The overall stock score for OSE Immunotherapeutics SA is primarily influenced by its financial performance, which shows improvements in profitability and operational efficiency. However, technical analysis indicates bearish momentum, and valuation metrics are weak due to a negative P/E ratio and lack of dividend yield. These factors collectively suggest caution for potential investors.
Positive Factors
Profitability Improvements
The significant improvement in net profit margin indicates enhanced profitability, suggesting that the company is managing costs effectively and improving its bottom line, which is crucial for long-term sustainability.
Operational Efficiency
The improvement in EBIT and EBITDA margins reflects better operational efficiency, indicating that the company is effectively managing its operations to enhance profitability, which is a positive sign for future growth.
Reduced Leverage
The reduction in leverage, as shown by the decreased debt-to-equity ratio, enhances financial stability and reduces risk, providing the company with more flexibility to invest in growth opportunities.
Negative Factors
Declining Revenue
The negative revenue growth rate is a concern as it indicates declining sales, which could impact the company's ability to sustain profitability and growth in the long term.
Negative Cash Flow Growth
Negative free cash flow growth suggests challenges in maintaining cash availability for reinvestment, which could hinder the company's ability to fund future projects and expansions.
Limited Asset Growth
The lack of significant asset growth could limit the company's ability to expand its operations and invest in new opportunities, potentially affecting its competitive position in the market.
OSE Immunotherapeutics SA (OSE) vs. iShares MSCI France ETF (EWQ)
OSE Immunotherapeutics SA Business Overview & Revenue Model
Company DescriptionOSE Immunotherapeutics SA focuses on the development of immunotherapies for immune activation and regulation in the fields of immuno-oncology and autoimmune diseases. Its products include Tedopi that is in Phase III clinical stage for the treatment of non-small cell lung cancer, as well as in Phase II clinical trial to pancreatic and ovarian cancer; CoVepiT, a prophylactic vaccine against the SARS-CoV-2 virus; BI 765063, which is in Phase I clinical trial to treat solid tumors; and BiCKI, a novel bispecific checkpoint inhibitor platform, targeting PD-1 and innovative targets to fight primary and secondary resistance mechanisms developed by cancers. The company's products also comprise OSE-127, a humanized monoclonal antibody that is in Phase II clinical trial for the treatment of ulcerative colitis, as well as Sjögren's Syndrome; FR104, which is in Phase I clinical trial for the treatment of rheumatoid arthritis; and OSE-230, an agonist antibody against ChemR23 to resolve chronic inflammation. OSE Immunotherapeutics SA has collaborations and partnerships with GERCOR, Boehringer Ingelheim, Servier, and Chong Kun Dang Pharmaceutical Corporation. The company was formerly known as OSE Pharma SA and changed its name to OSE Immunotherapeutics SA in May 2016. OSE Immunotherapeutics SA is headquartered in Nantes, France.
How the Company Makes MoneyOSE Immunotherapeutics generates revenue primarily through a combination of product development partnerships, licensing agreements, and potential future sales of its therapeutic candidates. The company collaborates with pharmaceutical companies and research institutions to co-develop its products, often receiving milestone payments as products progress through clinical trials. Additionally, OSE may receive royalties from partners on future sales of any successfully commercialized therapies. The company also seeks funding through grants and public offerings to support its research and development efforts. Significant partnerships with larger pharmaceutical companies enhance its revenue potential and provide financial backing for its innovative projects.
OSE Immunotherapeutics SA Financial Statement Overview
Summary
OSE Immunotherapeutics SA has shown significant improvements in profitability and operational efficiency, with a positive net profit margin and improved EBIT and EBITDA margins. The reduction in leverage and positive return on equity are positive signs for financial stability. However, declining revenue and negative free cash flow growth pose challenges for future growth and sustainability.
Income Statement
65
Positive
The company has shown significant improvement in its income statement metrics over the years. The gross profit margin remains strong at 100%, indicating efficient cost management. The net profit margin has improved dramatically from negative values to 53.6% in the latest year, showcasing a turnaround in profitability. However, the revenue growth rate is negative, indicating a decline in sales, which is a concern for future growth. The EBIT and EBITDA margins have also improved significantly, reflecting better operational efficiency.
Balance Sheet
60
Neutral
The balance sheet shows a mixed picture. The debt-to-equity ratio has decreased from 2.01 to 0.72, indicating reduced leverage and improved financial stability. Return on equity has turned positive at 58.7%, suggesting effective use of equity to generate profits. However, the equity ratio is not explicitly provided, and the company's total assets have not grown significantly, which could limit future expansion.
Cash Flow
55
Neutral
The cash flow statement indicates challenges in maintaining positive cash flow growth. The free cash flow growth rate is negative, reflecting a decline in cash available for reinvestment. However, the operating cash flow to net income ratio is strong at 2.40, indicating good cash generation relative to net income. The free cash flow to net income ratio is nearly 1, suggesting that most of the net income is being converted into free cash flow.
Breakdown
Dec 2024
Dec 2023
Dec 2022
Dec 2021
Dec 2020
Income Statement
Total Revenue
69.88M
2.23M
18.30M
26.31M
10.42M
Gross Profit
69.88M
2.23M
18.30M
26.31M
10.42M
EBITDA
41.20M
-17.50M
-13.11M
-13.72M
-18.24M
Net Income
37.45M
-23.00M
-17.76M
-16.85M
-16.55M
Balance Sheet
Total Assets
123.96M
82.05M
91.67M
101.52M
96.85M
Cash, Cash Equivalents and Short-Term Investments
16.75M
18.67M
25.62M
33.58M
29.37M
Total Debt
46.13M
45.80M
44.79M
37.13M
19.51M
Total Liabilities
60.15M
59.08M
59.12M
53.99M
35.61M
Stockholders Equity
63.81M
22.82M
32.55M
47.89M
61.24M
Cash Flow
Free Cash Flow
48.36M
-20.00M
-18.53M
-10.39M
-19.76M
Operating Cash Flow
48.44M
-19.76M
-18.25M
-9.92M
-19.55M
Investing Cash Flow
-46.91M
-507.00K
26.00K
-827.00K
-504.00K
Financing Cash Flow
-3.46M
13.32M
10.27M
14.96M
23.58M
OSE Immunotherapeutics SA Technical Analysis
Technical Analysis Sentiment
Negative
Last Price5.02
Price Trends
50DMA
5.92
Negative
100DMA
6.00
Negative
200DMA
5.89
Negative
Market Momentum
MACD
-0.19
Positive
RSI
30.55
Neutral
STOCH
13.22
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:OSE, the sentiment is Negative. The current price of 5.02 is below the 20-day moving average (MA) of 5.41, below the 50-day MA of 5.92, and below the 200-day MA of 5.89, indicating a bearish trend. The MACD of -0.19 indicates Positive momentum. The RSI at 30.55 is Neutral, neither overbought nor oversold. The STOCH value of 13.22 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for FR:OSE.
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 07, 2025