure to secure partnerships or milestone payments to fund clinical progress and operations.

ValiRx plc (VAL) vs. iShares MSCI United Kingdom ETF (EWC)

ValiRx plc Business Overview & Revenue Model

Company DescriptionValiRx plc, a biopharmaceutical company, engages in the development of oncology therapeutics and companion diagnostics in the United Kingdom. The company's lead drug candidates include VAL201, a small molecule that has completed Phase I/II trials for the treatment of prostate cancer and other hormone associated solid tumours comprising breast and ovarian cancer; and VAL401, a reformulation of anti-psychotic drug risperidone, which has completed Phase II clinical trial for the treatment of non-small cell lung cancer. Its drug candidates also comprise VAL301, a peptide ingredient that in pre-clinical development for the treatment of women with endometriosis; and BC201, a combination of the peptide ingredient of VAL201/VAL301 with complementary active components for the treatment for patients suffering severe symptoms of Covid-19. ValiRx plc was incorporated in 2000 and is based in Hatfield, the United Kingdom.
How the Company Makes MoneyValiRx generates revenue primarily through the development and commercialization of its therapeutic candidates. The company's revenue model includes potential licensing agreements, partnerships with larger pharmaceutical companies, and grants for research and development. Key revenue streams may arise from milestone payments as products progress through clinical trials and achieve regulatory approvals, as well as royalties from sales of successfully commercialized drugs. Additionally, ValiRx may benefit from collaborations with academic institutions and other biotech firms that can provide funding and resources for its research initiatives.

ValiRx plc Financial Statement Overview

Summary
ValiRx plc is facing substantial financial challenges typical of a biotech firm in its growth phase, with ongoing net losses and reliance on external financing. While equity is strong, profitability and cash flow constraints pose significant risks. The company needs to improve operational efficiency and revenue generation to enhance financial stability and investor confidence.
Income Statement
ValiRx plc exhibits a challenging income statement with negative profitability margins. The gross profit margin is negative due to the cost of revenue exceeding total revenue, and the net profit margin is significantly negative, indicating substantial losses relative to revenue. Revenue growth is present, but the base is very low, which makes the growth percentage less impactful. EBIT and EBITDA margins are also negative, reflecting operational inefficiencies and high operating expenses.
Balance Sheet
The balance sheet shows a relatively solid equity position compared to liabilities, with a high equity ratio. However, the debt-to-equity ratio is low, indicating minimal leverage, which can be a double-edged sword in biotech if additional funding is needed. Return on equity is negative, driven by continuous net losses, signaling the need for improved profitability to enhance shareholder value.
Cash Flow
Cash flow statements reveal negative free cash flow, though there is a slight improvement in operating cash flow. The company relies heavily on financing activities for cash, which may not be sustainable long-term. The operating cash flow to net income ratio is negative, suggesting cash flow challenges in converting sales into cash. Free cash flow growth rates are negative, reflecting ongoing capital expenditure needs without sufficient revenue support.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue49.77K9.60K0.000.000.00
Gross Profit-217.22K-246.04K-224.27K-228.79K-229.50K
EBITDA-1.86M-2.04M-2.37M-1.45M-1.31M
Net Income-1.92M-2.04M-2.41M-1.55M-1.47M
Balance Sheet
Total Assets4.26M3.13M3.98M3.52M4.94M
Cash, Cash Equivalents and Short-Term Investments1.56M174.68K1.14M593.67K1.85M
Total Debt11.86K22.07K37.71K58.72K71.06K
Total Liabilities346.41K226.51K149.65K109.56K182.40K
Stockholders Equity4.32M3.22M4.05M3.60M4.91M
Cash Flow
Free Cash Flow-1.62M-2.08M-1.71M-1.26M-2.00M
Operating Cash Flow-1.58M-1.77M-1.71M-1.26M-1.91M
Investing Cash Flow-38.16K-306.18K0.000.00-91.29K
Financing Cash Flow3.00M1.12M2.26M7.34K3.85M

ValiRx plc Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.40
Price Trends
50DMA
0.32
Positive
100DMA
0.46
Negative
200DMA
0.50
Negative
Market Momentum
MACD
0.02
Negative
RSI
54.75
Neutral
STOCH
54.17
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:VAL, the sentiment is Neutral. The current price of 0.4 is above the 20-day moving average (MA) of 0.37, above the 50-day MA of 0.32, and below the 200-day MA of 0.50, indicating a neutral trend. The MACD of 0.02 indicates Negative momentum. The RSI at 54.75 is Neutral, neither overbought nor oversold. The STOCH value of 54.17 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GB:VAL.

ValiRx plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
£116.75M-8.52-94.12%
47
Neutral
£27.61M-5.93-202.14%23.76%
46
Neutral
£36.70M-8.20-259.88%
45
Neutral
£4.51M-1.62-53.79%85.56%
43
Neutral
£37.52M-2.80-609.30%
41
Neutral
£2.90M-0.27418.49%27.86%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:VAL
ValiRx plc
0.39
-0.29
-42.22%
GB:TCF
Evgen Pharma
0.21
-0.54
-72.00%
GB:IMM
ImmuPharma
7.30
3.75
105.63%
GB:SAR
Sareum Holdings
20.00
-2.50
-11.11%
GB:SCLP
Scancell Holdings
11.25
1.15
11.39%
GB:HEMO
HemoGenyx Pharmaceuticals Plc
621.00
228.50
58.22%

ValiRx plc Corporate Events

Private Placements and FinancingShareholder Meetings
ValiRx Advances with New Equity and Warrant Issuance Post-General Meeting
Positive
Nov 20, 2025

ValiRx plc announced the successful passing of all resolutions at its recent General Meeting, paving the way for the issuance of new equity and warrants as part of its fundraising efforts. The company plans to admit 256,067,800 new shares to trading on AIM, with the issuance of 368,372,400 fundraising warrants and 16,036,120 broker warrants, which are exercisable until the third anniversary of the admission. This strategic move is expected to bolster ValiRx’s financial position, enabling further investment in its pipeline of cancer therapeutics and women’s health products, potentially enhancing its market position and delivering value to stakeholders.

The most recent analyst rating on (GB:VAL) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on ValiRx plc stock, see the GB:VAL Stock Forecast page.

Business Operations and StrategyPrivate Placements and FinancingShareholder Meetings
ValiRx PLC Announces Fundraising to Boost Cancer and Women’s Health Research
Positive
Nov 4, 2025

ValiRx PLC has announced the posting of a circular and notice for a General Meeting to discuss a fundraising initiative aimed at raising approximately £902,000. The funds will support research and development efforts, including the preclinical development of Cytolytix and VAL201 2.0, as well as operational costs. This fundraising effort is part of ValiRx’s strategy to enhance the translation of novel research into clinical applications, focusing on oncology and women’s health. The issuance of new shares and warrants will significantly increase the company’s share capital, impacting its market positioning and providing resources for future growth.

The most recent analyst rating on (GB:VAL) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on ValiRx plc stock, see the GB:VAL Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
ValiRx PLC Raises £902,000 Through Successful Fundraising
Positive
Nov 4, 2025

ValiRx PLC has successfully raised approximately £902,000 through its WRAP Retail Offer and other fundraising activities, issuing new ordinary shares at a price of 0.25 pence per share. This capital injection is expected to support the company’s ongoing operations and strategic initiatives, potentially strengthening its position in the life sciences industry and providing value to its stakeholders.

The most recent analyst rating on (GB:VAL) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on ValiRx plc stock, see the GB:VAL Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
ValiRx Plc Raises £902,000 Through Successful WRAP Retail Offer
Positive
Nov 4, 2025

ValiRx Plc announced the successful completion of its WRAP Retail Offer, raising approximately £152,000 through the issuance of new ordinary shares. Combined with previous fundraising efforts, the company has secured a total of £902,000. The new shares are expected to commence trading on AIM by 21 November 2025, subject to the approval of Fundraising Resolutions at the General Meeting. This fundraising effort is anticipated to bolster ValiRx’s financial position and support its strategic initiatives in the life sciences sector.

The most recent analyst rating on (GB:VAL) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on ValiRx plc stock, see the GB:VAL Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
ValiRx Plc Launches £300,000 Retail Offer to Boost Cancer Therapeutics Development
Positive
Oct 30, 2025

ValiRx Plc has announced a retail offer via the Winterflood Retail Access Platform to raise up to £300,000 through the issuance of new ordinary shares and warrants. This initiative is part of a broader fundraising effort, where the company has conditionally raised £750,000 through a placing and subscription of new shares. The funds raised will support the company’s ongoing projects and operations. The offer is open to eligible retail investors in the UK and is expected to close on 3 November 2025, with the results announced shortly thereafter. This move aims to strengthen ValiRx’s financial position and expand its retail shareholder base.

The most recent analyst rating on (GB:VAL) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on ValiRx plc stock, see the GB:VAL Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
ValiRx PLC Launches £1.05 Million Fundraising to Boost Cancer and Women’s Health Initiatives
Neutral
Oct 30, 2025

ValiRx PLC has announced a fundraising initiative to raise up to £1,050,000 through a combination of firm and conditional placings, a WRAP Retail Offer, and direct subscriptions by company directors. The initiative, which includes the issuance of new shares and fundraising warrants, aims to support the company’s operations in a challenging funding environment. The funds will be used to expand ValiRx’s evaluation pipeline and progress existing projects, enhancing its strategic position in the oncology and women’s health sectors.

The most recent analyst rating on (GB:VAL) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on ValiRx plc stock, see the GB:VAL Stock Forecast page.

Business Operations and Strategy
ValiRx PLC Advances Cancer Therapeutics with Strategic Partnerships and Innovations
Positive
Oct 14, 2025

ValiRx PLC announced significant progress in its subsidiary Inaphaea Limited, including the completion of a service contract phase with Amply Discovery Limited and a substantial UKRI grant for developing an in-silico spheroid modeling platform. These advancements, alongside collaborations with Nottingham Health Trust and TwinEdge BioScience, enhance ValiRx’s capabilities in drug development and patient-derived cell modeling. Additionally, ValiRx’s agreement with Apis Assay Technologies Ltd to evaluate HER2 targeting technology and recent academic appointments for key personnel underscore the company’s commitment to innovation and collaboration in cancer therapeutics.

The most recent analyst rating on (GB:VAL) stock is a Hold with a £0.50 price target. To see the full list of analyst forecasts on ValiRx plc stock, see the GB:VAL Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 10, 2025