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Shield Therapeutics PLC (GB:STX)
LSE:STX
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Shield Therapeutics (STX) AI Stock Analysis

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GB:STX

Shield Therapeutics

(LSE:STX)

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Neutral 57 (OpenAI - 4o)
Rating:57Neutral
Price Target:
6.50p
▼(-18.75% Downside)
The overall stock score is primarily influenced by the company's robust technical performance, indicating strong market momentum. However, significant financial weaknesses, including negative profitability and cash flow issues, weigh heavily on the score. Valuation concerns due to a negative P/E ratio and lack of dividend yield further impact the stock's attractiveness.
Positive Factors
Revenue Growth
Strong revenue growth demonstrates the company's ability to expand its market presence and increase product adoption, which is crucial for long-term sustainability and competitiveness in the pharmaceutical industry.
Product Focus
A clear focus on iron deficiency treatments positions Shield Therapeutics as a specialist in a niche market, potentially leading to a strong competitive advantage and brand recognition in this therapeutic area.
Cash Flow Management
Improved cash flow management indicates better operational efficiency and financial discipline, which are essential for sustaining business operations and funding future growth initiatives.
Negative Factors
Negative Profitability
Persistent negative profitability poses a significant challenge, as it can hinder the company's ability to reinvest in growth opportunities and may require external financing to sustain operations.
Balance Sheet Weakness
Negative equity indicates financial distress and potential insolvency risk, limiting the company's ability to secure favorable financing terms and invest in strategic initiatives.
High Leverage
High leverage can strain financial resources and increase vulnerability to economic downturns, potentially impacting long-term financial stability and operational flexibility.

Shield Therapeutics (STX) vs. iShares MSCI United Kingdom ETF (EWC)

Shield Therapeutics Business Overview & Revenue Model

Company DescriptionShield Therapeutics plc, a specialty pharmaceutical company, engages in the development and commercialization of clinical stage pharmaceuticals to treat unmet medical needs. The company's lead product is Accrufer/Feraccru, a non-salt based oral therapy for the treatment of iron deficiency with or without anemia in adults. It also develops PT20, a novel iron-based phosphate binder that has completed its Phase II pivotal study for the treatment of hyperphosphatemia in patients with chronic kidney disease. The company was founded in 2008 and is based in Gateshead, the United Kingdom.
How the Company Makes MoneyShield Therapeutics generates revenue primarily through the sale of its lead product, Accrufer, which is marketed to healthcare providers and patients in various markets. The company may also explore licensing agreements and partnerships with other pharmaceutical firms to expand its market reach and enhance distribution channels. Additionally, Shield Therapeutics could benefit from collaborations in clinical trials or research initiatives that lead to new product developments or indications, thereby creating further revenue opportunities. The effectiveness of its marketing strategies and the demand for its products play crucial roles in driving its earnings.

Shield Therapeutics Financial Statement Overview

Summary
Despite strong revenue growth, Shield Therapeutics faces severe financial challenges with negative profitability, cash flow issues, and a strained balance sheet characterized by negative equity and high leverage.
Income Statement
35
Negative
The company has shown significant revenue growth, with total revenue increasing from 1.5 million in 2021 to 25.2 million in 2024, representing a strong growth trajectory. However, the net profit margin remains deeply negative due to substantial net losses, and both EBIT and EBITDA margins are negative, indicating ongoing operational challenges and profitability issues.
Balance Sheet
28
Negative
The balance sheet reflects a negative stockholders' equity as of 2024, indicating financial distress and a potential risk of insolvency. The debt-to-equity ratio is high due to negative equity, and the equity ratio is also negative, highlighting a critical situation in terms of financial stability and leverage.
Cash Flow
40
Negative
Free cash flow remains negative, although there is a small improvement in operating cash flow. The free cash flow to net income ratio is negative, indicating cash flow problems. However, the company has managed to reduce the magnitude of negative operating cash flow compared to previous years, showing a slight improvement in cash management.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue25.18M13.09M4.47M1.52M10.39M
Gross Profit10.57M4.03M2.00M539.00K9.03M
EBITDA-16.58M-30.29M-37.39M-17.35M820.00K
Net Income-21.27M-33.29M-40.44M-19.34M-2.63M
Balance Sheet
Total Assets45.90M48.80M22.07M44.41M32.53M
Cash, Cash Equivalents and Short-Term Investments5.61M13.95M2.82M12.12M2.94M
Total Debt21.06M20.25M6.10M156.00K28.00K
Total Liabilities46.95M33.77M16.65M3.38M2.25M
Stockholders Equity-1.05M11.79M5.43M41.03M30.28M
Cash Flow
Free Cash Flow-7.03M-40.07M-20.14M-18.80M-1.42M
Operating Cash Flow-7.01M-37.13M-18.25M-16.74M-1.40M
Investing Cash Flow-1.89M-2.43M-1.70M-2.05M-20.00K
Financing Cash Flow4.21M49.66M7.71M27.58M-47.00K

Shield Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price8.00
Price Trends
50DMA
5.93
Positive
100DMA
4.25
Positive
200DMA
3.58
Positive
Market Momentum
MACD
0.63
Positive
RSI
57.99
Neutral
STOCH
19.15
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:STX, the sentiment is Positive. The current price of 8 is above the 20-day moving average (MA) of 7.76, above the 50-day MA of 5.93, and above the 200-day MA of 3.58, indicating a bullish trend. The MACD of 0.63 indicates Positive momentum. The RSI at 57.99 is Neutral, neither overbought nor oversold. The STOCH value of 19.15 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GB:STX.

Shield Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
3.56B12.4615.54%3.94%3.73%27.13%
65
Neutral
172.47M32.0128.43%2.00%-0.17%592.46%
57
Neutral
£84.94M-396.71%93.48%51.18%
56
Neutral
395.61M-11.070.00%4.50%74.32%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:STX
Shield Therapeutics
8.00
4.55
131.88%
GB:AGY
Allergy Therapeutics
8.30
3.78
83.63%
GB:ANCR
Animalcare
250.00
11.64
4.88%
GB:HIK
Hikma Pharmaceuticals
1,615.00
-197.70
-10.91%
GB:BXP
Beximco Pharmaceuticals Limited Sponsored GDR RegS
46.50
24.94
115.68%

Shield Therapeutics Corporate Events

Business Operations and StrategyFinancial Disclosures
Shield Therapeutics Doubles ACCRUFeR® Revenues in Q2 2025
Positive
Jul 23, 2025

Shield Therapeutics reported a significant increase in Q2 2025 net revenues for its product ACCRUFeR®, doubling from Q1 to $12.8 million, with a notable rise in prescriptions and average net selling price. The company’s cash reserves were bolstered by milestone payments from international partners, supporting its trajectory towards cash flow positivity by the end of 2025. This robust performance underscores the growing market adoption of ACCRUFeR® and its potential to become the preferred oral iron therapy for patients with iron deficiency, reinforcing Shield’s strategic market positioning.

The most recent analyst rating on (GB:STX) stock is a Hold with a £2.00 price target. To see the full list of analyst forecasts on Shield Therapeutics stock, see the GB:STX Stock Forecast page.

Shareholder MeetingsBusiness Operations and Strategy
Shield Therapeutics Secures Shareholder Support at 2025 AGM
Positive
May 22, 2025

Shield Therapeutics announced the successful passing of all resolutions at its 2025 Annual General Meeting, indicating strong shareholder support. This development underscores the company’s stable governance and may positively impact its strategic initiatives in the competitive pharmaceutical market, particularly in expanding the reach of its flagship product, ACCRUFeR®/FeRACCRU®.

The most recent analyst rating on (GB:STX) stock is a Hold with a £2.00 price target. To see the full list of analyst forecasts on Shield Therapeutics stock, see the GB:STX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2025