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Inventiva SA (FR:IVA)
:IVA
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Inventiva (IVA) AI Stock Analysis

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FR:IVA

Inventiva

(LSE:IVA)

Rating:46Neutral
Price Target:
€2.50
▼(-10.07% Downside)
Inventiva's overall stock score is primarily influenced by its challenging financial performance, characterized by negative equity and cash flow issues. The positive sentiment from the earnings call, highlighting strategic advancements and a robust cash position, provides some balance, though technical indicators and valuation metrics remain weak.
Positive Factors
Drug Approval Progress
Enrollment for the Phase 3 NATIV3 MASH trial is complete with a significant number of patients, indicating progress towards potential drug approval.
Financial Stability
Cash reserves and additional financing provide an operational runway until the third quarter of 2026, ensuring financial stability for ongoing projects.
Regulatory Support
The company has received authorization to implement its pipeline prioritization plan, demonstrating regulatory support for its strategic decisions.
Negative Factors
Financial Performance
IVA reported a FY24 net loss of €184M, highlighting challenges in achieving profitability.
Workforce Reduction
A 50% reduction in workforce and pausing of all preclinical research reflects a strategic shift and potential risks due to narrowed focus.

Inventiva (IVA) vs. iShares MSCI France ETF (EWQ)

Inventiva Business Overview & Revenue Model

Company DescriptionInventiva S.A., a clinical-stage biopharmaceutical company, focuses on the development of oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH), mucopolysaccharidoses (MPS), and other diseases. Its lead product candidate is Lanifibranor, which has completed Phase IIb clinical trial to treat NASH. The company also develops Odiparcil, which has completed Phase IIa clinical trial for the treatment of MPS VI subtype disease. In addition, it has a pipeline of earlier stage programs in oncology and other diseases. The company has strategic collaboration with AbbVie for the treatment of autoimmune diseases; and Boehringer Ingelheim International GmbH for developing new treatments for idiopathic pulmonary fibrosis. Inventiva S.A. was founded in 2011 and is based in Daix, France.
How the Company Makes MoneyInventiva makes money through a combination of research and development collaborations, milestone payments, and potential future product sales. As a clinical-stage company, Inventiva does not yet have products on the market but relies on partnerships with larger pharmaceutical companies to fund its research efforts. These partnerships often involve upfront payments, as well as milestone payments tied to the achievement of specific developmental, regulatory, or commercial targets. Additionally, Inventiva may generate revenue from licensing agreements, which grant other companies the rights to develop and commercialize its drug candidates. The company's long-term revenue model anticipates income from the commercialization of successfully developed therapies, pending regulatory approval.

Inventiva Earnings Call Summary

Earnings Call Date:Mar 26, 2025
(Q4-2024)
|
% Change Since: 1.09%|
Next Earnings Date:Sep 29, 2025
Earnings Call Sentiment Positive
The earnings call presented a largely positive outlook with significant progress in clinical trials, financial performance, and strategic global partnerships. However, challenges included workforce reductions and a significant increase in net loss. The highlights of strategic advancements and robust cash position outweigh the lowlights.
Q4-2024 Updates
Positive Updates
Progress in Clinical Development of lanifibranor
Completed screening for Phase 3 NATiV3 trial with positive recommendations from data monitoring committees, indicating no modifications are necessary. The trial is on track for completion of recruitment in H1 2025 and topline results expected in H2 2026.
Positive Financial Performance
Inventiva raised $184 million in 2024 through dilutive and non-dilutive financing operations, significantly increasing cash position to €96.6 million from €36 million in 2023.
Strategic Partnerships and Global Expansion
Launched clinical development of lanifibranor in Japan with partner Hepalys and secured licensing agreements in South Korea and China, positioning lanifibranor as a leading oral drug in MASH for these regions.
Strong Governance and Leadership Team
Reinforced Board of Directors with experienced members from the biotech industry, including Andre Turenne and Mark Pruzanski, to drive commercialization and strategic growth.
Strengthened Clinical Data Set
Published positive results from LEGEND trial showing significant reduction in HBA1C and improvement in insulin sensitivity with lanifibranor, particularly when combined with empagliflozin.
Negative Updates
Workforce Reduction
Decision to focus resources on lanifibranor led to the cessation of all pre-clinical activities not related to it, resulting in a reduction of approximately 50% of the workforce.
Revenue Decline
Revenues decreased to €9.2 million in 2024 compared to €17.5 million in 2023, primarily due to lower milestone payments.
Increased Net Loss
Net loss for 2024 increased to €184.2 million from €110.4 million in 2023, due to various factors including non-cash financial adjustments.
Company Guidance
During the conference call, Inventiva provided guidance on several key metrics and strategic initiatives for the fiscal year 2024. The company reported a cash position of €96.6 million at the end of 2024, compared to €36 million at the end of 2023, primarily due to successful financing operations totaling approximately $184 million. Inventiva anticipates completing the randomization of its Phase 3 NATiV3 trial for lanifibranor by the first half of 2025, with topline results expected in the second half of 2026. The company aims to utilize its strengthened financial position to prepare for regulatory filings and potential commercialization, having already reinforced its board and development team. Despite a net loss of €184.2 million in 2024, Inventiva remains focused on advancing lanifibranor, benefiting from positive trial data and strategic partnerships in Asia, with a cash runway extending to September 2025, or potentially to September 2026 with additional financing.

Inventiva Financial Statement Overview

Summary
Inventiva faces considerable financial challenges, with declining revenues, persistent losses, and high leverage. The balance sheet shows negative equity, raising concerns about long-term sustainability. While the company has managed to secure financing, the reliance on external capital and negative cash flows highlight the need for strategic improvements to stabilize and grow the business.
Income Statement
40
Negative
Inventiva's income statement shows a concerning trajectory with declining revenues from 2023 to 2024 and persistent negative net income, indicating operational challenges. The gross profit margin is consistently high, as expected for the industry, but the negative net profit margin and EBIT margin highlight significant profitability issues. The company's revenue growth has turned negative, suggesting difficulties in sustaining sales momentum.
Balance Sheet
30
Negative
The balance sheet reflects financial instability with negative stockholders' equity, indicating that liabilities exceed assets. The increasing debt-to-equity ratio is a major concern, suggesting high financial leverage and potential solvency risks. Despite these challenges, the company has maintained a consistent level of cash and short-term investments, which could provide some liquidity buffer.
Cash Flow
45
Neutral
Cash flow analysis reveals significant negative operating cash flow, indicating that the company is not generating sufficient cash from its core operations. The free cash flow is also negative, which could impact future investments and growth. However, the high financing cash flow in recent years suggests reliance on external funding to sustain operations.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue14.72M17.48M12.18M4.19M372.00K
Gross Profit9.20M17.50M11.18M3.18M-474.00K
EBITDA-96.69M-102.04M-57.11M-52.27M-31.77M
Net Income-184.21M-110.43M-54.27M-49.64M-31.62M
Balance Sheet
Total Assets118.97M69.56M116.00M121.98M138.92M
Cash, Cash Equivalents and Short-Term Investments96.56M26.99M87.78M95.38M113.02M
Total Debt54.33M37.49M34.51M10.12M13.25M
Total Liabilities225.61M101.59M70.53M33.12M27.71M
Stockholders Equity-106.65M-32.03M45.48M88.87M111.21M
Cash Flow
Free Cash Flow-86.26M-82.15M-45.49M-48.16M-30.88M
Operating Cash Flow-85.93M-81.61M-44.93M-47.63M-30.59M
Investing Cash Flow8.74M-7.73M8.87M-1.79M-8.56M
Financing Cash Flow145.59M29.08M37.27M25.45M111.67M

Inventiva Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.78
Price Trends
50DMA
2.79
Positive
100DMA
2.85
Positive
200DMA
2.63
Positive
Market Momentum
MACD
0.02
Negative
RSI
58.61
Neutral
STOCH
49.20
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For FR:IVA, the sentiment is Positive. The current price of 2.78 is below the 20-day moving average (MA) of 2.79, below the 50-day MA of 2.79, and above the 200-day MA of 2.63, indicating a bullish trend. The MACD of 0.02 indicates Negative momentum. The RSI at 58.61 is Neutral, neither overbought nor oversold. The STOCH value of 49.20 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for FR:IVA.

Inventiva Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
€590.12M-44.11%21.64%-196.47%
58
Neutral
€4.53B-148.98%18.52%
55
Neutral
€165.16M105.972.17%134.56%
51
Neutral
$7.39B0.36-62.86%2.37%15.48%-2.68%
50
Neutral
€232.38M-152.03%-40.10%
46
Neutral
€397.47M
-47.37%-26.56%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
FR:IVA
Inventiva
2.87
0.71
32.87%
FR:ABVX
Abivax SA
60.60
50.10
477.14%
FR:GNFT
Genfit
3.34
-0.44
-11.58%
FR:VLA
Valneva
3.59
0.50
16.20%
FR:DBV
DBV Technologies
1.73
0.89
105.48%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 26, 2025